GLRX3 (glutaredoxin 3) - Rat Genome Database

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Gene: GLRX3 (glutaredoxin 3) Homo sapiens
Analyze
Symbol: GLRX3
Name: glutaredoxin 3
RGD ID: 69462
HGNC Page HGNC:15987
Description: Enables identical protein binding activity. Involved in several processes, including [2Fe-2S] cluster assembly; cell redox homeostasis; and protein maturation by iron-sulfur cluster transfer. Located in iron-sulfur cluster assembly complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: bA500G10.4; FLJ11864; GLRX4; glutaredoxin 4; glutaredoxin-3; GRX3; GRX4; PICOT; PKC-interacting cousin of thioredoxin; PKC-theta-interacting protein; PKCq-interacting protein; testicular tissue protein Li 75; thioredoxin-like 2; thioredoxin-like 3; thioredoxin-like protein 2; TXNL2; TXNL3
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: GLRX3P1   GLRX3P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810130,136,391 - 130,180,377 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl10130,136,391 - 130,184,521 (+)EnsemblGRCh38hg38GRCh38
GRCh3710131,934,655 - 131,978,641 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610131,824,653 - 131,867,860 (+)NCBINCBI36Build 36hg18NCBI36
Build 3410131,824,671 - 131,872,774NCBI
Celera10125,607,908 - 125,651,111 (+)NCBICelera
Cytogenetic Map10q26.3NCBI
HuRef10125,514,535 - 125,558,544 (+)NCBIHuRef
CHM1_110132,217,042 - 132,261,052 (+)NCBICHM1_1
T2T-CHM13v2.010131,065,390 - 131,109,374 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17alpha-ethynylestradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-tribromophenol  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-acetamidofluorene  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3-chloropropane-1,2-diol  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (ISO)
arsenite(3-)  (EXP)
arsenous acid  (EXP)
benzatropine  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Brodifacoum  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP)
calcium atom  (ISO)
calcium(0)  (ISO)
carbon nanotube  (ISO)
CGP 52608  (EXP)
chloropicrin  (EXP)
chromium(6+)  (ISO)
clobetasol  (ISO)
clofibric acid  (ISO)
clozapine  (EXP)
cocaine  (ISO)
copper(II) sulfate  (EXP)
cyclosporin A  (EXP)
decabromodiphenyl ether  (EXP)
diarsenic trioxide  (EXP)
diazinon  (EXP)
ethanol  (ISO)
finasteride  (ISO)
flavonoids  (ISO)
flutamide  (ISO)
frenolicin B  (EXP)
gentamycin  (ISO)
glutathione  (EXP)
hyaluronic acid  (ISO)
hydrogen peroxide  (EXP,ISO)
irinotecan  (EXP)
ivermectin  (EXP)
lead(0)  (EXP)
lead(2+)  (EXP)
microcystin-LR  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (ISO)
nickel atom  (EXP)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
phenylephrine  (ISO)
quartz  (EXP)
reactive oxygen species  (EXP)
silicon dioxide  (EXP)
sodium dichromate  (ISO)
tamoxifen  (ISO)
temozolomide  (EXP)
tert-butyl hydroperoxide  (EXP)
thapsigargin  (ISO)
theophylline  (EXP)
thioacetamide  (ISO)
triptonide  (ISO)
trovafloxacin  (ISO)
tunicamycin  (ISO)
valproic acid  (EXP)
vorinostat  (EXP)
zoledronic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell cortex  (IEA)
cytoplasm  (IEA,NAS)
cytosol  (IBA,IEA)
dendrite  (IEA,ISO)
iron-sulfur cluster assembly complex  (IPI)
nucleus  (IBA,IEA,ISO,NAS)
Z disc  (IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Inhibition of the c-Jun N-terminal kinase/AP-1 and NF-kappaB pathways by PICOT, a novel protein kinase C-interacting protein with a thioredoxin homology domain. Witte S, etal., J Biol Chem 2000 Jan 21;275(3):1902-9.
Additional References at PubMed
PMID:8125298   PMID:11124703   PMID:11774602   PMID:12477932   PMID:14702039   PMID:15231748   PMID:15342556   PMID:15489334   PMID:15846844   PMID:16169070   PMID:16189514   PMID:16385451  
PMID:17353931   PMID:18258855   PMID:18528843   PMID:19738201   PMID:19797004   PMID:20170406   PMID:20226171   PMID:20498481   PMID:20800603   PMID:21123948   PMID:21160409   PMID:21516116  
PMID:21575136   PMID:21873635   PMID:21900206   PMID:22309771   PMID:22623428   PMID:22658674   PMID:22678362   PMID:22863883   PMID:23376485   PMID:23415866   PMID:23615448   PMID:23891004  
PMID:24999758   PMID:25416956   PMID:25910212   PMID:25921289   PMID:25975981   PMID:26186194   PMID:26296460   PMID:26302480   PMID:26344197   PMID:26613676   PMID:26871637   PMID:26972000  
PMID:27107012   PMID:27107014   PMID:27173435   PMID:27203742   PMID:27432908   PMID:27519415   PMID:28514442   PMID:28515276   PMID:29117863   PMID:29229926   PMID:29317492   PMID:29397791  
PMID:29791485   PMID:29892012   PMID:30097533   PMID:30110629   PMID:30575818   PMID:30595380   PMID:30833792   PMID:31091453   PMID:31176019   PMID:31515488   PMID:31527584   PMID:31540324  
PMID:31868085   PMID:31980649   PMID:32296183   PMID:32414791   PMID:32416067   PMID:32429669   PMID:32910989   PMID:33961781   PMID:34079125   PMID:34709727   PMID:34794402   PMID:35032548  
PMID:35256949   PMID:35271311   PMID:35446349   PMID:35530310   PMID:35562734   PMID:35831314   PMID:35987950  


Genomics

Comparative Map Data
GLRX3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810130,136,391 - 130,180,377 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl10130,136,391 - 130,184,521 (+)EnsemblGRCh38hg38GRCh38
GRCh3710131,934,655 - 131,978,641 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610131,824,653 - 131,867,860 (+)NCBINCBI36Build 36hg18NCBI36
Build 3410131,824,671 - 131,872,774NCBI
Celera10125,607,908 - 125,651,111 (+)NCBICelera
Cytogenetic Map10q26.3NCBI
HuRef10125,514,535 - 125,558,544 (+)NCBIHuRef
CHM1_110132,217,042 - 132,261,052 (+)NCBICHM1_1
T2T-CHM13v2.010131,065,390 - 131,109,374 (+)NCBIT2T-CHM13v2.0
Glrx3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397137,039,302 - 137,071,360 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7137,039,343 - 137,070,323 (+)EnsemblGRCm39 Ensembl
GRCm387137,437,573 - 137,469,631 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7137,437,614 - 137,468,594 (+)EnsemblGRCm38mm10GRCm38
MGSCv377144,629,331 - 144,660,277 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367137,275,991 - 137,306,937 (+)NCBIMGSCv36mm8
Celera7137,253,536 - 137,284,736 (+)NCBICelera
Cytogenetic Map7F4NCBI
