Bcam (basal cell adhesion molecule (Lutheran blood group)) - Rat Genome Database

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Gene: Bcam (basal cell adhesion molecule (Lutheran blood group)) Rattus norvegicus
Analyze
Symbol: Bcam
Name: basal cell adhesion molecule (Lutheran blood group)
RGD ID: 68378
Description: Predicted to enable laminin binding activity and laminin receptor activity. Predicted to be involved in cell-matrix adhesion. Predicted to act upstream of or within cell adhesion. Predicted to be located in cell surface. Predicted to be active in plasma membrane. Orthologous to human BCAM (basal cell adhesion molecule (Lutheran blood group)); INTERACTS WITH 1,1-dichloroethene; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: B-CAM cell surface glycoprotein; basal cell adhesion molecule; Lu; lutheran antigen; Lutheran blood group (Auberger b antigen included)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8188,542,971 - 88,557,358 (-)NCBIGRCr8
mRatBN7.2179,415,016 - 79,429,403 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl179,415,017 - 79,429,403 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx184,809,588 - 84,823,988 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0193,361,117 - 93,375,464 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0186,564,702 - 86,579,102 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0180,674,463 - 80,689,122 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,674,444 - 80,689,171 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,939,821 - 81,954,480 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4179,067,352 - 79,081,739 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1179,145,463 - 79,159,850 (-)NCBI
Celera173,873,493 - 73,887,880 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (ISO)
1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-vinylcyclohexene dioxide  (ISO)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
choline  (ISO)
cisplatin  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
dibutyl phthalate  (ISO)
diethyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
hydrogen cyanide  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
methoxychlor  (ISO)
mitoxantrone  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
ochratoxin A  (EXP)
ozone  (ISO)
paracetamol  (EXP)
pirinixic acid  (ISO)
potassium cyanide  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sulforaphane  (ISO)
sulindac sulfide  (ISO)
thapsigargin  (EXP)
titanium dioxide  (ISO)
tolcapone  (EXP)
trichloroethene  (EXP,ISO)
valproic acid  (ISO)
vancomycin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cell adhesion  (ISO,NAS)
cell-matrix adhesion  (IEA,ISO)

Cellular Component
cell surface  (IEA,ISO)
membrane  (IEA)
plasma membrane  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Characterization of the laminin binding domains of the Lutheran blood group glycoprotein. El Nemer W, etal., J Biol Chem 2001 Jun 29;276(26):23757-62.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
9. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:10630290   PMID:11507772   PMID:16236823   PMID:19056867   PMID:23376485   PMID:24223164   PMID:24453976   PMID:27068509   PMID:27559042   PMID:29476059   PMID:36252138  


