Gene: LOC100911248 (crk-like protein-like) Rattus norvegicus
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Symbol: LOC100911248
Name: crk-like protein-like
Description: INVOLVED IN acetylcholine receptor signaling pathway (inferred); activation of GTPase activity (inferred); activation of MAPK activity (inferred); FOUND IN extrinsic component of postsynaptic membrane (inferred); neuromuscular junction (inferred); protein-containing complex (inferred)
AGR Description: Predicted to be involved in several processes, including animal organ development, cell surface receptor signaling pathway, and nervous system development; predicted to localize to the extrinsic component of postsynaptic membrane, neuromuscular junction, and protein-containing complex; orthologous to human CRKL (CRK like proto-oncogene, adaptor protein).
Merged Description: Predicted to be involved in several processes, including animal organ development, cell surface receptor signaling pathway, and nervous system development; predicted to localize to the extrinsic component of postsynaptic membrane, neuromuscular junction, and protein-containing complex; orthologous to human CRKL (CRK like proto-oncogene, adaptor protein).
Type: protein-coding
RefSeq Status: MODEL
Orthologs:
No known orthologs. homologs ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Note: LOC100911248 appears to be a duplicate placement of Crkl (GeneID: 287942) on Rnor_6.0 that is not present on Rn_Celera (Annotation Release 105) and not supported by synteny in mouse and human. Gene neighbor LOC103693605 also appears to be a duplicate placement of Car15. BLASTing LOC100911248 XM_003751095.3 and Crkl NM_001008284.1 against the rat genome shows best hits to NC_005110.4 on Rnor_6.0 at locations where LOC100911248 and Crkl are annotated and to AC_000079.1 on Rn_Celera only at location where Crkl is annotated (Annotation Release 105). 2-seqence BLAST of Crkl NM_001008284.1 against LOC100911248 XM_003751095.3 shows high sequence identity (98% coverage, 99% identity). 2-sequence BLAST of LOC100911248 underlying component AC111344.6 against Rufy2 underlying component AABR07034750.1 shows 99% identity across a stretch of ~26 kb. [25 Mar 2015]
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01187,778,338 - 87,815,049 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01190,830,747 - 90,867,451 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations
References - curated
RGD Disease Portals

Genomics

Position Markers
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on LOC100911248
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 6493647
Created: 2012-07-05
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.