LOC100909593 (class II histocompatibility antigen, M alpha chain-like) - Rat Genome Database

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Gene: LOC100909593 (class II histocompatibility antigen, M alpha chain-like) Rattus norvegicus
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Symbol: LOC100909593
Name: class II histocompatibility antigen, M alpha chain-like
RGD ID: 6502526
Description: Predicted to be involved in positive regulation of germinal center formation and positive regulation of humoral immune response. Predicted to act upstream of or within several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II; chaperone cofactor-dependent protein refolding; and positive thymic T cell selection. Predicted to be located in endosome membrane; lysosomal membrane; and multivesicular body. Orthologous to human HLA-DMA (major histocompatibility complex, class II, DM alpha); INTERACTS WITH 1,2-dimethylhydrazine (ortholog); 17alpha-ethynylestradiol (ortholog); 2,2',4,4',5,5'-hexachlorobiphenyl (ortholog).
Type: protein-coding
RefSeq Status: WITHDRAWN
RGD Orthologs
Mouse
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0203,935,501 - 3,938,915 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0206,015,055 - 6,018,463 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Cytogenetic Map20 NCBI


References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7584146   PMID:7985028   PMID:8598040   PMID:8598041   PMID:8638109   PMID:8890155   PMID:9432982   PMID:9492004   PMID:11027433   PMID:11148202   PMID:11714799   PMID:11854359  
PMID:21795542  


Genomics

Comparative Map Data
LOC100909593
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0203,935,501 - 3,938,915 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0206,015,055 - 6,018,463 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Cytogenetic Map20 NCBI
H2-DMa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,338,667 - 34,358,075 (+)NCBIGRCm39mm39
GRCm39 Ensembl1734,338,515 - 34,358,075 (+)Ensembl
GRCm381734,119,693 - 34,139,101 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,119,541 - 34,139,101 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,272,616 - 34,275,480 (+)NCBIGRCm37mm9NCBIm37
MGSCv361733,746,082 - 33,749,555 (+)NCBImm8
Celera1736,887,536 - 36,890,397 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI

Position Markers
D20Yum76  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2204,709,029 - 4,709,134 (-)MAPPERmRatBN7.2
mRatBN7.2204,709,029 - 4,709,134 (+)MAPPERmRatBN7.2
Rnor_6.0203,936,810 - 3,936,914NCBIRnor6.0
Rnor_6.0205,242,976 - 5,243,080NCBIRnor6.0
Rnor_5.0207,304,037 - 7,304,141UniSTSRnor5.0
Rnor_5.0206,016,358 - 6,016,462UniSTSRnor5.0
RGSC_v3.4204,845,459 - 4,845,563UniSTSRGSC3.4
Celera206,309,689 - 6,309,793UniSTS
Cytogenetic Map20p12UniSTS
RH136915  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2204,707,045 - 4,707,261 (-)MAPPERmRatBN7.2
mRatBN7.2204,707,045 - 4,707,261 (+)MAPPERmRatBN7.2
Rnor_6.0205,240,993 - 5,241,208NCBIRnor6.0
Rnor_6.0203,938,682 - 3,938,897NCBIRnor6.0
Rnor_5.0206,018,230 - 6,018,445UniSTSRnor5.0
Rnor_5.0207,302,054 - 7,302,269UniSTSRnor5.0
RGSC_v3.4204,843,476 - 4,843,691UniSTSRGSC3.4
Celera206,307,706 - 6,307,921UniSTS
RH 3.4 Map2069.2UniSTS
Cytogenetic Map20p12UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_006256035   ⟹   XP_006256097
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0203,935,501 - 3,938,915 (+)NCBI
Rnor_5.0206,015,055 - 6,018,463 (+)NCBI
Protein Sequences
Protein RefSeqs XP_006256097 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_006256097   ⟸   XM_006256035


Additional Information

Database Acc Id Source(s)
NCBI Gene LOC100909593 ENTREZGENE
PhenoGen LOC100909593 PhenoGen


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-07-05 LOC100909593  class II histocompatibility antigen, M alpha chain-like      Symbol and Name status set to provisional 70820 PROVISIONAL