Glrx3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21192,241,707 - 192,272,012 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1192,241,701 - 192,272,010 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1200,608,856 - 200,638,933 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01207,760,578 - 207,790,565 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01200,434,029 - 200,464,012 (+)NCBIRnor_WKY
Rnor_6.01209,768,696 - 209,799,912 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1209,768,696 - 209,799,903 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01216,692,884 - 216,724,100 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41197,176,020 - 197,206,249 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11197,326,013 - 197,356,245 (+)NCBI
Celera1189,946,939 - 189,976,456 (+)NCBICelera
Cytogenetic Map1q41NCBI
Glrx3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554777,715,257 - 7,752,818 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554777,715,257 - 7,748,913 (+)NCBIChiLan1.0ChiLan1.0
GLRX3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.110130,973,022 - 131,019,741 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10130,973,022 - 131,019,742 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v010126,730,314 - 126,775,918 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
GLRX3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12838,724,895 - 38,755,323 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2838,724,941 - 38,755,316 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2838,781,705 - 38,812,290 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02839,360,801 - 39,391,612 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2839,360,806 - 39,391,610 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12838,847,851 - 38,878,212 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02838,836,160 - 38,866,776 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02839,090,506 - 39,121,238 (+)NCBIUU_Cfam_GSD_1.0
Glrx3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244072138,328,180 - 8,354,031 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648617,207,309 - 17,233,171 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493648617,201,838 - 17,233,171 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GLRX3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14139,072,575 - 139,111,249 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114139,072,554 - 139,108,063 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214151,189,259 - 151,224,776 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GLRX3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19122,737,101 - 122,780,001 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9122,737,379 - 122,781,391 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604884,120,319 - 84,163,350 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Glrx3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473716,905,964 - 16,938,048 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473716,906,135 - 16,938,089 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GLRX3
3 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1114
Count of miRNA genes:685
Interacting mature miRNAs:754
Transcripts:ENST00000331244, ENST00000368644, ENST00000481034, ENST00000486974, ENST00000496195
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH91792  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710131,977,702 - 131,977,849UniSTSGRCh37
GRCh3763,979,379 - 3,979,525UniSTSGRCh37
Build 3663,924,378 - 3,924,524RGDNCBI36
Celera10125,650,943 - 125,651,090UniSTS
Celera65,208,333 - 5,208,479RGD
Cytogenetic Map10q26UniSTS
Cytogenetic Map6p25.2UniSTS
HuRef10125,557,599 - 125,557,746UniSTS
HuRef63,856,230 - 3,856,376UniSTS
SHGC-86234  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710131,962,642 - 131,962,834UniSTSGRCh37
Build 3610131,852,632 - 131,852,824RGDNCBI36
Celera10125,635,883 - 125,636,075RGD
Cytogenetic Map10q26UniSTS
HuRef10125,542,535 - 125,542,727UniSTS
TNG Radiation Hybrid Map1036919.0UniSTS
STS-H99205  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710131,982,497 - 131,982,618UniSTSGRCh37
Build 3610131,872,487 - 131,872,608RGDNCBI36
Celera10125,655,739 - 125,655,860RGD
Cytogenetic Map10q26UniSTS
HuRef10125,562,395 - 125,562,516UniSTS
GeneMap99-GB4 RH Map10557.0UniSTS
NCBI RH Map101382.8UniSTS
25499  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710131,964,857 - 131,965,240UniSTSGRCh37
GRCh3763,978,890 - 3,979,034UniSTSGRCh37
Build 3663,923,889 - 3,924,033RGDNCBI36
Celera65,207,844 - 5,207,988RGD
Celera10125,638,098 - 125,638,481UniSTS
Cytogenetic Map6p25.2UniSTS
Cytogenetic Map10q26UniSTS
HuRef63,855,741 - 3,855,885UniSTS
HuRef10125,544,750 - 125,545,133UniSTS
TNG Radiation Hybrid Map62229.0UniSTS
Stanford-G3 RH Map681.0UniSTS
NCBI RH Map633.9UniSTS
GeneMap99-G3 RH Map681.0UniSTS
DBEST25498  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3763,978,403 - 3,978,682UniSTSGRCh37
Build 3663,923,402 - 3,923,681RGDNCBI36
Celera65,207,357 - 5,207,636RGD
Cytogenetic Map10q26UniSTS
Cytogenetic Map6p25.2UniSTS
HuRef63,855,254 - 3,855,533UniSTS
Stanford-G3 RH Map674.0UniSTS
NCBI RH Map631.9UniSTS
GeneMap99-G3 RH Map674.0UniSTS
D11S2921  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map1p36.1UniSTS
Cytogenetic Map3p24.2UniSTS
Cytogenetic Map1q23.3UniSTS
Cytogenetic Map9q34.3UniSTS
Cytogenetic Map1p36.31UniSTS
Cytogenetic Map3p25.3UniSTS
Cytogenetic Map11p15.4UniSTS
Cytogenetic Map7p14.1UniSTS
Cytogenetic Map2q22.3UniSTS
Cytogenetic Map9q22.33UniSTS
Cytogenetic Map15q13.2UniSTS
Cytogenetic Map16q24.3UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map19q13.11UniSTS
Cytogenetic Map17p11.2UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map14q13.2UniSTS
Cytogenetic Map2p25.1UniSTS
Cytogenetic Map10q24.33UniSTS
Cytogenetic Map5q23.3-q31.1UniSTS
Cytogenetic Map8p21.3UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map1p32.3UniSTS
Cytogenetic Map17q11UniSTS
Cytogenetic Map1q24UniSTS
Cytogenetic Map11q14UniSTS
Cytogenetic Map17q25UniSTS
Cytogenetic MapXq13.1UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map9p13.3UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map2q32.3UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map4q32.1UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map13q12UniSTS
