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Gene: Pde1c (phosphodiesterase 1C) Mus musculus
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Symbol: Pde1c
Name: phosphodiesterase 1C
Description: Predicted to have cAMP binding activity; calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity; and calmodulin-dependent cyclic-nucleotide phosphodiesterase activity. Involved in sensory perception of smell. Localizes to cilium. Is expressed in several structures, including alimentary system; integumental system; male reproductive gland or organ; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness. Orthologous to human PDE1C (phosphodiesterase 1C); PARTICIPATES IN protein kinase A (PKA) signaling pathway; purine metabolic pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3',5'-cyclic-AMP phosphodiesterase; 3',5'-cyclic-GMP phosphodiesterase; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; cam-PDE 1C
Orthologs:
Homo sapiens (human) : PDE1C (phosphodiesterase 1C)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pde1c (phosphodiesterase 1C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde1c (phosphodiesterase 1C)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE1C (phosphodiesterase 1C)
Canis lupus familiaris (dog) : PDE1C (phosphodiesterase 1C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde1c (phosphodiesterase 1C)
Sus scrofa (pig) : PDE1C (phosphodiesterase 1C)
Chlorocebus sabaeus (African green monkey) : PDE1C (phosphodiesterase 1C)
Heterocephalus glaber (naked mole-rat) : Pde1c (phosphodiesterase 1C)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl656,069,804 - 56,652,487 (-)EnsemblGRCm38mm10GRCm38
GRCm38656,069,798 - 56,652,510 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37656,019,798 - 56,319,628 (-)NCBIGRCm37mm9NCBIm37
MGSCv36656,011,359 - 56,292,097 (-)NCBImm8
Celera656,847,453 - 57,126,888 (-)NCBICelera
Celera660,236,120 - 60,238,326 (-)NCBICelera
Cytogenetic Map6B3NCBI
cM Map627.65NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pde1c
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68464
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.