Scamp2 (secretory carrier membrane protein 2) - Rat Genome Database

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Gene: Scamp2 (secretory carrier membrane protein 2) Mus musculus
Analyze
Symbol: Scamp2
Name: secretory carrier membrane protein 2
RGD ID: 68491
MGI Page MGI
Description: Predicted to be involved in protein transport. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in recycling endosome membrane and trans-Golgi network membrane. Orthologous to human SCAMP2 (secretory carrier membrane protein 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI875466; Sc; Sc2; secretory carrier-associated membrane protein 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39957,468,227 - 57,496,081 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl957,468,226 - 57,496,078 (+)EnsemblGRCm39 Ensembl
GRCm38957,560,944 - 57,588,798 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl957,560,943 - 57,588,795 (+)EnsemblGRCm38mm10GRCm38
MGSCv37957,408,751 - 57,436,605 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36957,359,127 - 57,386,932 (+)NCBIMGSCv36mm8
Celera954,796,744 - 54,824,602 (+)NCBICelera
Cytogenetic Map9BNCBI
cM Map931.05NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
protein transport  (IBA,ISO,ISS)

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Novel SCAMPs lacking NPF repeats: ubiquitous and synaptic vesicle-specific forms implicate SCAMPs in multiple membrane-trafficking functions. Fernandez-Chacon R and Sudhof TC, J Neurosci 2000 Nov 1;20(21):7941-50.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:9378760   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:14610273   PMID:15489334   PMID:15782199   PMID:15935055  
PMID:16141072   PMID:16141073   PMID:21205824   PMID:21873635   PMID:30550785   PMID:38355793  


