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Gene: LOC100911486 (multiple epidermal growth factor-like domains protein 6-like) Rattus norvegicus
Symbol: LOC100911486
Name: multiple epidermal growth factor-like domains protein 6-like
Description: Predicted to have calcium ion binding activity. Orthologous to human MEGF6 (multiple EGF like domains 6).
Type: protein-coding
RefSeq Status: MODEL
Also known as: multiple epidermal growth factor-like domains protein 6
No known orthologs. homologs ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Note: LOC100911486 appears to be a duplicate placement of Megf6 (GeneID: 65049) on Rnor_6.0 that is not present on Rn_Celera (Annotation Release 105) and not supported by synteny in mouse and human. BLASTing LOC100911486 XM_008764417.1 and Megf6 NM_022955.1 against the rat genome shows best hits to NC_005104.4 on Rnor_6.0 at locations where LOC100911486 and Megf6 are annotated and to AC_000073.1 on Rn_Celera only at location where Megf6 is annotated (Annotation Release 105). 2-sequence BLAST of Megf6 NM_022955.1 against LOC100911486 XM_008764417.1 shows high sequence identity (79% coverage, 99% identity). Although five components underlie LOC100911486, AABR07050625.1 includes the genomic region with the majority of exons that comprise XM_008764417.1. BLASTing AABR07050625.1 against the rat genome shows best hits to NC_005104.4 on Rnor_6.0 at the location where LOC100911486 is annotated (hitting itself) and the location where Megf6 is annotated. 2-sequence BLAST of AABR07050625.1 against Megf6 underlying component AABR07050628.1 shows 99% sequence identity across stretch of ~25 kb. [26 Mar 2015]
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05171,478,247 - 171,571,810 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5171,472,273 - 171,620,947 (+)Ensembl
Rnor_5.05174,953,888 - 175,048,919 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene Ontology Annotations
References - curated


QTLs in Region (Rnor_6.0)


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on LOC100911486
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 6492904
Created: 2012-07-05
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.