Msmb (beta-microseminoprotein) - Rat Genome Database

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Gene: Msmb (beta-microseminoprotein) Mus musculus
Analyze
Symbol: Msmb
Name: beta-microseminoprotein
RGD ID: 69209
MGI Page MGI
Description: Predicted to be located in extracellular region. Is expressed in male reproductive gland or organ. Used to study prostate cancer. Orthologous to human MSMB (microseminoprotein beta).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: beta-; beta-inhibin; beta-MSP; PIP; prostate secreted seminal plasma protein; prostate secretory protein of 94 amino acids; prostatic inhibin protein; PS; PSP-94; PSP94
RGD Orthologs
Human
Rat
Bonobo
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391431,863,980 - 31,880,284 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1431,863,980 - 31,880,327 (+)EnsemblGRCm39 Ensembl
GRCm381432,142,023 - 32,158,327 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1432,142,023 - 32,158,370 (+)EnsemblGRCm38mm10GRCm38
MGSCv371432,955,209 - 32,971,513 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361430,971,064 - 30,987,336 (+)NCBIMGSCv36mm8
Celera1428,400,862 - 28,417,156 (+)NCBICelera
Cytogenetic Map14BNCBI
cM Map1419.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1783399   PMID:9560157   PMID:10025505   PMID:12616537   PMID:12706823   PMID:14610273   PMID:15674347   PMID:15727931   PMID:16278416   PMID:16397079   PMID:16751981   PMID:17189386  
PMID:18371946   PMID:21267068   PMID:24194600   PMID:25938513   PMID:27879271  


