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Gene: Pde1c (phosphodiesterase 1C) Mus musculus
Symbol: Pde1c
Name: phosphodiesterase 1C
Description: Predicted to have cAMP binding activity; calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity; and calmodulin-dependent cyclic-nucleotide phosphodiesterase activity. Involved in sensory perception of smell. Localizes to cilium. Is expressed in several structures, including alimentary system; integumental system; male reproductive gland or organ; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness. Orthologous to human PDE1C (phosphodiesterase 1C); PARTICIPATES IN protein kinase A (PKA) signaling pathway; purine metabolic pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3',5'-cyclic-AMP phosphodiesterase; 3',5'-cyclic-GMP phosphodiesterase; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; cam-PDE 1C
Homo sapiens (human) : PDE1C (phosphodiesterase 1C)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pde1c (phosphodiesterase 1C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde1c (phosphodiesterase 1C)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE1C (phosphodiesterase 1C)
Canis lupus familiaris (dog) : PDE1C (phosphodiesterase 1C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde1c (phosphodiesterase 1C)
Sus scrofa (pig) : PDE1C (phosphodiesterase 1C)
Chlorocebus sabaeus (African green monkey) : PDE1C (phosphodiesterase 1C)
Heterocephalus glaber (naked mole-rat) : Pde1c (phosphodiesterase 1C)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl656,069,804 - 56,652,487 (-)EnsemblGRCm38mm10GRCm38
GRCm38656,069,798 - 56,652,510 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37656,019,798 - 56,319,628 (-)NCBIGRCm37mm9NCBIm37
MGSCv36656,011,359 - 56,292,097 (-)NCBImm8
Celera656,847,453 - 57,126,888 (-)NCBICelera
Celera660,236,120 - 60,238,326 (-)NCBICelera
Cytogenetic Map6B3NCBI
cM Map627.65NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pde1c
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68464
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.