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Gene: a (nonagouti) Mus musculus
Symbol: a
Name: nonagouti
Description: Exhibits type 3 melanocortin receptor binding activity and type 4 melanocortin receptor binding activity. Involved in several processes, including adult feeding behavior; melanosome transport; and positive regulation of melanin biosynthetic process. Used to study obesity and type 2 diabetes mellitus. Is expressed in hair bulb and skin. Orthologous to human ASIP (agouti signaling protein); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; melanocortin system pathway; INTERACTS WITH 1,2-dichloroethane; 7,12-dimethyltetraphene; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A; agouti coat color protein; agouti signal protein; agouti switch protein; agouti-signaling protein; As; ASIP; ASP; non-agouti
Homo sapiens (human) : ASIP (agouti signaling protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Asip (agouti signaling protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Asip (agouti signaling protein)
Pan paniscus (bonobo/pygmy chimpanzee) : ASIP (agouti signaling protein)
Canis lupus familiaris (dog) : ASIP (agouti signaling protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Asip (agouti signaling protein)
Sus scrofa (pig) : ASIP (agouti signaling protein)
Chlorocebus sabaeus (African green monkey) : ASIP (agouti signaling protein)
Heterocephalus glaber (naked mole-rat) : Asip (agouti signaling protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl2155,018,266 - 155,027,104 (+)EnsemblGRCm38mm10GRCm38
GRCm38 Ensembl2154,791,402 - 155,051,012 (+)EnsemblGRCm38mm10GRCm38
GRCm382154,950,599 - 155,051,012 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372154,839,306 - 154,876,748 (+)NCBIGRCm37mm9NCBIm37
MGSCv362154,705,018 - 154,742,423 (+)NCBImm8
Celera2160,940,588 - 160,977,934 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map276.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69200
Created: 2001-11-13
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.