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Gene: AKR1A1 (aldo-keto reductase family 1 member A1) Homo sapiens
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Symbol: AKR1A1
Name: aldo-keto reductase family 1 member A1
Description: Exhibits L-glucuronate reductase activity and glucuronolactone reductase activity. Involved in daunorubicin metabolic process and doxorubicin metabolic process. Localizes to the extracellular exosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alcohol dehydrogenase; alcohol dehydrogenase [NADP(+)]; alcohol dehydrogenase [NADP+]; aldehyde reductase; aldo-keto reductase family 1, member A1 (aldehyde reductase); ALDR1; ALR; ARM; DD3; dihydrodiol dehydrogenase 3; epididymis secretory protein Li 6; epididymis secretory sperm binding protein Li 165mP; glucuronate reductase; glucuronolactone reductase; HEL-S-165mP; HEL-S-6; MGC12529; MGC1380
Orthologs:
Mus musculus (house mouse) : Akr1a1 (aldo-keto reductase family 1, member A1 (aldehyde reductase))  MGI  Alliance
Rattus norvegicus (Norway rat) : Akr1a1 (aldo-keto reductase family 1 member A1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Akr1a1 (aldo-keto reductase family 1 member A1)
Pan paniscus (bonobo/pygmy chimpanzee) : AKR1A1 (aldo-keto reductase family 1 member A1)
Canis lupus familiaris (dog) : AKR1A1 (aldo-keto reductase family 1 member A1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Akr1a1 (aldo-keto reductase family 1 member A1)
Sus scrofa (pig) : AKR1A1 (aldo-keto reductase family 1 member A1)
Chlorocebus sabaeus (green monkey) : AKR1A1 (aldo-keto reductase family 1 member A1)
Heterocephalus glaber (naked mole-rat) : Akr1a1 (aldo-keto reductase family 1 member A1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl145,550,543 - 45,570,049 (+)Ensembl
GRCh38145,550,779 - 45,570,051 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37146,016,455 - 46,035,723 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36145,789,085 - 45,808,308 (+)NCBINCBI36hg18NCBI36
Build 34145,685,590 - 45,704,813NCBI
Celera144,300,464 - 44,319,706 (+)NCBI
Cytogenetic Map1p34.1NCBI
HuRef144,127,818 - 44,147,063 (+)NCBIHuRef
CHM1_1146,133,579 - 46,152,870 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on AKR1A1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68486
Created: 2001-07-11
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.