Nos3<sup>em13Mcwi</sup> (nitric oxide synthase 3, endothelial cell; zinc finger nuclease induced mutant 13, Medical College of Wisconsin) - Rat Genome Database

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Gene: Nos3em13Mcwi (nitric oxide synthase 3, endothelial cell; zinc finger nuclease induced mutant 13, Medical College of Wisconsin) Rattus norvegicus
Analyze
Symbol: Nos3em13Mcwi
Name: nitric oxide synthase 3, endothelial cell; zinc finger nuclease induced mutant 13, Medical College of Wisconsin
RGD ID: 6893422
Description: This allele was made by ZFN mutagenesis. The resulting mutation is a 165-bp deletion including part of exon 3, intron 3, and part of exon 4.
Type: allele  of Nos3  
Previously known as: Nos3^[em13Mcwi]; Nos3em13Mcwi
Is Marker For: Strains:   SS-Nos3em13Mcwi  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Cytogenetic Map4 RGD


References

References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. PhysGen Knockouts PhysGen Knockout strains

Genomics

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Nos3em13Mcwi-var1 chr4 10811102 10811266 CTGCTCATGAGCCTGGGAA CCACTCCTGGGGAGAGGAGAGGGCCACAAGCCTTGGCGTCAGGATGGTGAAAGGGCTGGGGAATGAGGTGATCTGAAGGC TCCTCCACTCAGGGTGAGGGTGTTGGGAGGAGCAGGGGAGACCCACCTTTTGATCGAGTTATAGTA - deletion mRatBN7.2

Related Rat Strains
The following Strains have been annotated to Nos3em13Mcwi
SS-Nos3em13Mcwi    


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_021838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles


Additional Information