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Gene: AKAP6 (A-kinase anchoring protein 6) Homo sapiens
Symbol: AKAP6
Name: A-kinase anchoring protein 6
Description: Exhibits ion channel binding activity. Involved in cellular response to cAMP; positive regulation of delayed rectifier potassium channel activity; and regulation of membrane repolarization. Localizes to several cellular components, including the calcium channel complex; perinuclear region of cytoplasm; and sarcoplasmic reticulum. Implicated in anorexia nervosa and ovary epithelial cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A kinase (PRKA) anchor protein 6; A-kinase anchor protein 100 kDa; A-kinase anchor protein 6; ADAP100; ADAP6; AKAP 100; AKAP-6; AKAP100; KIAA0311; mAKAP; MGC165020; PRKA6; protein kinase A anchoring protein 6; protein kinase A-anchoring protein 6
Mus musculus (house mouse) : Akap6 (A kinase (PRKA) anchor protein 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Akap6 (A-kinase anchoring protein 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Akap6 (A-kinase anchoring protein 6)
Pan paniscus (bonobo/pygmy chimpanzee) : AKAP6 (A-kinase anchoring protein 6)
Canis lupus familiaris (dog) : AKAP6 (A-kinase anchoring protein 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Akap6 (A-kinase anchoring protein 6)
Sus scrofa (pig) : AKAP6 (A-kinase anchoring protein 6)
Chlorocebus sabaeus (green monkey) : AKAP6 (A-kinase anchoring protein 6)
Heterocephalus glaber (naked mole-rat) : Akap6 (A-kinase anchoring protein 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1432,329,298 - 32,837,684 (+)Ensembl
GRCh381432,203,610 - 32,837,684 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371432,798,479 - 33,302,268 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361431,868,274 - 32,372,018 (+)NCBINCBI36hg18NCBI36
Build 341431,868,273 - 32,372,018NCBI
Celera1412,665,076 - 13,167,767 (+)NCBI
Cytogenetic Map14q12NCBI
HuRef1412,916,606 - 13,419,742 (+)NCBIHuRef
CHM1_11432,798,120 - 33,300,973 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on AKAP6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69458
Created: 2001-11-27
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.