Tma7b (translation machinery associated 7B) - Rat Genome Database

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Gene: Tma7b (translation machinery associated 7B) Rattus norvegicus
Analyze
Symbol: Tma7b
Name: translation machinery associated 7B
RGD ID: 6497475
Description: Orthologous to human TMA7 (translation machinery associated 7 homolog) and TMA7B (translation machinery associated 7 homolog B).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: coiled-coil domain-containing protein 72-like; hypothetical protein LOC685117; LOC100910678; LOC685117; translation machinery-associated protein 7-like
RGD Orthologs
Human
Mouse
Bonobo
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8479,661,519 - 79,662,021 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.2478,330,663 - 78,331,163 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl478,330,318 - 78,331,144 (-)EnsemblmRatBN7.2
Rnor_6.0479,015,083 - 79,015,705 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl479,015,316 - 79,015,660 (-)Ensemblrn6Rnor6.0
Rnor_5.04143,704,076 - 143,704,698 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4477,478,620 - 77,479,256 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera473,265,349 - 73,265,823 (-)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse:




References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Tma7b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8479,661,519 - 79,662,021 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.2478,330,663 - 78,331,163 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl478,330,318 - 78,331,144 (-)EnsemblmRatBN7.2
Rnor_6.0479,015,083 - 79,015,705 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl479,015,316 - 79,015,660 (-)Ensemblrn6Rnor6.0
Rnor_5.04143,704,076 - 143,704,698 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4477,478,620 - 77,479,256 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera473,265,349 - 73,265,823 (-)NCBICelera
Cytogenetic Map4q24NCBI
TMA7B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382239,960,397 - 39,964,905 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2239,960,397 - 39,964,905 (+)Ensemblhg38GRCh38
GRCh38.p14 Ensembl2239,960,397 - 39,964,718 (+)NCBIhg38GRCh38
GRCh372240,356,401 - 40,360,909 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map22q13.1NCBI
T2T-CHM13v2.02240,431,389 - 40,435,898 (+)NCBIT2T-CHM13v2.0
Gm15610
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3959,021,916 - 9,022,396 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl59,021,948 - 9,022,142 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3858,971,916 - 8,972,396 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl58,971,948 - 8,972,142 (+)Ensemblmm10GRCm38
Celera58,891,325 - 8,891,805 (+)NCBICelera
Cytogenetic Map5A1NCBI
cM Map53.51NCBI
TMA7B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22349,810,114 - 49,811,822 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12252,501,396 - 52,503,122 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02220,869,045 - 20,869,829 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12238,689,511 - 38,689,960 (+)NCBIPanPan1.1PanPan1.1panPan2

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:20
Count of miRNA genes:19
Interacting mature miRNAs:19
Transcripts:ENSRNOT00000068441
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)439431983123203361Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)459753119104753119Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44140057786400577Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44442502489425024Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)474233320119233320Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)458817672103817672Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)474233320119233320Rat
61336Bp21Blood pressure QTL 214.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45808014680212111Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)471647492116647492Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)427862204126119996Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44140060386400603Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)475939858140508796Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)43044896182336920Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)465060960127749483Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)451085655113588029Rat
2317588Eae27Experimental allergic encephalomyelitis QTL 27nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)469036742114036742Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)440490442117737312Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)457613339151163960Rat
4889969Bss96Bone structure and strength QTL 964.9tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)457613242102613242Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
4889972Bss97Bone structure and strength QTL 975.6tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)457613242102613242Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
5685012Bmd87Bone mineral density QTL 875.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)43511329080113290Rat
5685009Bmd86Bone mineral density QTL 863.7tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)457613242102613242Rat
634311Sach7Saccharin preference QTL 7taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)45807987582597589Rat
2306547Iddm38Insulin dependent diabetes mellitus QTL 38blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)468353567113353567Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
2306545Iddm39Insulin dependent diabetes mellitus QTL 39blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)478687630123687630Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41170660492690519Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)474169813134199155Rat
2312569Pur19Proteinuria QTL 193.40.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)459836842104836842Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)43726957782269577Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)475939858140508796Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)46104105794638356Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463245026129846354Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)464209744109209744Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)44140057786400577Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)457664252127749483Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45807987592690793Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463224393108224393Rat
7394826Bw126Body weight QTL 1260.002body mass (VT:0001259)body weight gain (CMO:0000420)46390045888813920Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)433538597116185060Rat
631671Iddm11Insulin dependent diabetes mellitus QTL 113.60.0012blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)45960331980216952Rat

