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Gene: Osm (oncostatin M) Mus musculus
Symbol: Osm
Name: oncostatin M
RGD ID: 69135
Description: Exhibits cytokine activity. Involved in several processes, including behavioral response to pain; positive regulation of peptidyl-tyrosine phosphorylation; and tyrosine phosphorylation of STAT protein. Predicted to localize to extracellular space. Is expressed in dorsal aorta; future spinal cord; genitourinary system; liver; and submandibular gland. Orthologous to human OSM (oncostatin M); PARTICIPATES IN granulocyte-macrophage colony-stimulating factor signaling pathway; interleukin-3 signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 4-(ethoxymethylene)-2-phenyloxazol-5-one; 4-hydroxynon-2-enal.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: On; OncoM; oncostatin-M
Homo sapiens (human) : OSM (oncostatin M)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Osm (oncostatin M)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Osm (oncostatin M)
Pan paniscus (bonobo/pygmy chimpanzee) : OSM (oncostatin M)
Canis lupus familiaris (dog) : OSM (oncostatin M)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Osm (oncostatin M)
Sus scrofa (pig) : OSM (oncostatin M)
Chlorocebus sabaeus (African green monkey) : OSM (oncostatin M)
Heterocephalus glaber (naked mole-rat) : Osm (oncostatin M)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl114,236,420 - 4,241,026 (+)EnsemblGRCm38mm10GRCm38
GRCm38114,236,785 - 4,241,026 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37114,136,788 - 4,141,029 (+)NCBIGRCm37mm9NCBIm37
MGSCv36114,136,423 - 4,141,029 (+)NCBImm8
Celera114,735,950 - 4,740,191 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map112.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Osm
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69135
Created: 2001-11-08
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.