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Gene: Osm (oncostatin M) Mus musculus
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Symbol: Osm
Name: oncostatin M
RGD ID: 69135
Description: Exhibits cytokine activity. Involved in several processes, including behavioral response to pain; positive regulation of peptidyl-tyrosine phosphorylation; and tyrosine phosphorylation of STAT protein. Predicted to localize to extracellular space. Is expressed in dorsal aorta; future spinal cord; genitourinary system; liver; and submandibular gland. Orthologous to human OSM (oncostatin M); PARTICIPATES IN granulocyte-macrophage colony-stimulating factor signaling pathway; interleukin-3 signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 4-(ethoxymethylene)-2-phenyloxazol-5-one; 4-hydroxynon-2-enal.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: On; OncoM; oncostatin-M
Orthologs:
Homo sapiens (human) : OSM (oncostatin M)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Osm (oncostatin M)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Osm (oncostatin M)
Pan paniscus (bonobo/pygmy chimpanzee) : OSM (oncostatin M)
Canis lupus familiaris (dog) : OSM (oncostatin M)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Osm (oncostatin M)
Sus scrofa (pig) : OSM (oncostatin M)
Chlorocebus sabaeus (African green monkey) : OSM (oncostatin M)
Heterocephalus glaber (naked mole-rat) : Osm (oncostatin M)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl114,236,420 - 4,241,026 (+)EnsemblGRCm38mm10GRCm38
GRCm38114,236,785 - 4,241,026 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37114,136,788 - 4,141,029 (+)NCBIGRCm37mm9NCBIm37
MGSCv36114,136,423 - 4,141,029 (+)NCBImm8
Celera114,735,950 - 4,740,191 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map112.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Osm
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69135
Created: 2001-11-08
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.