Genomics

Comparative Map Data
Scamp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39957,468,227 - 57,496,081 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl957,468,226 - 57,496,078 (+)EnsemblGRCm39 Ensembl
GRCm38957,560,944 - 57,588,798 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl957,560,943 - 57,588,795 (+)EnsemblGRCm38mm10GRCm38
MGSCv37957,408,751 - 57,436,605 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36957,359,127 - 57,386,932 (+)NCBIMGSCv36mm8
Celera954,796,744 - 54,824,602 (+)NCBICelera
Cytogenetic Map9BNCBI
cM Map931.05NCBI
SCAMP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381574,843,730 - 74,873,365 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1574,843,730 - 74,873,365 (-)EnsemblGRCh38hg38GRCh38
GRCh371575,136,071 - 75,165,706 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361572,924,250 - 72,952,723 (-)NCBINCBI36Build 36hg18NCBI36
Build 341572,924,249 - 72,952,723NCBI
Celera1552,087,212 - 52,115,664 (-)NCBICelera
Cytogenetic Map15q24.1NCBI
HuRef1551,934,180 - 51,962,549 (-)NCBIHuRef
CHM1_11575,255,832 - 75,284,295 (-)NCBICHM1_1
T2T-CHM13v2.01572,713,576 - 72,743,194 (-)NCBIT2T-CHM13v2.0
Scamp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8866,861,504 - 66,888,151 (+)NCBIGRCr8
mRatBN7.2857,965,612 - 57,992,248 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl857,965,631 - 57,992,646 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx863,498,434 - 63,525,054 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0861,776,011 - 61,802,631 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0859,640,557 - 59,667,178 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0862,341,584 - 62,368,215 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl862,341,613 - 62,368,214 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0862,119,177 - 62,145,787 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4861,316,260 - 61,342,886 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1861,350,069 - 61,360,762 (+)NCBI
Celera857,431,782 - 57,458,169 (+)NCBICelera
Cytogenetic Map8q24NCBI
Scamp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554503,070,683 - 3,095,168 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554503,070,944 - 3,095,168 (+)NCBIChiLan1.0ChiLan1.0
SCAMP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21664,071,512 - 64,101,474 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11568,235,182 - 68,265,158 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01553,786,314 - 53,816,203 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11573,404,173 - 73,434,025 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1573,404,173 - 73,434,025 (-)Ensemblpanpan1.1panPan2
SCAMP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13037,904,657 - 37,927,456 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3037,905,859 - 37,927,399 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3037,836,609 - 37,859,418 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03038,108,991 - 38,131,797 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3038,108,993 - 38,131,768 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13038,061,742 - 38,084,540 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03038,108,099 - 38,130,924 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03038,343,600 - 38,366,428 (-)NCBIUU_Cfam_GSD_1.0
Scamp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640115,967,188 - 115,990,511 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647133,815,203 - 33,838,628 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647133,815,251 - 33,838,565 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCAMP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl758,672,664 - 58,699,142 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1758,672,638 - 58,699,145 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2763,361,062 - 63,387,736 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SCAMP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1268,592,240 - 8,627,897 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl268,592,266 - 8,628,081 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048133,003,542 - 133,049,899 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Scamp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462489461,417 - 84,754 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462489460,276 - 84,776 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Scamp2
1000 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:504
Count of miRNA genes:344
Interacting mature miRNAs:379
Transcripts:ENSMUST00000045791
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300563Pgia5_mproteoglycan induced arthritis 5 (mouse)Not determined94883105682831177Mouse
10043867Mtbcq9_mmultiple trait body composition QTL 9 (mouse)Not determined92679642160796552Mouse
1301782Chol11_mcholesterol 11 (mouse)Not determined92929292963293072Mouse
4141754Fecq4_mfecundity QTL 4 (mouse)Not determined94754302457805204Mouse
11532712Sluc39d_msusceptibility to lung cancer 39d (mouse)92558748559587581Mouse
1301972Cocrb8_mcocaine related behavior 8 (mouse)Not determined93503447869034599Mouse
12790986Pcho9_mplasma cholesterol 9 (mouse)93809957572099575Mouse
10043987Stheal13_msoft tissue heal 13 (mouse)Not determined92679642160796552Mouse
12790990Tgl7_mtriglyceride 7 (mouse)95455996088559960Mouse
1558872Ibdq1_minflammatory bowel disease QTL 1 (mouse)Not determined93397884073439255Mouse
14746993Manh66_mmandible shape 66 (mouse)94981404883814048Mouse
12790992Arlsq1_maortic root lesion size QTL 1 (mouse)93809957572099575Mouse
12738449Spcq2_msperm count QTL 2 (mouse)93939988573399885Mouse
1301184Bdln4_mbody length 4 (mouse)Not determined95015132084151448Mouse
1301702Brm1_mbrachyury modifier 1 (mouse)Not determined94080504774805204Mouse
1300932Hdlq17_mHDL QTL 17 (mouse)Not determined92679642160796552Mouse
1301252Etohc3_methanol consumption 3 (mouse)Not determined93503447869034599Mouse
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49452421101406120Mouse
1357709Si5lq3_mserum IGFBP-5 level QTL 3 (mouse)Not determined93311102567111140Mouse
12791002Arlsq2_maortic root lesion size QTL 2 (mouse)93809957572099575Mouse
10043971Obq32_mobesity QTL 32 (mouse)Not determined93781952871819528Mouse
10043847Hdlq89_mHDL QTL 89 (mouse)Not determined92929292963293072Mouse
10045639Heal28_mwound healing/regeneration 28 (mouse)Not determined94348071477480860Mouse
13525008Hrtiq1_mheart rate time index, QTL 1 (mouse)95242609868556008Mouse
4141148Cq5_mcholesterol QTL 5 (mouse)Not determined93245242166452546Mouse
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93730619798701707Mouse
1301558Stheal8_msoft tissue heal 8 (mouse)Not determined94348071477480860Mouse
1301365Ap5q_malcohol preference 5 QTL (mouse)Not determined93005316464053277Mouse
1357746Vtbt7_mvertebral trabecular bone trait 7 (mouse)Not determined93073991564740021Mouse
1301435Trigq1_mtriglyceride QTL 1 (mouse)Not determined94442817478428262Mouse
1301051Eae9_msusceptibility to experimental allergic encephalomyelitis 9 (mouse)Not determined94942029863239852Mouse
1301049El4_mepilepsy 4 (mouse)Not determined94942029867151448Mouse
1301241Renf1_mrenal failure 1 (mouse)Not determined95203447899792481Mouse
1301692Hts_mhypothermia sensitivity (mouse)Not determined93251117266511421Mouse
1558968Tbdr1_mbody temperature response to dietary restriction, QTL 1 (mouse)Not determined93503447869034599Mouse
4141071Ath29_matherosclerosis 29 (mouse)Not determined94041959474607925Mouse
4141323Ptnu3_mproteinuria 3 (mouse)Not determined93288970266889836Mouse
11532696Sluc39c_msusceptibility to lung cancer 39c (mouse)92558748559587581Mouse
1302180Actd4_mactivity-distance traveled 4 (mouse)Not determined93243456366434857Mouse
11532695Sluc39b_msusceptibility to lung cancer 39b (mouse)92558748559587581Mouse
11532694Sluc39a_msusceptibility to lung cancer 39a (mouse)92558748559587581Mouse
13208563Bmiq8_mbody mass index QTL 8 (mouse)92491129668907282Mouse
4141572Ntta3_mneurotensin transcript abundance 3 (mouse)Not determined4659767165831177Mouse
10043877Adip21_madiposity 21 (mouse)Not determined95643910890439255Mouse
10043878Adip20_madiposity 20 (mouse)Not determined92725119461251323Mouse
1300716Cd4ts4_mCD4 T cell subset 4 (mouse)Not determined94883105682831177Mouse