Genomics

Comparative Map Data
Msmb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391431,863,980 - 31,880,284 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1431,863,980 - 31,880,327 (+)EnsemblGRCm39 Ensembl
GRCm381432,142,023 - 32,158,327 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1432,142,023 - 32,158,370 (+)EnsemblGRCm38mm10GRCm38
MGSCv371432,955,209 - 32,971,513 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361430,971,064 - 30,987,336 (+)NCBIMGSCv36mm8
Celera1428,400,862 - 28,417,156 (+)NCBICelera
Cytogenetic Map14BNCBI
cM Map1419.4NCBI
MSMB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381046,033,313 - 46,046,269 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1046,033,307 - 46,048,180 (-)EnsemblGRCh38hg38GRCh38
GRCh371051,549,553 - 51,562,509 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361051,219,559 - 51,232,601 (+)NCBINCBI36Build 36hg18NCBI36
Build 341051,219,558 - 51,232,596NCBI
Celera1042,850,152 - 42,863,194 (+)NCBICelera
Cytogenetic Map10q11.22NCBI
HuRef1045,657,010 - 45,669,884 (+)NCBIHuRef
CHM1_11051,831,488 - 51,844,455 (+)NCBICHM1_1
T2T-CHM13v2.01046,914,187 - 46,927,144 (-)NCBIT2T-CHM13v2.0
Msmb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8167,372,803 - 7,393,406 (+)NCBIGRCr8
mRatBN7.2167,366,536 - 7,387,124 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl167,366,536 - 7,387,123 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx167,379,294 - 7,399,645 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0168,524,149 - 8,544,500 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0167,377,390 - 7,397,893 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0168,280,275 - 8,300,853 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl168,280,275 - 8,300,852 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0168,197,305 - 8,217,886 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4167,619,432 - 7,640,019 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1167,619,429 - 7,640,016 (+)NCBI
Celera167,811,293 - 7,831,868 (-)NCBICelera
Cytogenetic Map16p16NCBI
MSMB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2858,912,198 - 58,925,192 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11058,917,516 - 58,930,510 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01043,187,155 - 43,200,150 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11046,449,077 - 46,462,065 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1046,449,079 - 46,464,007 (-)Ensemblpanpan1.1panPan2
Msmb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721379,151,913 - 79,171,876 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936728354,769 - 374,696 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MSMB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1490,533,103 - 90,582,765 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11490,533,092 - 90,542,309 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21498,575,637 - 98,584,876 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MSMB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1941,796,948 - 41,810,373 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl941,803,922 - 41,810,276 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660481,506,813 - 1,519,452 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Msmb
579 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:170
Count of miRNA genes:79
Interacting mature miRNAs:84
Transcripts:ENSMUST00000022464, ENSMUST00000130397
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301991Wta3_mweight adult 3 (mouse)Not determined14388747337887650Mouse
4141550Dbm3_mdiabetes modifier 3 (mouse)Not determined514347339143596Mouse
4141864Mrdq4_mmodifier of retinal degeneration QTL 4 (mouse)Not determined992324548765082Mouse
1300779Dyscalc4_mdystrophic cardiac calcinosis 4 (mouse)Not determined141221287146213007Mouse
27226748Femd8_mfemur midshaft diameter 8, 10 week (mouse)141376927346737457Mouse
27226752Femd4_mfemur midshaft diameter 4, 5 week (mouse)141376927347237457Mouse
1300544Hypn_mhyperinsulinemia (mouse)Not determined141516061649160765Mouse
1301372Sluc13_msusceptibility to lung cancer 13 (mouse)Not determined141882760452827726Mouse
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142106245071885801Mouse
14746973Manh76_mmandible shape 76 (mouse)142228721756287217Mouse
4142485Modor2_mmodifier of ocular retardation 2 (mouse)Not determined142492624858179769Mouse
13506929Recrq10_mrecombination rate in male meiosis QTL 10 (mouse)142792195761137449Mouse
10043886Cia49_mcollagen induced arthritis QTL 49 (mouse)Not determined142999699463997133Mouse
27226775Tibl7_mtibia length 7, 5 week (mouse)143032195748837457Mouse
27226744Metcl6_mmetatarsal-calcaneal length 6, 5 week (mouse)143032195752937457Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143032195787937436Mouse
1300909Ath13_matherosclerosis 13 (mouse)Not determined143033525064335381Mouse
1300998Cia17_mcollagen induced arthritis 17 (mouse)Not determined143033525064335381Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000022464   ⟹   ENSMUSP00000022464
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1431,863,980 - 31,880,324 (+)Ensembl
GRCm38.p6 Ensembl1432,142,023 - 32,158,367 (+)Ensembl
RefSeq Acc Id: ENSMUST00000130397
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1431,869,544 - 31,880,327 (+)Ensembl
GRCm38.p6 Ensembl1432,147,587 - 32,158,370 (+)Ensembl
RefSeq Acc Id: NM_020597   ⟹   NP_065622
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391431,863,980 - 31,880,284 (+)NCBI
GRCm381432,142,023 - 32,158,327 (+)NCBI
MGSCv371432,955,209 - 32,971,513 (+)RGD
Celera1428,400,862 - 28,417,156 (+)RGD
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017315907   ⟹   XP_017171396
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391431,867,337 - 31,880,264 (+)NCBI
GRCm381432,145,380 - 32,158,307 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_065622 (Get FASTA)   NCBI Sequence Viewer  
  XP_017171396 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB49683 (Get FASTA)   NCBI Sequence Viewer  
  EDL24829 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000022464
  ENSMUSP00000022464.7
GenBank Protein O08540 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_065622   ⟸   NM_020597
- Peptide Label: precursor
- UniProtKB: O08540 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017171396   ⟸   XM_017315907
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000022464   ⟸   ENSMUST00000022464

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O08540-F1-model_v2 AlphaFold O08540 1-113 view protein structure

Promoters
RGD ID:8681852
Promoter ID:EPDNEW_M18957
Type:single initiation site
Name:Msmb_1
Description:Mus musculus beta-microseminoprotein , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381432,142,023 - 32,142,083EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97166 AgrOrtholog
Ensembl Genes ENSMUSG00000021907 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000022464 ENTREZGENE
  ENSMUST00000022464.14 UniProtKB/Swiss-Prot
Gene3D-CATH 2.20.25.590 UniProtKB/Swiss-Prot
  Complement Module, domain 1 UniProtKB/Swiss-Prot
InterPro PSP94 UniProtKB/Swiss-Prot
KEGG Report mmu:17695 UniProtKB/Swiss-Prot
MGD MGI:97166 ENTREZGENE
NCBI Gene 17695 ENTREZGENE
PANTHER BETA-MICROSEMINOPROTEIN UniProtKB/Swiss-Prot
  PTHR10500 UniProtKB/Swiss-Prot
Pfam PSP94 UniProtKB/Swiss-Prot
PhenoGen Msmb PhenoGen
UniProt MSMB_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE