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Gene: CLIP1 (CAP-Gly domain containing linker protein 1) Homo sapiens
Symbol: CLIP1
Name: CAP-Gly domain containing linker protein 1
Description: Exhibits identical protein binding activity; microtubule plus-end binding activity; and zinc ion binding activity. Involved in microtubule bundle formation and positive regulation of microtubule polymerization. Localizes to centrosome and microtubule. Colocalizes with macropinosome and microtubule plus-end.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CAP-Gly domain-containing linker protein 1; CLIP; CLIP-170; CLIP170; CYLN1; cytoplasmic linker 1; cytoplasmic linker protein 1; cytoplasmic linker protein 170 alpha-2; cytoplasmic linker protein CLIP-170; MGC131604; Reed-Steinberg cell-expressed intermediate filament-associated protein; reed-Sternberg intermediate filament-associated protein; restin; restin (Reed-Steinberg cell-expressed intermediate filament-associated protein); RSN
Mus musculus (house mouse) : Clip1 (CAP-GLY domain containing linker protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Clip1 (CAP-GLY domain containing linker protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clip1 (CAP-Gly domain containing linker protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CLIP1 (CAP-Gly domain containing linker protein 1)
Canis lupus familiaris (dog) : CLIP1 (CAP-Gly domain containing linker protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clip1 (CAP-Gly domain containing linker protein 1)
Sus scrofa (pig) : CLIP1 (CAP-Gly domain containing linker protein 1)
Chlorocebus sabaeus (African green monkey) : CLIP1 (CAP-Gly domain containing linker protein 1)
Heterocephalus glaber (naked mole-rat) : Clip1 (CAP-Gly domain containing linker protein 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl12122,271,432 - 122,422,632 (-)EnsemblGRCh38hg38GRCh38
GRCh3812122,271,431 - 122,422,956 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712122,755,981 - 122,907,179 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612121,321,934 - 121,473,069 (-)NCBINCBI36hg18NCBI36
Build 3412121,280,860 - 121,431,996NCBI
Celera12122,346,248 - 122,498,975 (-)NCBI
Cytogenetic Map12q24.31NCBI
HuRef12119,716,905 - 119,868,164 (-)NCBIHuRef
CHM1_112122,724,274 - 122,875,405 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CLIP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69221
Created: 2001-11-14
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.