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Gene: Rasgrf2 (RAS protein-specific guanine nucleotide-releasing factor 2) Mus musculus
Symbol: Rasgrf2
Name: RAS protein-specific guanine nucleotide-releasing factor 2
Description: Predicted to have Ras guanyl-nucleotide exchange factor activity. Involved in long-term synaptic potentiation and regulation of NMDA receptor activity. Predicted to localize to endoplasmic reticulum. Is expressed in brain; hypothalamus mantle layer; medulla oblongata basal plate mantle layer; and pons mantle layer. Orthologous to human RASGRF2 (Ras protein specific guanine nucleotide releasing factor 2); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH 1,1-dichloroethene; 3,4-methylenedioxymethamphetamine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6330417G04Rik; AW048350; Grf2; guanine nucleotide releasing factor; guanine nucleotide-releasing factor 2; ras guanine nucleotide exchange factor 2; Ras-GRF2; ras-specific guanine nucleotide-releasing factor 2; RIKEN cDNA 6330417G04 gene
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
NCBI Annotation Information: Annotation category: partial on reference assembly
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1391,880,400 - 92,131,656 (-)EnsemblGRCm38mm10GRCm38
GRCm381391,880,407 - 92,131,828 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371392,792,695 - 92,901,449 (-)NCBIGRCm37mm9NCBIm37
MGSCv371392,020,012 - 92,127,647 (-)NCBIGRCm37mm9NCBIm37
MGSCv361392,358,671 - 92,462,280 (-)NCBImm8
Celera1395,507,627 - 95,744,228 (-)NCBICelera
Cytogenetic Map13C3NCBI
cM Map1347.43NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Rasgrf2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69461
Created: 2001-11-27
Species: Mus musculus
Last Modified: 2020-07-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.