Znf709l (zinc finger protein 709 like) - Rat Genome Database

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Gene: Znf709l (zinc finger protein 709 like) Rattus norvegicus
Analyze
Symbol: Znf709l (Ensembl: LOC100911320)
Name: zinc finger protein 709 like (Ensembl:zinc finger protein 709-like)
RGD ID: 6493372
Description: Predicted to be involved in regulation of DNA-templated transcription. Orthologous to human ZNF709 (zinc finger protein 709); INTERACTS WITH bisphenol A; paracetamol; 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100911320; zinc finger protein 317; zinc finger protein 627; zinc finger protein 709; zinc finger protein 709-like
RGD Orthologs
Human
Mouse
Bonobo
Dog
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8828,986,472 - 28,997,594 (+)NCBIGRCr8
mRatBN7.2820,710,114 - 20,721,236 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl820,710,461 - 20,720,246 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0823,176,910 - 23,197,896 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl823,193,181 - 23,197,319 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0823,241,604 - 23,250,639 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera822,084,825 - 22,108,090 (+)NCBICelera
Cytogenetic Map8q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Znf709l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8828,986,472 - 28,997,594 (+)NCBIGRCr8
mRatBN7.2820,710,114 - 20,721,236 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl820,710,461 - 20,720,246 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0823,176,910 - 23,197,896 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl823,193,181 - 23,197,319 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0823,241,604 - 23,250,639 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera822,084,825 - 22,108,090 (+)NCBICelera
Cytogenetic Map8q13NCBI
ZNF709
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381912,461,184 - 12,484,816 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1912,461,184 - 12,513,854 (-)EnsemblGRCh38hg38GRCh38
GRCh371912,571,998 - 12,595,630 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361912,435,743 - 12,456,632 (-)NCBINCBI36Build 36hg18NCBI36
Celera1912,465,820 - 12,489,452 (-)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef1912,145,183 - 12,168,524 (-)NCBIHuRef
CHM1_11912,571,913 - 12,595,533 (-)NCBICHM1_1
T2T-CHM13v2.01912,589,588 - 12,613,220 (-)NCBIT2T-CHM13v2.0
Zfp872
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39922,099,462 - 22,113,419 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl922,099,386 - 22,113,419 (+)EnsemblGRCm39 Ensembl
GRCm38922,188,166 - 22,202,123 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl922,188,090 - 22,202,123 (+)EnsemblGRCm38mm10GRCm38
MGSCv37921,992,610 - 22,006,567 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36921,938,568 - 21,952,525 (+)NCBIMGSCv36mm8
Celera919,457,987 - 19,472,477 (+)NCBICelera
Cytogenetic Map9A3NCBI
cM Map98.57NCBI
ZNF709
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22017,393,562 - 17,443,377 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11916,395,134 - 16,444,003 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01912,026,842 - 12,076,648 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11912,776,817 - 12,797,325 (-)NCBIpanpan1.1PanPan1.1panPan2
LOC100682654
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12049,614,418 - 49,647,119 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2049,437,519 - 49,521,050 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02050,083,055 - 50,166,581 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12049,294,219 - 49,377,572 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02049,721,762 - 49,804,784 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02049,963,112 - 50,046,278 (+)NCBIUU_Cfam_GSD_1.0
ZNF709
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1611,196,988 - 11,213,575 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660748,589,747 - 8,609,072 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Znf709l
69 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:24
Count of miRNA genes:21
Interacting mature miRNAs:24
Transcripts:ENSRNOT00000071703
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590084Insglur5Insulin/glucose ratio QTL 518.540.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)8124597739Rat
2317882Alcrsp24Alcohol response QTL 243.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)8125902202Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)8209764047097640Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)8209764047097640Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)8209764047097640Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)8209764047097640Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)8470581049705810Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)8470581049705810Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)8470581049705810Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8767057852670578Rat
1354595Despr4Despair related QTL 42.160.0036locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)8768895552688955Rat
1354627Despr14Despair related QTL 140.0056locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8768895552688955Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)8873663553736635Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)8873663553736635Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)8971222053356647Rat
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1558646Swd5Spike wave discharge measurement QTL 53.450.00036brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)81490675159906751Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)81629044461290444Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat

Markers in Region
BF416098  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2820,701,595 - 20,701,788 (+)MAPPERmRatBN7.2
Rnor_6.0823,180,010 - 23,180,202NCBIRnor6.0
Rnor_5.0823,233,281 - 23,233,473UniSTSRnor5.0
Celera822,090,280 - 22,090,472UniSTS
RH 3.4 Map8181.9UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 41 9
Low 3 42 57 41 19 41 8 11 33 35 32 11 8
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000071703   ⟹   ENSRNOP00000066435
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl823,193,181 - 23,197,319 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000099542   ⟹   ENSRNOP00000093584
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl820,710,461 - 20,720,246 (+)Ensembl
RefSeq Acc Id: NM_001409238   ⟹   NP_001396167
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8828,986,472 - 28,996,261 (+)NCBI
mRatBN7.2820,710,460 - 20,720,250 (+)NCBI
RefSeq Acc Id: XM_039082259   ⟹   XP_038938187
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8828,986,593 - 28,997,594 (+)NCBI
mRatBN7.2820,710,581 - 20,721,236 (+)NCBI
RefSeq Acc Id: XM_063264719   ⟹   XP_063120789
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8828,991,838 - 28,997,594 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001396167 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938187 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120789 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL78221 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000093584
  ENSRNOP00000093584.1
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000066435   ⟸   ENSRNOT00000071703
RefSeq Acc Id: XP_038938187   ⟸   XM_039082259
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000093584   ⟸   ENSRNOT00000099542
RefSeq Acc Id: NP_001396167   ⟸   NM_001409238
- UniProtKB: A0A8I6AJ71 (UniProtKB/TrEMBL),   A6JNZ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120789   ⟸   XM_063264719
- Peptide Label: isoform X2
Protein Domains
C2H2-type   KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0RA93-F1-model_v2 AlphaFold M0RA93 1-465 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:6493372 AgrOrtholog
BioCyc Gene G2FUF-31383 BioCyc
Ensembl Genes ENSRNOG00000050600 Ensembl
  ENSRNOG00000069976 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000099542 ENTREZGENE
  ENSRNOT00000099542.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro KRAB UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene LOC100911320 ENTREZGENE
PANTHER RCG31665-RELATED UniProtKB/TrEMBL
  ZINC FINGER AND SCAN DOMAIN-CONTAINING UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PhenoGen Znf709l PhenoGen
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000050600 RatGTEx
  ENSRNOG00000069976 RatGTEx
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A8I6AJ71 ENTREZGENE, UniProtKB/TrEMBL
  A6JNZ5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-12-29 Znf709l  zinc finger protein 709 like  LOC100911320  zinc finger protein 709-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100911320  zinc finger protein 709-like      Symbol and Name status set to provisional 70820 PROVISIONAL