POU6F2-AS2 (POU6F2 antisense RNA 2) - Rat Genome Database

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Gene: POU6F2-AS2 (POU6F2 antisense RNA 2) Homo sapiens
Analyze
Symbol: POU6F2-AS2
Name: POU6F2 antisense RNA 2
RGD ID: 6480347
HGNC Page HGNC:21887
Description: INTERACTS WITH methylmercury chloride; valproic acid
Type: ncrna (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Previously known as: AC011292.2
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38738,979,895 - 39,013,567 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl738,980,370 - 39,013,551 (-)EnsemblGRCh38hg38GRCh38
GRCh37739,019,495 - 39,053,167 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map7p14.1ENTREZGENE
HuRef738,903,693 - 38,937,345 (-)NCBIHuRef
CHM1_1739,022,136 - 39,055,799 (-)NCBICHM1_1
T2T-CHM13v2.0739,136,920 - 39,170,597 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2739,057,217 - 39,090,891 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14702039   PMID:27033944   PMID:32100443   PMID:36797828  


Genomics

Variants

.
Variants in POU6F2-AS2
1 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 7p22.3-14.1(chr7:54185-41875885)x3 copy number gain See cases [RCV000051159] Chr7:54185..41875885 [GRCh38]
Chr7:54185..41915483 [GRCh37]
Chr7:149268..41882008 [NCBI36]
Chr7:7p22.3-14.1		 pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:53985-159282531)x1 copy number loss See cases [RCV000052250] Chr7:53985..159282531 [GRCh38]
Chr7:53985..159075220 [GRCh37]
Chr7:149068..158767981 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
GRCh38/hg38 7p14.3-q11.21(chr7:33328312-62377476)x3 copy number gain See cases [RCV000053532] Chr7:33328312..62377476 [GRCh38]
Chr7:33367924..61831899 [GRCh37]
Chr7:33334449..61469334 [NCBI36]
Chr7:7p14.3-q11.21		 pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:54185-159282390)x1 copy number loss See cases [RCV000135401] Chr7:54185..159282390 [GRCh38]
Chr7:54185..159075079 [GRCh37]
Chr7:149268..158767840 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
GRCh38/hg38 7p14.1-12.3(chr7:37303478-48660738)x1 copy number loss See cases [RCV000137139] Chr7:37303478..48660738 [GRCh38]
Chr7:37343082..48700334 [GRCh37]
Chr7:37309607..48670880 [NCBI36]
Chr7:7p14.1-12.3		 pathogenic
GRCh38/hg38 7p14.2-14.1(chr7:35460776-42013800)x1 copy number loss See cases [RCV000138190] Chr7:35460776..42013800 [GRCh38]
Chr7:35500386..42053399 [GRCh37]
Chr7:35466911..42019924 [NCBI36]
Chr7:7p14.2-14.1		 pathogenic
GRCh38/hg38 7p14.3-14.1(chr7:32678391-41044983)x1 copy number loss See cases [RCV000140283] Chr7:32678391..41044983 [GRCh38]
Chr7:32718003..41084581 [GRCh37]
Chr7:32684528..41051106 [NCBI36]
Chr7:7p14.3-14.1		 pathogenic
GRCh38/hg38 7p14.1-13(chr7:38177999-45304100)x1 copy number loss See cases [RCV000142297] Chr7:38177999..45304100 [GRCh38]
Chr7:38217601..45343699 [GRCh37]
Chr7:38184126..45310224 [NCBI36]
Chr7:7p14.1-13		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:152
Count of miRNA genes:146
Interacting mature miRNAs:152
Transcripts:ENST00000420243
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 6 3 2 7 2 8 1 1 11 30
Low 59 7 31 26 29 28 157 12 37 26 121 100 3 2 3 4
Below cutoff 199 145 88 55 54 49 200 23 664 27 319 51 6 24 102

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000420243
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl738,980,370 - 39,013,551 (-)Ensembl
RefSeq Acc Id: NR_138047
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38738,979,895 - 39,013,567 (-)NCBI
T2T-CHM13v2.0739,136,920 - 39,170,597 (-)NCBI
Sequence:
Promoters
RGD ID:15096141
Promoter ID:EPDNEWNC_H962
Type:initiation region
Name:POU6F2-AS2_1
Description:POU6F2 antisense RNA 2 [Source:HGNC Symbol;Acc:HGNC:21887]
SO ACC ID:SO:0000170
Source:EPDNEWNC (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38739,013,553 - 39,013,613EPDNEWNC

Additional Information

Database Acc Id Source(s)
COSMIC POU6F2-AS2 COSMIC
Ensembl Genes ENSG00000233854 Ensembl
GTEx ENSG00000233854 GTEx
HGNC ID HGNC:21887 ENTREZGENE
Human Proteome Map POU6F2-AS2 Human Proteome Map
NCBI Gene POU6F2-AS2 ENTREZGENE
RNAcentral URS0000A76D4A RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-08-21 POU6F2-AS2  POU6F2 antisense RNA 2  POU6F2-AS2  POU6F2 antisense RNA 2 (non-protein coding)  Symbol and/or name change 5135510 APPROVED