Cytogenetic Map12p13.31UniSTS
Cytogenetic Map3p21.1UniSTS
Cytogenetic Map3q12.3UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic Map6q22UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map20q11UniSTS
Cytogenetic Map8q22.1UniSTS
Cytogenetic Map5q23.3UniSTS
Cytogenetic Map20q11.22UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map17q21UniSTS
Cytogenetic Map11q25UniSTS
Cytogenetic Map3p21.3UniSTS
Cytogenetic Map1q32.3UniSTS
Cytogenetic Map2q37.3UniSTS
Cytogenetic Map12q21.33UniSTS
Cytogenetic Map7p22.3UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map1p35.1UniSTS
Cytogenetic MapXp11.4-p11.3UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map1q24.1UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map11q24.2UniSTS
Cytogenetic Map10p15.1UniSTS
Cytogenetic Map18p11.31UniSTS
Cytogenetic Map12p13.32UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map11q13.5UniSTS
Cytogenetic Map1p22UniSTS
Cytogenetic Map2q14UniSTS
Cytogenetic Map16q24UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map7p22UniSTS
Cytogenetic Map14q32.33UniSTS
Cytogenetic Map8p11.21UniSTS
Cytogenetic Map8q24.11UniSTS
Cytogenetic Map4q12UniSTS
Cytogenetic Map9q22.31UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic Map11p15.5UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map5q31.1UniSTS
Cytogenetic Map2q33-q34UniSTS
Cytogenetic Map17q22.2UniSTS
Cytogenetic Map8q24.13UniSTS
Cytogenetic Map22q11.2UniSTS
Cytogenetic Map6p22.1UniSTS
Cytogenetic MapYp11.2UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map18p11.21UniSTS
Cytogenetic Map10q22UniSTS
Cytogenetic Map5q35.3UniSTS
Cytogenetic Map10q23.1UniSTS
Cytogenetic Map2q37UniSTS
Cytogenetic Map18pter-p11.3UniSTS
Cytogenetic Map8q22.3UniSTS
Cytogenetic Map6p21.33UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map2q21.3UniSTS
Cytogenetic Map2q21.1UniSTS
Cytogenetic Map8p21.2UniSTS
Cytogenetic MapXq22.1UniSTS
Cytogenetic Map10q22.2UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map19q13.41UniSTS
Cytogenetic Map14q32.12UniSTS
Cytogenetic Map3q21.3UniSTS
Cytogenetic Map4q34.1UniSTS
Cytogenetic Map10p13UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map3q13.31UniSTS
Cytogenetic Map7q21.12UniSTS
Cytogenetic Map15q22.2UniSTS
Cytogenetic Map8p23.1UniSTS
Cytogenetic Map5q32UniSTS
Cytogenetic Map20q13.12UniSTS
Cytogenetic Map12q23.2UniSTS
Cytogenetic Map6p22UniSTS
Cytogenetic Map11q12.3UniSTS
Cytogenetic Map11p13UniSTS
Cytogenetic Map1q21.3UniSTS
Cytogenetic Map16p13.13UniSTS
Cytogenetic Map1p34UniSTS
Cytogenetic Map1p36.21UniSTS
Cytogenetic Map12q13UniSTS
Cytogenetic Map19q13.31UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map4p14UniSTS
Cytogenetic Map1q44UniSTS
Cytogenetic Map19p13.1-p12UniSTS
Cytogenetic Map7q22UniSTS
Cytogenetic Map8q24UniSTS
Cytogenetic Map18p11.31-p11.21UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map7p21.2UniSTS
Cytogenetic Map12q23-q24.1UniSTS
Cytogenetic Map15q15.1UniSTS
Cytogenetic Map10q11.23UniSTS
Cytogenetic Map5q14.1UniSTS
Cytogenetic Map5p15.33UniSTS
Cytogenetic Map1q21UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map1q42.1UniSTS
Cytogenetic Map12p13UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map2q12.3UniSTS
Cytogenetic Map19q13.3-q13.4UniSTS
Cytogenetic Map15q11.2UniSTS
Cytogenetic Map5q35UniSTS
Cytogenetic Map8p23-p22UniSTS
Cytogenetic Map12p11UniSTS
Cytogenetic Map17q21-q22UniSTS
Cytogenetic Map12q13.12UniSTS
Cytogenetic Map2q36.1UniSTS
Cytogenetic Map11p13-p12UniSTS
Cytogenetic MapXp22.33UniSTS
Cytogenetic MapYp11.3UniSTS
Cytogenetic Map2q12.1UniSTS
Cytogenetic Map3p21.31UniSTS
Cytogenetic Map3q26.32UniSTS
Cytogenetic Map7q11.21UniSTS
Cytogenetic Map10q11.22UniSTS
Cytogenetic Map17p12UniSTS
Cytogenetic Map3p25.1UniSTS
Cytogenetic Map14q32UniSTS
Cytogenetic Map5q12-q13UniSTS
Cytogenetic Map6p23UniSTS
Cytogenetic Map20p12.3-p11.21UniSTS
Cytogenetic Map17q11.2-q12UniSTS
Cytogenetic Map11q23.3UniSTS
Cytogenetic Map12q13.3UniSTS
Cytogenetic Map10q23-q24UniSTS
Cytogenetic Map14q21.3UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map12q13-q14UniSTS
Cytogenetic Map6q14.1UniSTS
Cytogenetic Map3q26.33UniSTS
Cytogenetic MapXp22.2UniSTS
Cytogenetic Map1p31UniSTS
Cytogenetic Map15q15-q21.1UniSTS
Cytogenetic Map9q32UniSTS
Cytogenetic Map17p13UniSTS
Cytogenetic Map7q21-q22UniSTS
Cytogenetic Map16q24.1UniSTS
Cytogenetic Map2q33.3UniSTS
Cytogenetic Map11q22.1UniSTS
Cytogenetic Map1p13.3UniSTS
Cytogenetic Map20p13UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic Map7q36.3UniSTS
Cytogenetic Map5q12.3UniSTS
Cytogenetic Map2q33.2UniSTS
Cytogenetic Map12q22UniSTS
Cytogenetic Map21p11.1UniSTS
Cytogenetic Map14q23.2UniSTS
Cytogenetic Map6p22.3-p22.1UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map6q15UniSTS
Cytogenetic MapXq25-q26.3UniSTS
Cytogenetic Map10q22.3UniSTS
Cytogenetic Map12q24.31-q24.32UniSTS
Cytogenetic Map16p12.3UniSTS
Cytogenetic Map9q33.2UniSTS
Cytogenetic Map15q23UniSTS
Cytogenetic Map12p12.2-p11.2UniSTS
Cytogenetic Map2q14.3UniSTS
Cytogenetic MapXp11UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map17q22UniSTS
Cytogenetic Map3q21UniSTS
Cytogenetic Map20q13.2UniSTS
Cytogenetic Map10q26UniSTS
Cytogenetic Map6q22.31UniSTS
Cytogenetic Map3q27.1UniSTS
Cytogenetic Map7p13UniSTS
Cytogenetic Map22q13UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map18p11.32UniSTS
Cytogenetic Map12q15UniSTS
Cytogenetic MapXq22.3UniSTS
Cytogenetic Map2p25.3UniSTS
Cytogenetic Map16q21UniSTS
Cytogenetic Map11q23.1UniSTS
Cytogenetic Map3q13.13UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map3q27.3UniSTS
Cytogenetic Map4p13UniSTS
Cytogenetic Map16p12.1UniSTS
Cytogenetic Map14q32.11UniSTS
Cytogenetic Map7p14.3UniSTS
Cytogenetic Map16q12.1UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map9q21.13UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map3q29UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic Map16q22.2UniSTS
Cytogenetic Map19p13.12UniSTS
Cytogenetic Map20q13.1UniSTS
Cytogenetic Map3p14.3UniSTS
Cytogenetic Map10q23.33UniSTS
Cytogenetic Map12p12UniSTS
Cytogenetic Map9p24.1-p23UniSTS
Cytogenetic Map15q22UniSTS
Cytogenetic Map6p25UniSTS
Cytogenetic MapXq12-q13UniSTS
Cytogenetic Map2p16.1UniSTS
Cytogenetic Map14q23UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map17q23.3UniSTS
Cytogenetic Map1q42.1-q43UniSTS
