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Gene: PDGFC (platelet derived growth factor C) Homo sapiens
Symbol: PDGFC
Name: platelet derived growth factor C
Description: Exhibits platelet-derived growth factor receptor binding activity and protein homodimerization activity. Involved in platelet-derived growth factor receptor signaling pathway and positive regulation of fibroblast proliferation. Localizes to several cellular components, including cell surface; cytosol; and extracellular space.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FALLOTEIN; PDGF-C; platelet-derived growth factor C; SCDGF; secretory growth factor-like protein; spinal cord-derived growth factor; VEGF-E
Mus musculus (house mouse) : Pdgfc (platelet-derived growth factor, C polypeptide)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pdgfc (platelet derived growth factor C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdgfc (platelet derived growth factor C)
Pan paniscus (bonobo/pygmy chimpanzee) : PDGFC (platelet derived growth factor C)
Canis lupus familiaris (dog) : PDGFC (platelet derived growth factor C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdgfc (platelet derived growth factor C)
Sus scrofa (pig) : PDGFC (platelet derived growth factor C)
Chlorocebus sabaeus (African green monkey) : PDGFC (platelet derived growth factor C)
Heterocephalus glaber (naked mole-rat) : Pdgfc (platelet derived growth factor C)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl4156,760,454 - 156,971,799 (-)EnsemblGRCh38hg38GRCh38
GRCh384156,760,454 - 156,971,799 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh374157,682,763 - 157,892,546 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364157,902,214 - 158,111,996 (-)NCBINCBI36hg18NCBI36
Build 344158,040,368 - 158,250,151NCBI
Celera4155,025,774 - 155,235,563 (-)NCBI
Cytogenetic Map4q32.1NCBI
HuRef4153,433,623 - 153,643,623 (-)NCBIHuRef
CHM1_14157,660,122 - 157,869,922 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on PDGFC
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68605
Created: 2001-07-11
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.