Markers in Region
AI875466  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38957,588,396 - 57,588,484UniSTSGRCm38
MGSCv37957,436,203 - 57,436,291UniSTSGRCm37
Celera954,824,200 - 54,824,288UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map9BUniSTS
Whitehead/MRC_RH9572.09UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000045791   ⟹   ENSMUSP00000038350
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl957,468,226 - 57,496,078 (+)Ensembl
GRCm38.p6 Ensembl957,560,943 - 57,588,795 (+)Ensembl
Ensembl Acc Id: ENSMUST00000213662
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl957,468,257 - 57,485,275 (+)Ensembl
GRCm38.p6 Ensembl957,560,974 - 57,577,992 (+)Ensembl
Ensembl Acc Id: ENSMUST00000215942   ⟹   ENSMUSP00000148996
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl957,470,190 - 57,484,980 (+)Ensembl
GRCm38.p6 Ensembl957,562,907 - 57,577,697 (+)Ensembl
Ensembl Acc Id: ENSMUST00000216667
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl957,494,001 - 57,495,015 (+)Ensembl
GRCm38.p6 Ensembl957,586,718 - 57,587,732 (+)Ensembl
Ensembl Acc Id: ENSMUST00000216986   ⟹   ENSMUSP00000150920
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl957,468,241 - 57,488,195 (+)Ensembl
GRCm38.p6 Ensembl957,560,958 - 57,580,912 (+)Ensembl
Ensembl Acc Id: ENSMUST00000217200
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl957,489,133 - 57,494,725 (+)Ensembl
GRCm38.p6 Ensembl957,581,850 - 57,587,442 (+)Ensembl
RefSeq Acc Id: NM_001378928   ⟹   NP_001365857
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39957,468,227 - 57,496,081 (+)NCBI
GRCm38957,560,944 - 57,588,798 (+)NCBI
Sequence:
RefSeq Acc Id: NM_022813   ⟹   NP_073724
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39957,468,227 - 57,496,081 (+)NCBI
GRCm38957,560,944 - 57,588,798 (+)NCBI
MGSCv37957,408,751 - 57,436,605 (+)RGD
Celera954,796,744 - 54,824,602 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_073724   ⟸   NM_022813
- Peptide Label: isoform 2
- UniProtKB: Q9ERN0 (UniProtKB/Swiss-Prot),   Q3TAL2 (UniProtKB/TrEMBL),   Q3TU28 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001365857   ⟸   NM_001378928
- Peptide Label: isoform 1
- UniProtKB: Q3TU28 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000150920   ⟸   ENSMUST00000216986
Ensembl Acc Id: ENSMUSP00000038350   ⟸   ENSMUST00000045791
Ensembl Acc Id: ENSMUSP00000148996   ⟸   ENSMUST00000215942

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ERN0-F1-model_v2 AlphaFold Q9ERN0 1-329 view protein structure

Promoters
RGD ID:6845118
Promoter ID:MM_KWN:57543
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_022813
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36957,408,606 - 57,409,106 (+)MPROMDB
RGD ID:8669746
Promoter ID:EPDNEW_M12903
Type:initiation region
Name:Scamp2_1
Description:Mus musculus secretory carrier membrane protein 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38957,560,945 - 57,561,005EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1346518 AgrOrtholog
Ensembl Genes ENSMUSG00000040188 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000045791 ENTREZGENE
  ENSMUST00000045791.11 UniProtKB/Swiss-Prot
  ENSMUST00000215942.2 UniProtKB/TrEMBL
  ENSMUST00000216986.2 UniProtKB/TrEMBL
InterPro SCAMP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:24044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1346518 ENTREZGENE
NCBI Gene 24044 ENTREZGENE
PANTHER PTHR10687 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SCAMP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Scamp2 PhenoGen
UniProt A0A1L1SQD1_MOUSE UniProtKB/TrEMBL
  A0A1L1SUU4_MOUSE UniProtKB/TrEMBL
  Q3TAL2 ENTREZGENE, UniProtKB/TrEMBL
  Q3TU28 ENTREZGENE, UniProtKB/TrEMBL
  Q9ERN0 ENTREZGENE, UniProtKB/Swiss-Prot