Cytogenetic Map7q31.1-q31.3UniSTS
Cytogenetic Map20q11.21UniSTS
Cytogenetic Map20q12-q13.12UniSTS
Cytogenetic Map1q24-q25.3UniSTS
Cytogenetic Map20p12.1UniSTS
Cytogenetic Map14q32.31UniSTS
Cytogenetic Map1p13.2UniSTS
Cytogenetic Map2p13.3UniSTS
Cytogenetic Map6q25.1-q26UniSTS
Cytogenetic Map12q13.11-q14.3UniSTS
Cytogenetic Map7p11UniSTS
Cytogenetic Map12p11.22UniSTS
Cytogenetic Map17q23.1UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map9q34.11UniSTS
Cytogenetic Map2p15UniSTS
Cytogenetic Map9p11UniSTS
Cytogenetic Map6p24.3UniSTS
Cytogenetic Map9p24.1UniSTS
Cytogenetic Map12p13.2UniSTS
Cytogenetic Map6p22.2UniSTS
Cytogenetic Map12q24.2-q24.31UniSTS
Cytogenetic Map22q12.2UniSTS
Cytogenetic Map11p11.11UniSTS
Cytogenetic Map11q22-q23UniSTS
Cytogenetic Map11q14.1UniSTS
Cytogenetic Map1q32.1UniSTS
Cytogenetic Map15q22-q23UniSTS
Cytogenetic Map9p21UniSTS
Cytogenetic Map15q13.1UniSTS
Cytogenetic Map15q22-qterUniSTS
Cytogenetic Map10q25UniSTS
Cytogenetic Map6p22.3UniSTS
Cytogenetic Map6p25.2UniSTS
Cytogenetic Map5p15.1UniSTS
Cytogenetic Map2p21UniSTS
Cytogenetic Map22q13.31UniSTS
Cytogenetic Map21q22.2UniSTS
Cytogenetic Map19q13.33UniSTS
Cytogenetic Map14q24.1UniSTS
Cytogenetic Map13q34UniSTS
Cytogenetic Map18q11.2UniSTS
Cytogenetic Map6q25.1UniSTS
Cytogenetic Map20q11.23UniSTS
Cytogenetic Map1q21.1UniSTS
Cytogenetic Map17q24.3UniSTS
Cytogenetic Map16q11.2UniSTS
Cytogenetic Map16p12.2UniSTS
Cytogenetic Map11q24UniSTS
Cytogenetic Map2q23.3UniSTS
Cytogenetic Map1p31.1UniSTS
Cytogenetic Map18q23UniSTS
Cytogenetic Map11q13.4UniSTS
Cytogenetic Map7p21.1UniSTS
Cytogenetic Map2q37.1UniSTS
Cytogenetic Map8p11.2UniSTS
Cytogenetic Map9q33.3UniSTS
Cytogenetic Map4q22.1UniSTS
Cytogenetic Map2q21.2UniSTS
Cytogenetic Map15q13.3UniSTS
Cytogenetic Map7p15.3UniSTS
Cytogenetic Map3p22.2UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map19p13.2-cenUniSTS
Cytogenetic Map19p13.3-p13.2UniSTS
Cytogenetic Map13q32.3UniSTS
Cytogenetic Map9q33UniSTS
Cytogenetic Map1p36-p35UniSTS
Cytogenetic Map19q13.1UniSTS
Cytogenetic MapXq25UniSTS
Cytogenetic Map12q23UniSTS
Cytogenetic Map21q22.13UniSTS
Cytogenetic Map2q24.2UniSTS
Cytogenetic Map7q31.1-q31.2UniSTS
Cytogenetic Map22q11.23UniSTS
Cytogenetic MapXq24UniSTS
Cytogenetic Map4q25-q27UniSTS
Cytogenetic Map3q25.33UniSTS
Cytogenetic MapXq26.2UniSTS
Cytogenetic Map8q13.2UniSTS
Cytogenetic Map8q13.1UniSTS
Cytogenetic Map8q22.2UniSTS
Cytogenetic Map6q21UniSTS
Cytogenetic Map5q23.1UniSTS
Cytogenetic Map4q13.3UniSTS
Cytogenetic Map3p26.1UniSTS
Cytogenetic Map1q21.2UniSTS
Cytogenetic Map17p13.1UniSTS
Cytogenetic Map3p22-p21.3UniSTS
Cytogenetic Map12qUniSTS
Cytogenetic MapXq21.3UniSTS
Cytogenetic Map12q12UniSTS
Cytogenetic Map20p11UniSTS
Cytogenetic Map6p12.3UniSTS
Cytogenetic Map5p13.1-p12UniSTS
Cytogenetic Map1p36.22UniSTS
Cytogenetic Map9q34UniSTS
Cytogenetic Map7q21.13UniSTS
Cytogenetic Map20q13.33UniSTS
Cytogenetic Map3p21.1-p14.3UniSTS
Cytogenetic Map2q33.1UniSTS
Cytogenetic Map7q36.1UniSTS
Cytogenetic Map10q24.31UniSTS
Cytogenetic Map2p25.1-p24.1UniSTS
Cytogenetic Map3q23UniSTS
Cytogenetic Map13q12.11UniSTS
Cytogenetic Map12q14.3UniSTS
Cytogenetic Map13q14.13UniSTS
Cytogenetic Map11p15UniSTS
Cytogenetic Map6q14.3-q16.1UniSTS
Cytogenetic Map16p13.2UniSTS
Cytogenetic Map16q22.3UniSTS
Cytogenetic Map1p32-p31UniSTS
Cytogenetic Map12q13.13UniSTS
Cytogenetic Map8p11UniSTS
Cytogenetic Map6q25UniSTS
Cytogenetic Map8p11.23UniSTS
Cytogenetic Map9p24.3UniSTS
Cytogenetic Map7q35UniSTS
Cytogenetic Map11q22.3UniSTS
Cytogenetic Map16p12UniSTS
Cytogenetic Map6q14.3UniSTS
Cytogenetic Map7q36UniSTS
Cytogenetic Map1q22UniSTS
Cytogenetic Map10p15.3UniSTS
Cytogenetic Map8p12UniSTS
Cytogenetic Map13q12.2UniSTS
Cytogenetic Map7p22.1UniSTS
Cytogenetic Map6p21.2UniSTS
Cytogenetic Map18q21.1UniSTS
Cytogenetic Map10p11.21UniSTS
Cytogenetic Map10p14UniSTS
Cytogenetic Map3p26UniSTS
Cytogenetic Map9q22.3UniSTS
Cytogenetic Map17q21.1-q21.3UniSTS
Cytogenetic Map6q11.1UniSTS
Cytogenetic Map5q13.2UniSTS
Cytogenetic Map3q21.1UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map22q13.1-q13.2UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map9q32-q33.3UniSTS
Cytogenetic Map8q21.2UniSTS
Cytogenetic Map18q12.1UniSTS
Cytogenetic Map12p13.2-p12.3UniSTS
Cytogenetic Map1p36.3-p36.2UniSTS
Cytogenetic Map5q11.2UniSTS
Cytogenetic Map1q25.2UniSTS
Cytogenetic Map3q13.2UniSTS
Cytogenetic Map8p22UniSTS
Cytogenetic Map1q25.1UniSTS
Cytogenetic Map18q21.32UniSTS
Cytogenetic Map17q21.2UniSTS
Cytogenetic Map15q26.2UniSTS
Cytogenetic Map14q22.1UniSTS
Cytogenetic Map5p15.2UniSTS
Cytogenetic Map12q23.1UniSTS
Cytogenetic Map10q24.2UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic Map1p22.2UniSTS
Cytogenetic Map7q32UniSTS
Cytogenetic Map5p13UniSTS
Cytogenetic Map16q23.2UniSTS
Cytogenetic Map10q24-q25UniSTS
Cytogenetic Map7p11.1UniSTS
Cytogenetic Map14q11.2-q21UniSTS
Cytogenetic Map14q12UniSTS
Cytogenetic Map12q24.13UniSTS
Cytogenetic Map10q21-q22UniSTS
Cytogenetic Map4q22UniSTS
Cytogenetic Map9q22.2UniSTS
Cytogenetic Map10q23.31UniSTS
Cytogenetic Map2p13.1UniSTS
Cytogenetic Map2p24.1UniSTS
Cytogenetic Map19p13UniSTS
Cytogenetic Map7p13-p11.1UniSTS
Cytogenetic Map7q21.1-q22UniSTS
Cytogenetic Map1p36.3UniSTS
Cytogenetic Map15q26.1UniSTS
Cytogenetic Map2q32.1UniSTS
Cytogenetic Map5p14.3UniSTS
Cytogenetic MapXp22.13UniSTS
Cytogenetic Map13q14.2UniSTS
Cytogenetic Map15qUniSTS
Cytogenetic Map7qUniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map10q23UniSTS
Cytogenetic Map5p12UniSTS
Cytogenetic Map11p11.2UniSTS
Cytogenetic Map10q11.21UniSTS
Cytogenetic Map20q13.13UniSTS
Cytogenetic Map13q22.1UniSTS
Cytogenetic Map15q21.2UniSTS
Cytogenetic MapXq28UniSTS
Cytogenetic Map9p13.1UniSTS
Cytogenetic Map9q34.13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2170 1751 1503 404 1137 271 3963 1505 2252 363 1436 1605 149 1 1176 2404 6 2
Low 269 1239 223 220 813 194 394 692 1482 56 24 8 26 28 384
