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Gene: MATK (megakaryocyte-associated tyrosine kinase) Homo sapiens
Symbol: MATK
Name: megakaryocyte-associated tyrosine kinase
Description: Predicted to have protein tyrosine kinase activity. Predicted to be involved in ERBB2 signaling pathway; positive regulation of cell population proliferation; and protein phosphorylation. Predicted to localize to cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CHK; CSK homologous kinase; Csk-homologous kinase; Csk-type protein tyrosine kinase; CTK; DKFZp434N1212; hematopoietic consensus tyrosine-lacking kinase; HHYLTK; hydroxyaryl-protein kinase; HYL; HYL tyrosine kinase; HYLTK; leukocyte carboxyl-terminal src kinase related; Lsk; megakaryocyte-associated tyrosine-protein kinase; MGC1708; MGC2101; protein kinase HYL; tyrosine kinase MATK; tyrosine-protein kinase CTK; tyrosylprotein kinase
Mus musculus (house mouse) : Matk (megakaryocyte-associated tyrosine kinase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Matk (megakaryocyte-associated tyrosine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Matk (megakaryocyte-associated tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : MATK (megakaryocyte-associated tyrosine kinase)
Canis lupus familiaris (dog) : MATK (megakaryocyte-associated tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Matk (megakaryocyte-associated tyrosine kinase)
Sus scrofa (pig) : MATK (megakaryocyte-associated tyrosine kinase)
Chlorocebus sabaeus (African green monkey) : MATK (megakaryocyte-associated tyrosine kinase)
Heterocephalus glaber (naked mole-rat) : Matk (megakaryocyte-associated tyrosine kinase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl193,777,970 - 3,802,129 (-)EnsemblGRCh38hg38GRCh38
GRCh38193,777,973 - 3,801,799 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37193,777,967 - 3,801,810 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36193,728,967 - 3,752,810 (-)NCBINCBI36hg18NCBI36
Build 34193,728,967 - 3,737,414NCBI
Celera193,715,610 - 3,739,451 (-)NCBI
Cytogenetic Map19p13.3NCBI
HuRef193,542,732 - 3,566,615 (-)NCBIHuRef
CHM1_1193,777,602 - 3,801,471 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MATK
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69108
Created: 2001-11-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.