Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: OPRK1 (opioid receptor kappa 1) Homo sapiens
Symbol: OPRK1
Name: opioid receptor kappa 1
Description: Exhibits dynorphin receptor activity. Involved in adenylate cyclase-inhibiting opioid receptor signaling pathway; defense response to virus; and immune response. Localizes to cytosol; integral component of plasma membrane; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: K-OR-1; kappa opioid receptor; kappa-type opioid receptor; KOP; KOR; KOR-1; KOR1; Opiate receptor, kappa-1; opioid receptor, kappa 1; OPRK
Mus musculus (house mouse) : Oprk1 (opioid receptor, kappa 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Oprk1 (opioid receptor, kappa 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Oprk1 (opioid receptor kappa 1)
Pan paniscus (bonobo/pygmy chimpanzee) : OPRK1 (opioid receptor kappa 1)
Canis lupus familiaris (dog) : OPRK1 (opioid receptor kappa 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Oprk1 (opioid receptor kappa 1)
Sus scrofa (pig) : OPRK1 (opioid receptor kappa 1)
Chlorocebus sabaeus (African green monkey) : OPRK1 (opioid receptor kappa 1)
Heterocephalus glaber (naked mole-rat) : Oprk1 (opioid receptor kappa 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl853,225,716 - 53,251,697 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl853,225,724 - 53,251,637 (-)EnsemblGRCh38hg38GRCh38
GRCh38853,225,724 - 53,251,637 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37854,138,276 - 54,164,257 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36854,300,829 - 54,326,747 (-)NCBINCBI36hg18NCBI36
Build 34854,304,325 - 54,326,525NCBI
Celera850,129,111 - 50,155,030 (-)NCBI
Cytogenetic Map8q11.23NCBI
HuRef849,605,704 - 49,631,623 (-)NCBIHuRef
CHM1_1854,189,898 - 54,215,870 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on OPRK1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69478
Created: 2001-11-27
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.