Below cutoff 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_029886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001199868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001321980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_006541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017015474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA995117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF118649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF118652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ010841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK022131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK225609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL139123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC014372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI256922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP347054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM005388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000331244   ⟹   ENSP00000330836
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl10130,136,391 - 130,179,672 (+)Ensembl
RefSeq Acc Id: ENST00000368644   ⟹   ENSP00000357633
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl10130,136,399 - 130,182,881 (+)Ensembl
RefSeq Acc Id: ENST00000481034   ⟹   ENSP00000435445
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl10130,136,399 - 130,184,521 (+)Ensembl
RefSeq Acc Id: ENST00000486974
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl10130,159,746 - 130,160,873 (+)Ensembl
RefSeq Acc Id: ENST00000496195
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl10130,179,374 - 130,180,382 (+)Ensembl
RefSeq Acc Id: ENST00000619341
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl10130,180,185 - 130,183,643 (+)Ensembl
RefSeq Acc Id: NM_001199868   ⟹   NP_001186797
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810130,136,391 - 130,180,377 (+)NCBI
GRCh3710131,934,639 - 131,978,646 (+)ENTREZGENE
HuRef10125,514,535 - 125,558,544 (+)ENTREZGENE
CHM1_110132,217,042 - 132,261,052 (+)NCBI
T2T-CHM13v2.010131,065,390 - 131,109,374 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001321980   ⟹   NP_001308909
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810130,136,391 - 130,179,672 (+)NCBI
CHM1_110132,217,076 - 132,260,338 (+)NCBI
T2T-CHM13v2.010131,065,390 - 131,108,669 (+)NCBI
Sequence:
RefSeq Acc Id: NM_006541   ⟹   NP_006532
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810130,136,391 - 130,179,672 (+)NCBI
GRCh3710131,934,639 - 131,978,646 (+)ENTREZGENE
Build 3610131,824,653 - 131,867,860 (+)NCBI Archive
HuRef10125,514,535 - 125,558,544 (+)ENTREZGENE
CHM1_110132,217,042 - 132,260,338 (+)NCBI
T2T-CHM13v2.010131,065,390 - 131,108,669 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001186797   ⟸   NM_001199868
- Peptide Label: isoform 1
- UniProtKB: Q9P1B1 (UniProtKB/Swiss-Prot),   O76003 (UniProtKB/Swiss-Prot),   A0A140VJK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_006532   ⟸   NM_006541
- Peptide Label: isoform 1
- UniProtKB: Q9P1B1 (UniProtKB/Swiss-Prot),   O76003 (UniProtKB/Swiss-Prot),   A0A140VJK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001308909   ⟸   NM_001321980
- Peptide Label: isoform 2
- Sequence:
RefSeq Acc Id: ENSP00000330836   ⟸   ENST00000331244
RefSeq Acc Id: ENSP00000435445   ⟸   ENST00000481034
RefSeq Acc Id: ENSP00000357633   ⟸   ENST00000368644
Protein Domains
Glutaredoxin   Thioredoxin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O76003-F1-model_v2 AlphaFold O76003 1-335 view protein structure

Promoters
RGD ID:7219009
Promoter ID:EPDNEW_H15250
Type:initiation region
Name:GLRX3_1
Description:glutaredoxin 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15249  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810130,136,399 - 130,136,459EPDNEW
RGD ID:6787730
Promoter ID:HG_KWN:11669
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000368644,   OTTHUMT00000051020,   OTTHUMT00000051022
Position:
Human AssemblyChrPosition (strand)Source
Build 3610131,824,394 - 131,824,894 (+)MPROMDB
RGD ID:6851920
Promoter ID:EP73766
Type:multiple initiation site
Name:HS_TXNL2
Description:Thioredoxin-like 2.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:NEDO full length human cDNA sequencing project.; Oligo-capping
Position:
Human AssemblyChrPosition (strand)Source
Build 3610131,824,657 - 131,824,717EPD

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 10q25.2-26.3(chr10:111313099-133620674)x3 copy number gain See cases [RCV000051218] Chr10:111313099..133620674 [GRCh38]
Chr10:113072857..135434178 [GRCh37]
Chr10:113062847..135284168 [NCBI36]
Chr10:10q25.2-26.3
pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:123307835-133620674)x1 copy number loss See cases [RCV000051150] Chr10:123307835..133620674 [GRCh38]
Chr10:125067351..135434178 [GRCh37]
Chr10:125057341..135284168 [NCBI36]
Chr10:10q26.13-26.3
pathogenic
GRCh38/hg38 10q26.12-26.3(chr10:120454430-133620674)x1 copy number loss See cases [RCV000051103] Chr10:120454430..133620674 [GRCh38]
Chr10:122213942..135434178 [GRCh37]
Chr10:122203932..135284168 [NCBI36]
Chr10:10q26.12-26.3
pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:122265252-133620674)x1 copy number loss See cases [RCV000051069] Chr10:122265252..133620674 [GRCh38]
Chr10:124024767..135434178 [GRCh37]
Chr10:124014757..135284168 [NCBI36]
Chr10:10q26.13-26.3
pathogenic
GRCh38/hg38 10q26.2-26.3(chr10:126256585-133613938)x1 copy number loss See cases [RCV000052612] Chr10:126256585..133613938 [GRCh38]
Chr10:127945154..135427442 [GRCh37]
Chr10:127935144..135277432 [NCBI36]
Chr10:10q26.2-26.3
pathogenic
GRCh38/hg38 10q26.2-26.3(chr10:127500483-133620674)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052613]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052613]|See cases [RCV000052613] Chr10:127500483..133620674 [GRCh38]
Chr10:129298747..135434178 [GRCh37]
Chr10:129188737..135284168 [NCBI36]
Chr10:10q26.2-26.3
pathogenic
GRCh38/hg38 10q26.3(chr10:129673966-133613938)x1 copy number loss See cases [RCV000052614] Chr10:129673966..133613938 [GRCh38]
Chr10:131472230..135427442 [GRCh37]
Chr10:131362220..135277432 [NCBI36]
Chr10:10q26.3
pathogenic
GRCh38/hg38 10q26.3(chr10:129758596-133620674)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052615]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052615]|See cases [RCV000052615] Chr10:129758596..133620674 [GRCh38]
Chr10:131556860..135434178 [GRCh37]
Chr10:131446850..135284168 [NCBI36]
Chr10:10q26.3
pathogenic
GRCh38/hg38 10q26.3(chr10:129763050-131379342)x1 copy number loss See cases [RCV000052616] Chr10:129763050..131379342 [GRCh38]
Chr10:131561314..133177605 [GRCh37]
Chr10:131451304..133067595 [NCBI36]