Markers in Region
PMC152658P4  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2478,330,587 - 78,330,999 (+)MAPPERmRatBN7.2
mRatBN7.2478,330,587 - 78,331,102 (+)MAPPERmRatBN7.2
Rnor_6.0479,014,983 - 79,015,393NCBIRnor6.0
Rnor_6.0479,014,983 - 79,015,543NCBIRnor6.0
Rnor_5.04143,703,993 - 143,704,553UniSTSRnor5.0
Rnor_5.04143,703,993 - 143,704,403UniSTSRnor5.0
RGSC_v3.4477,478,695 - 77,479,105UniSTSRGSC3.4
Celera473,265,249 - 73,265,659UniSTS
RH140669  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
14 5 57 152 68 61 46 70 46 6 289 154 11 136 73 83 15 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000068441   ⟹   ENSRNOP00000060729
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl479,015,316 - 79,015,660 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106523   ⟹   ENSRNOP00000088351
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl478,330,318 - 78,331,144 (-)Ensembl
RefSeq Acc Id: XM_039108671   ⟹   XP_038964599
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8479,661,519 - 79,662,021 (-)NCBI
mRatBN7.2478,330,663 - 78,331,163 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038964599 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000088351.1
  ENSRNOP00000109434
Ensembl Acc Id: ENSRNOP00000060729   ⟸   ENSRNOT00000068441
RefSeq Acc Id: XP_038964599   ⟸   XM_039108671
- UniProtKB: A0A8I6A4Y0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000088351   ⟸   ENSRNOT00000106523

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZP49-F1-model_v2 AlphaFold D3ZP49 1-64 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693039
Promoter ID:EPDNEW_R3563
Type:multiple initiation site
Name:LOC100910678_1
Description:coiled-coil domain-containing protein 72-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0479,015,685 - 79,015,745EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:6497475 AgrOrtholog
BioCyc Gene G2FUF-44916 BioCyc
Ensembl Genes ENSRNOG00000043400 Ensembl
  ENSRNOG00000070474 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000086479 ENTREZGENE
Ensembl Transcript ENSRNOT00000106523.1 UniProtKB/TrEMBL
  ENSRNOT00000173144 ENTREZGENE
InterPro TMA7 UniProtKB/TrEMBL
NCBI Gene LOC100910678 ENTREZGENE
PANTHER PTHR28632 UniProtKB/TrEMBL
Pfam TMA7 UniProtKB/TrEMBL
PhenoGen Tma7b PhenoGen
RatGTEx ENSRNOG00000043400 RatGTEx
  ENSRNOG00000070474 RatGTEx
  ENSRNOG00000086479 RatGTEx
UniProt A0A8I6A4Y0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-23 Tma7b  translation machinery associated 7B  LOC100910678  coiled-coil domain-containing protein 72-like  Name and Symbol changed 629549 APPROVED
2015-07-29 LOC100910678  coiled-coil domain-containing protein 72-like  LOC685117  hypothetical protein LOC685117  Data merged from RGD:1597765 737654 PROVISIONAL
2012-07-05 LOC100910678  coiled-coil domain-containing protein 72-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-01-09 LOC685117  hypothetical protein LOC685117  LOC679388  hypothetical protein LOC679388  Data merged from RGD:1589487 1643240 APPROVED
2006-11-20 LOC685117  hypothetical protein LOC685117      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC679388  hypothetical protein LOC679388      Symbol and Name status set to provisional 70820 PROVISIONAL