Genomics

Comparative Map Data
Bcam
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8188,542,971 - 88,557,358 (-)NCBIGRCr8
mRatBN7.2179,415,016 - 79,429,403 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl179,415,017 - 79,429,403 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx184,809,588 - 84,823,988 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0193,361,117 - 93,375,464 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0186,564,702 - 86,579,102 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0180,674,463 - 80,689,122 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,674,444 - 80,689,171 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,939,821 - 81,954,480 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4179,067,352 - 79,081,739 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1179,145,463 - 79,159,850 (-)NCBI
Celera173,873,493 - 73,887,880 (-)NCBICelera
Cytogenetic Map1q21NCBI
BCAM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381944,809,059 - 44,821,421 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1944,809,071 - 44,821,421 (+)EnsemblGRCh38hg38GRCh38
GRCh371945,312,316 - 45,324,678 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361950,004,178 - 50,016,518 (+)NCBINCBI36Build 36hg18NCBI36
Build 341950,004,216 - 50,016,511NCBI
Celera1942,115,754 - 42,128,094 (+)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1941,743,446 - 41,755,786 (+)NCBIHuRef
CHM1_11945,315,022 - 45,327,384 (+)NCBICHM1_1
T2T-CHM13v2.01947,633,808 - 47,646,153 (+)NCBIT2T-CHM13v2.0
Bcam
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39719,490,063 - 19,504,457 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl719,490,056 - 19,504,941 (-)EnsemblGRCm39 Ensembl
GRCm38719,756,138 - 19,770,532 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,756,131 - 19,771,016 (-)EnsemblGRCm38mm10GRCm38
MGSCv37720,341,487 - 20,355,881 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36718,914,661 - 18,928,997 (-)NCBIMGSCv36mm8
Celera717,162,318 - 17,178,338 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.94NCBI
Bcam
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555551,942,583 - 1,950,372 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555551,943,445 - 1,950,810 (+)NCBIChiLan1.0ChiLan1.0
BCAM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22050,968,108 - 50,980,749 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11952,840,067 - 52,852,703 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01941,756,492 - 41,769,132 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11950,361,780 - 50,374,600 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1950,361,780 - 50,374,600 (+)Ensemblpanpan1.1panPan2
BCAM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11110,575,883 - 110,585,100 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1110,575,924 - 110,585,035 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1110,056,830 - 110,066,172 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01111,138,698 - 111,148,041 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1111,137,660 - 111,148,040 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11110,780,182 - 110,789,389 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01110,415,767 - 110,425,111 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01111,285,027 - 111,294,370 (-)NCBIUU_Cfam_GSD_1.0
Bcam
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,109,872 - 17,118,596 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367061,457,174 - 1,467,848 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367061,451,609 - 1,465,939 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BCAM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl651,298,806 - 51,310,528 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1651,298,743 - 51,310,543 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,198,260 - 47,210,371 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BCAM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1638,288,507 - 38,301,587 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl638,288,537 - 38,301,634 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607317,855,578 - 17,868,876 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bcam
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249071,695,698 - 1,708,345 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249071,696,078 - 1,705,260 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Bcam
91 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:109
Count of miRNA genes:77
Interacting mature miRNAs:92
Transcripts:ENSRNOT00000045574
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15389511782174945Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)17219768090508767Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14936146582174945Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13483685879836858Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)15034351099980958Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)15389511782174945Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)17843075491209302Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000045574   ⟹   ENSRNOP00000047809
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl179,415,017 - 79,429,403 (-)Ensembl
Rnor_6.0 Ensembl180,674,444 - 80,689,171 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098572   ⟹   ENSRNOP00000089177
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl179,415,547 - 79,427,687 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102437   ⟹   ENSRNOP00000085184
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl179,415,017 - 79,427,860 (-)Ensembl
RefSeq Acc Id: NM_031752   ⟹   NP_113940
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,542,971 - 88,557,358 (-)NCBI
mRatBN7.2179,415,016 - 79,429,403 (-)NCBI
Rnor_6.0180,674,463 - 80,689,122 (-)NCBI
Rnor_5.0181,939,821 - 81,954,480 (-)NCBI
RGSC_v3.4179,067,352 - 79,081,739 (-)RGD
Celera173,873,493 - 73,887,880 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_113940 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH72479 (Get FASTA)   NCBI Sequence Viewer  
  BAB16052 (Get FASTA)   NCBI Sequence Viewer  
  EDM08137 (Get FASTA)   NCBI Sequence Viewer  
  EDM08138 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000047809.3
  ENSRNOP00000085184.1
  ENSRNOP00000089177.1
GenBank Protein Q9ESS6 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_113940   ⟸   NM_031752
- Peptide Label: precursor
- UniProtKB: Q9ESS6 (UniProtKB/Swiss-Prot),   A0A8I6A1Q0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000047809   ⟸   ENSRNOT00000045574
Ensembl Acc Id: ENSRNOP00000089177   ⟸   ENSRNOT00000098572
Ensembl Acc Id: ENSRNOP00000085184   ⟸   ENSRNOT00000102437
Protein Domains
Ig-like   Ig-like C2-type   Ig-like V-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ESS6-F1-model_v2 AlphaFold Q9ESS6 1-624 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689782
Promoter ID:EPDNEW_R307
Type:multiple initiation site
Name:Bcam_1
Description:basal cell adhesion molecule
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0180,689,138 - 80,689,198EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:68378 AgrOrtholog
BioCyc Gene G2FUF-60485 BioCyc
Ensembl Genes ENSRNOG00000029399 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000045574.5 UniProtKB/Swiss-Prot
  ENSRNOT00000098572.1 UniProtKB/TrEMBL
  ENSRNOT00000102437.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7104047 IMAGE-MGC_LOAD
InterPro CD80_C2-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Surface_Rcpt/Adhesion_Mol UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:78958 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91621 IMAGE-MGC_LOAD
NCBI Gene 78958 ENTREZGENE
PANTHER BASAL CELL ADHESION MOLECULE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CELL SURFACE GLYCOPROTEIN MUC18-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C2-set_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Bcam PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000029399 RatGTEx
SMART IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC229277
UniProt A0A8I6A1Q0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AB76_RAT UniProtKB/TrEMBL
  A6J8U6_RAT UniProtKB/TrEMBL
  BCAM_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-14 Bcam  basal cell adhesion molecule (Lutheran blood group)  Bcam  basal cell adhesion molecule  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Bcam  basal cell adhesion molecule  Lu  Lutheran blood group (Auberger b antigen included)  Symbol and Name updated 1299863 APPROVED
2002-06-10 Lu  Lutheran blood group (Auberger b antigen included)      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_product member of the Ig superfamily 724415