Chr10:10q26.3
pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:123580320-133558988)x1 copy number loss See cases [RCV000052611] Chr10:123580320..133558988 [GRCh38]
Chr10:125339836..135372492 [GRCh37]
Chr10:125329826..135222482 [NCBI36]
Chr10:10q26.13-26.3
pathogenic
GRCh38/hg38 10q26.3(chr10:129904929-130552922)x1 copy number loss See cases [RCV000053254] Chr10:129904929..130552922 [GRCh38]
Chr10:131703193..132351186 [GRCh37]
Chr10:131593183..132241176 [NCBI36]
Chr10:10q26.3
uncertain significance
GRCh38/hg38 10q23.31-26.3(chr10:91048545-133620674)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053560]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053560]|See cases [RCV000053560] Chr10:91048545..133620674 [GRCh38]
Chr10:92808302..135434178 [GRCh37]
Chr10:92798282..135284168 [NCBI36]
Chr10:10q23.31-26.3
pathogenic
GRCh38/hg38 10q24.31-26.3(chr10:100194215-132432797)x3 copy number gain See cases [RCV000053564] Chr10:100194215..132432797 [GRCh38]
Chr10:101953972..134246301 [GRCh37]
Chr10:101943962..134096291 [NCBI36]
Chr10:10q24.31-26.3
pathogenic
GRCh38/hg38 10q25.1-26.3(chr10:106925303-133620815)x3 copy number gain See cases [RCV000053588] Chr10:106925303..133620815 [GRCh38]
Chr10:108685061..135434319 [GRCh37]
Chr10:108675051..135284309 [NCBI36]
Chr10:10q25.1-26.3
pathogenic
GRCh38/hg38 10q26.11-26.3(chr10:117866565-133554210)x3 copy number gain See cases [RCV000053589] Chr10:117866565..133554210 [GRCh38]
Chr10:119626076..135367714 [GRCh37]
Chr10:119616066..135217704 [NCBI36]
Chr10:10q26.11-26.3
pathogenic
NM_001199868.1(GLRX3):c.201+1811A>T single nucleotide variant Lung cancer [RCV000108819] Chr10:130147130 [GRCh38]
Chr10:131945394 [GRCh37]
Chr10:10q26.3
uncertain significance
GRCh38/hg38 10q25.1-26.3(chr10:108102587-133620674)x3 copy number gain See cases [RCV000133688] Chr10:108102587..133620674 [GRCh38]
Chr10:109862345..135434178 [GRCh37]
Chr10:109852335..135284168 [NCBI36]
Chr10:10q25.1-26.3
pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:125657472-133620674)x1 copy number loss See cases [RCV000133741] Chr10:125657472..133620674 [GRCh38]
Chr10:127346041..135434178 [GRCh37]
Chr10:127336031..135284168 [NCBI36]
Chr10:10q26.13-26.3
pathogenic
GRCh38/hg38 10q26.2-26.3(chr10:126730896-133620609)x1 copy number loss See cases [RCV000134040] Chr10:126730896..133620609 [GRCh38]
Chr10:128419465..135434113 [GRCh37]
Chr10:128409455..135284103 [NCBI36]
Chr10:10q26.2-26.3
pathogenic
GRCh38/hg38 10q26.2-26.3(chr10:127640489-132776585)x1 copy number loss See cases [RCV000135728] Chr10:127640489..132776585 [GRCh38]
Chr10:129438753..134590089 [GRCh37]
Chr10:129328743..134440079 [NCBI36]
Chr10:10q26.2-26.3
pathogenic
GRCh38/hg38 10q26.3(chr10:129549258-133620674)x1 copy number loss See cases [RCV000135547] Chr10:129549258..133620674 [GRCh38]
Chr10:131347522..135434178 [GRCh37]
Chr10:131237512..135284168 [NCBI36]
Chr10:10q26.3
pathogenic|likely benign
GRCh38/hg38 10q26.13-26.3(chr10:124473108-133620609)x1 copy number loss See cases [RCV000136028] Chr10:124473108..133620609 [GRCh38]
Chr10:126161677..135434113 [GRCh37]
Chr10:126151667..135284103 [NCBI36]
Chr10:10q26.13-26.3
pathogenic
GRCh38/hg38 10q26.3(chr10:128872419-133564028)x3 copy number gain See cases [RCV000136888] Chr10:128872419..133564028 [GRCh38]
Chr10:130670683..135377532 [GRCh37]
Chr10:130560673..135227522 [NCBI36]
Chr10:10q26.3
pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:124834858-133622588)x1 copy number loss See cases [RCV000137653] Chr10:124834858..133622588 [GRCh38]
Chr10:126523427..135436092 [GRCh37]
Chr10:126513417..135286082 [NCBI36]
Chr10:10q26.13-26.3
pathogenic
GRCh38/hg38 10q26.2-26.3(chr10:128549913-133622588)x1 copy number loss See cases [RCV000138159] Chr10:128549913..133622588 [GRCh38]
Chr10:130348177..135436092 [GRCh37]
Chr10:130238167..135286082 [NCBI36]
Chr10:10q26.2-26.3
pathogenic|uncertain significance
GRCh38/hg38 10q26.2-26.3(chr10:127849717-133622588)x1 copy number loss See cases [RCV000138160] Chr10:127849717..133622588 [GRCh38]
Chr10:129647981..135436092 [GRCh37]
Chr10:129537971..135286082 [NCBI36]
Chr10:10q26.2-26.3
pathogenic|likely benign
GRCh38/hg38 10q24.31-26.3(chr10:100600492-133622588)x3 copy number gain See cases [RCV000137747] Chr10:100600492..133622588 [GRCh38]
Chr10:102360249..135436092 [GRCh37]
Chr10:102350239..135286082 [NCBI36]
Chr10:10q24.31-26.3
pathogenic
GRCh38/hg38 10q26.3(chr10:129427520-133622588)x1 copy number loss See cases [RCV000137959] Chr10:129427520..133622588 [GRCh38]
Chr10:131225784..135436092 [GRCh37]
Chr10:131115774..135286082 [NCBI36]
Chr10:10q26.3
pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:122881207-133620609)x1 copy number loss See cases [RCV000138435] Chr10:122881207..133620609 [GRCh38]
Chr10:124640723..135434113 [GRCh37]
Chr10:124630713..135284103 [NCBI36]
Chr10:10q26.13-26.3
pathogenic
GRCh38/hg38 10q26.12-26.3(chr10:120970558-133622588)x1 copy number loss See cases [RCV000139344] Chr10:120970558..133622588 [GRCh38]
Chr10:122730071..135436092 [GRCh37]
Chr10:122720061..135286082 [NCBI36]
Chr10:10q26.12-26.3
pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:125316124-130269667)x1 copy number loss See cases [RCV000139127] Chr10:125316124..130269667 [GRCh38]
Chr10:127004693..132067931 [GRCh37]
Chr10:126994683..131957921 [NCBI36]
Chr10:10q26.13-26.3
likely benign
GRCh38/hg38 10q26.13-26.3(chr10:125021995-133620609)x1 copy number loss See cases [RCV000139588] Chr10:125021995..133620609 [GRCh38]
Chr10:126710564..135434113 [GRCh37]
Chr10:126700554..135284103 [NCBI36]
Chr10:10q26.13-26.3
pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:125452905-133785874)x3 copy number gain See cases [RCV000141337] Chr10:125452905..133785874 [GRCh38]
Chr10:127141474..135523199 [GRCh37]
Chr10:127131464..135373189 [NCBI36]
Chr10:10q26.13-26.3
pathogenic
GRCh38/hg38 10q26.2-26.3(chr10:127664168-133622588)x3 copy number gain See cases [RCV000140974] Chr10:127664168..133622588 [GRCh38]
Chr10:129462432..135436092 [GRCh37]
Chr10:129352422..135286082 [NCBI36]
Chr10:10q26.2-26.3
likely pathogenic
GRCh38/hg38 10q26.11-26.3(chr10:119707856-133613639)x3 copy number gain See cases [RCV000142005] Chr10:119707856..133613639 [GRCh38]
Chr10:121467368..135427143 [GRCh37]
Chr10:121457358..135277133 [NCBI36]
Chr10:10q26.11-26.3
pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:121588992-133620674)x1 copy number loss See cases [RCV000142441] Chr10:121588992..133620674 [GRCh38]
Chr10:123348506..135434178 [GRCh37]
Chr10:123338496..135284168 [NCBI36]
Chr10:10q26.13-26.3
pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:121918547-133620674)x1 copy number loss See cases [RCV000142737] Chr10:121918547..133620674 [GRCh38]
Chr10:123678062..135434178 [GRCh37]
Chr10:123668052..135284168 [NCBI36]
Chr10:10q26.13-26.3
pathogenic
GRCh38/hg38 10q26.2-26.3(chr10:127435985-133622588)x1 copy number loss See cases [RCV000143241] Chr10:127435985..133622588 [GRCh38]
Chr10:129234249..135436092 [GRCh37]
Chr10:129124239..135286082 [NCBI36]
Chr10:10q26.2-26.3
pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:123986772-133613639)x1 copy number loss See cases [RCV000143623] Chr10:123986772..133613639 [GRCh38]
Chr10:125746288..135427143 [GRCh37]
Chr10:125736278..135277133 [NCBI36]
Chr10:10q26.13-26.3
pathogenic
GRCh38/hg38 10q26.13-26.3(chr10:123576393-133613639)x1 copy number loss See cases [RCV000143544] Chr10:123576393..133613639 [GRCh38]
Chr10:125335909..135427143 [GRCh37]
Chr10:125325899..135277133 [NCBI36]
Chr10:10q26.13-26.3
pathogenic
GRCh38/hg38 10q26.2-26.3(chr10:126794646-133613639)x1 copy number loss See cases [RCV000143615] Chr10:126794646..133613639 [GRCh38]
Chr10:128483215..135427143 [GRCh37]
Chr10:128473205..135277133 [NCBI36]
Chr10:10q26.2-26.3
pathogenic
GRCh37/hg19 10q26.13-26.3(chr10:123731209-135353867)x1 copy number loss See cases [RCV000203440] Chr10:123731209..135353867 [GRCh37]
Chr10:10q26.13-26.3
pathogenic|likely pathogenic
GRCh37/hg19 10q24.32-26.3(chr10:103288313-135512075)x3 copy number gain See cases [RCV000240457] Chr10:103288313..135512075 [GRCh37]
Chr10:10q24.32-26.3
pathogenic
GRCh37/hg19 10q26.12-26.3(chr10:122125760-135062972)x3 copy number gain See cases [RCV000449169] Chr10:122125760..135062972 [GRCh37]
Chr10:10q26.12-26.3
likely pathogenic
GRCh37/hg19 10q26.13-26.3(chr10:124147428-135370736)x1 copy number loss See cases [RCV000449336] Chr10:124147428..135370736 [GRCh37]
Chr10:10q26.13-26.3
pathogenic
GRCh37/hg19 10q24.32-26.3(chr10:104633712-135427143)x3 copy number gain See cases [RCV000449386] Chr10:104633712..135427143 [GRCh37]
Chr10:10q24.32-26.3
pathogenic
GRCh37/hg19 10q26.12-26.3(chr10:122343861-135427143)x1 copy number loss See cases [RCV000446095] Chr10:122343861..135427143 [GRCh37]
Chr10:10q26.12-26.3
pathogenic
GRCh37/hg19 10q24.2-26.3(chr10:100780957-135427143)x3 copy number gain See cases [RCV000446733] Chr10:100780957..135427143 [GRCh37]
Chr10:10q24.2-26.3
pathogenic
GRCh37/hg19 10q26.2-26.3(chr10:128465436-135427143)x1 copy number loss See cases [RCV000447132] Chr10:128465436..135427143 [GRCh37]
Chr10:10q26.2-26.3
pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:93297-135378918)x3 copy number gain See cases [RCV000448750] Chr10:93297..135378918 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10q26.2-26.3(chr10:129825453-135427143)x1 copy number loss See cases [RCV000511570] Chr10:129825453..135427143 [GRCh37]
Chr10:10q26.2-26.3
likely pathogenic
GRCh37/hg19 10q26.2-26.3(chr10:127658004-135427143)x1 copy number loss See cases [RCV000511813] Chr10:127658004..135427143 [GRCh37]
Chr10:10q26.2-26.3
pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143) copy number gain See cases [RCV000511389] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic|uncertain significance
GRCh37/hg19 10q25.1-26.3(chr10:106003533-135427143)x3 copy number gain See cases [RCV000510813] Chr10:106003533..135427143 [GRCh37]
Chr10:10q25.1-26.3
pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143)x3 copy number gain See cases [RCV000510861] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10q23.32-26.3(chr10:93283493-135427143)x3 copy number gain See cases [RCV000510972] Chr10:93283493..135427143 [GRCh37]
Chr10:10q23.32-26.3
pathogenic
GRCh37/hg19 10q26.3(chr10:130693843-134772865)x1 copy number loss See cases [RCV000511280] Chr10:130693843..134772865 [GRCh37]
Chr10:10q26.3
likely pathogenic
GRCh37/hg19 10q11.21-26.3(chr10:42347406-135534747)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626438] Chr10:42347406..135534747 [GRCh37]
Chr10:10q11.21-26.3
drug response
GRCh37/hg19 10q26.2-26.3(chr10:129007673-135427143)x3 copy number gain See cases [RCV000512398] Chr10:129007673..135427143 [GRCh37]
Chr10:10q26.2-26.3
pathogenic
GRCh37/hg19 10q26.13-26.3(chr10:127375792-135427143)x1 copy number loss not provided [RCV000683283] Chr10:127375792..135427143 [GRCh37]
Chr10:10q26.13-26.3
pathogenic
GRCh37/hg19 10q26.11-26.3(chr10:121269222-135427143)x3 copy number gain not provided [RCV000683288] Chr10:121269222..135427143 [GRCh37]
Chr10:10q26.11-26.3
pathogenic
GRCh37/hg19 10q26.13-26.3(chr10:125450893-135427143)x1 copy number loss not provided [RCV000683285] Chr10:125450893..135427143 [GRCh37]
Chr10:10q26.13-26.3
pathogenic
GRCh37/hg19 10q24.33-26.3(chr10:105613040-135427143)x3 copy number gain not provided [RCV000683290] Chr10:105613040..135427143 [GRCh37]
Chr10:10q24.33-26.3
pathogenic
GRCh37/hg19 10q26.12-26.3(chr10:123019239-135427143)x1 copy number loss not provided [RCV000683286] Chr10:123019239..135427143 [GRCh37]
Chr10:10q26.12-26.3
pathogenic
GRCh37/hg19 10q26.12-26.3(chr10:122509781-135427143)x1 copy number loss not provided [RCV000683287] Chr10:122509781..135427143 [GRCh37]
Chr10:10q26.12-26.3
pathogenic
GRCh37/hg19 10q26.3(chr10:131949020-135427143)x1 copy number loss not provided [RCV000683274] Chr10:131949020..135427143 [GRCh37]
Chr10:10q26.3
pathogenic
GRCh37/hg19 10q23.33-26.3(chr10:94346520-135427143)x3 copy number gain not provided [RCV000683291] Chr10:94346520..135427143 [GRCh37]
Chr10:10q23.33-26.3
pathogenic
GRCh37/hg19 10q26.12-26.3(chr10:122443197-135477883)x1 copy number loss not provided [RCV000737305] Chr10:122443197..135477883 [GRCh37]
Chr10:10q26.12-26.3
pathogenic
GRCh37/hg19 10q26.2-26.3(chr10:129454892-135447971)x1 copy number loss not provided [RCV000737323] Chr10:129454892..135447971 [GRCh37]
Chr10:10q26.2-26.3
pathogenic
GRCh37/hg19 10q26.2-26.3(chr10:129830593-132635031)x1 copy number loss not provided [RCV000737325] Chr10:129830593..132635031 [GRCh37]
Chr10:10q26.2-26.3
benign
GRCh37/hg19 10q26.3(chr10:131807625-132220631)x3 copy number gain not provided [RCV000749844] Chr10:131807625..132220631 [GRCh37]
Chr10:10q26.3
benign
GRCh37/hg19 10p15.3-q26.3(chr10:73232-135524321)x3 copy number gain not provided [RCV000749464] Chr10:73232..135524321 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:98087-135477883)x3 copy number gain not provided [RCV000749465] Chr10:98087..135477883 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10q26.2-26.3(chr10:129381095-135427143)x1 copy number loss not provided [RCV001006364] Chr10:129381095..135427143 [GRCh37]
Chr10:10q26.2-26.3
pathogenic
GRCh37/hg19 10q25.1-26.3(chr10:110022170-135439095) copy number gain not provided [RCV000767665] Chr10:110022170..135439095 [GRCh37]
Chr10:10q25.1-26.3
pathogenic
GRCh37/hg19 10q26.13-26.3(chr10:124988334-135427143)x3 copy number gain not provided [RCV000848791] Chr10:124988334..135427143 [GRCh37]
Chr10:10q26.13-26.3
pathogenic
GRCh37/hg19 10q26.2-26.3(chr10:129009772-135427143)x1 copy number loss not provided [RCV001006362] Chr10:129009772..135427143 [GRCh37]
Chr10:10q26.2-26.3
pathogenic
GRCh37/hg19 10q25.2-26.3(chr10:114544537-135427143)x3 copy number gain not provided [RCV000847820] Chr10:114544537..135427143 [GRCh37]
Chr10:10q25.2-26.3
pathogenic
GRCh37/hg19 10q26.3(chr10:131759691-133023235)x3 copy number gain not provided [RCV001006367] Chr10:131759691..133023235 [GRCh37]
Chr10:10q26.3
uncertain significance
NM_006541.5(GLRX3):c.492G>A (p.Gln164=) single nucleotide variant not provided [RCV000951113] Chr10:130166520 [GRCh38]
Chr10:131964784 [GRCh37]
Chr10:10q26.3
benign
GRCh37/hg19 10q26.11-26.3(chr10:119996339-135427143)x3 copy number gain not provided [RCV001006356] Chr10:119996339..135427143 [GRCh37]
Chr10:10q26.11-26.3
pathogenic
GRCh37/hg19 10q25.3-26.3(chr10:118247181-135435319)x3 copy number gain not provided [RCV001537903] Chr10:118247181..135435319 [GRCh37]
Chr10:10q25.3-26.3
pathogenic
NC_000010.10:g.129942146_132848717del deletion Paroxysmal dyskinesia [RCV001003862] Chr10:129942146..132848717 [GRCh37]
Chr10:10q26.2-26.3
likely pathogenic
GRCh37/hg19 10q26.3(chr10:131243689-132131959)x3,4 copy number gain not provided [RCV001594474] Chr10:131243689..132131959 [GRCh37]
Chr10:10q26.3
uncertain significance
GRCh37/hg19 10q26.2-26.3(chr10:129605105-135427143)x1 copy number loss See cases [RCV002285041] Chr10:129605105..135427143 [GRCh37]
Chr10:10q26.2-26.3
pathogenic
GRCh37/hg19 10q26.2-26.3(chr10:129031265-135427143)x1 copy number loss not provided [RCV001259085] Chr10:129031265..135427143 [GRCh37]
Chr10:10q26.2-26.3
pathogenic
GRCh37/hg19 10q26.2-26.3(chr10:129483682-135434178) copy number loss Global developmental delay [RCV001352664] Chr10:129483682..135434178 [GRCh37]
Chr10:10q26.2-26.3
pathogenic
Single allele deletion Distal 10q deletion syndrome [RCV001391670] Chr10:127548166..135440251 [GRCh37]
Chr10:10q26.2-26.3
pathogenic
GRCh37/hg19 10q26.3(chr10:131542049-132107231)x1 copy number loss not provided [RCV001594473] Chr10:131542049..132107231 [GRCh37]
Chr10:10q26.3
pathogenic
GRCh37/hg19 10q26.12-26.3(chr10:122785023-135457222)x1 copy number loss See cases [RCV001526488] Chr10:122785023..135457222 [GRCh37]
Chr10:10q26.12-26.3
pathogenic
GRCh37/hg19 10q25.1-26.3(chr10:108455687-135427143) copy number gain not specified [RCV002052891] Chr10:108455687..135427143 [GRCh37]
Chr10:10q25.1-26.3
pathogenic
GRCh37/hg19 10q26.12-26.3(chr10:122125760-135062972) copy number gain not specified [RCV002052894] Chr10:122125760..135062972 [GRCh37]
Chr10:10q26.12-26.3
likely pathogenic
GRCh37/hg19 10q26.12-26.3(chr10:122343861-135427143) copy number loss not specified [RCV002052895] Chr10:122343861..135427143 [GRCh37]
Chr10:10q26.12-26.3
pathogenic
GRCh37/hg19 10q26.2-26.3(chr10:128465436-135427143) copy number loss not specified [RCV002052902] Chr10:128465436..135427143 [GRCh37]
Chr10:10q26.2-26.3
pathogenic
GRCh37/hg19 10q26.2-26.3(chr10:129914228-135427143) copy number loss not specified [RCV002052908] Chr10:129914228..135427143 [GRCh37]
Chr10:10q26.2-26.3
pathogenic
GRCh37/hg19 10q26.3(chr10:131324081-132362298) copy number gain not specified [RCV002052909] Chr10:131324081..132362298 [GRCh37]
Chr10:10q26.3
uncertain significance
GRCh37/hg19 10q26.13-26.3(chr10:127198625-135427143)x3 copy number gain See cases [RCV002292400] Chr10:127198625..135427143 [GRCh37]
Chr10:10q26.13-26.3
pathogenic
GRCh37/hg19 10q26.13-26.3(chr10:126914469-135427143)x1 copy number loss See cases [RCV002292397] Chr10:126914469..135427143 [GRCh37]
Chr10:10q26.13-26.3
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:15987 AgrOrtholog
COSMIC GLRX3 COSMIC
Ensembl Genes ENSG00000108010 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSP00000330836 ENTREZGENE
  ENSP00000330836.5 UniProtKB/Swiss-Prot
  ENSP00000357633 ENTREZGENE
  ENSP00000357633.1 UniProtKB/Swiss-Prot
  ENSP00000435445.1 UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000331244 ENTREZGENE
  ENST00000331244.10 UniProtKB/Swiss-Prot
  ENST00000368644 ENTREZGENE
  ENST00000368644.5 UniProtKB/Swiss-Prot
  ENST00000481034.1 UniProtKB/Swiss-Prot
GTEx ENSG00000108010 GTEx
HGNC ID HGNC:15987 ENTREZGENE
Human Proteome Map GLRX3 Human Proteome Map
InterPro Glutaredoxin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GRX_PICOT-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Monothiol_GRX-rel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:10539 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 10539 ENTREZGENE
OMIM 612754 OMIM
PANTHER PTHR10293 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Glutaredoxin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA162389829 PharmGKB
PROSITE GLUTAREDOXIN_2 UniProtKB/Swiss-Prot
  THIOREDOXIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs TIGR00365 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A140VJK1 ENTREZGENE, UniProtKB/TrEMBL
  GLRX3_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q9P1B1 ENTREZGENE
UniProt Secondary B3KMP7 UniProtKB/Swiss-Prot
  B3KMQ5 UniProtKB/Swiss-Prot
  D3DRG2 UniProtKB/Swiss-Prot
  Q5JV01 UniProtKB/Swiss-Prot
  Q96CE0 UniProtKB/Swiss-Prot
  Q9P1B0 UniProtKB/Swiss-Prot
  Q9P1B1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-14 GLRX3  glutaredoxin 3  TXNL3  thioredoxin-like 3  Data Merged 737654 PROVISIONAL
2011-07-27 GLRX3  glutaredoxin 3  GLRX3  glutaredoxin 3  Symbol and/or name change 5135510 APPROVED