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Gene: Ptges (prostaglandin E synthase) Mus musculus
Symbol: Ptges
Name: prostaglandin E synthase
Description: Exhibits prostaglandin-D synthase activity. Involved in negative regulation of cell population proliferation and prostaglandin biosynthetic process. Localizes to cytoplasm and nuclear envelope lumen. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human PTGES (prostaglandin E synthase); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; INTERACTS WITH (+)-pilocarpine; (S)-nicotine; 1,1-dichloroethene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410099E23Rik; D2Ertd369e; microsomal prostaglandin E synthase 1; mPGES; mPGES-1; Pges
Homo sapiens (human) : PTGES (prostaglandin E synthase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ptges (prostaglandin E synthase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptges (prostaglandin E synthase)
Pan paniscus (bonobo/pygmy chimpanzee) : PTGES (prostaglandin E synthase)
Canis lupus familiaris (dog) : PTGES (prostaglandin E synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptges (prostaglandin E synthase)
Sus scrofa (pig) : PTGES (prostaglandin E synthase)
Chlorocebus sabaeus (African green monkey) : PTGES (prostaglandin E synthase)
Heterocephalus glaber (naked mole-rat) : Ptges (prostaglandin E synthase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl230,889,471 - 30,929,863 (-)EnsemblGRCm38mm10GRCm38
GRCm38230,889,471 - 30,931,020 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37230,744,991 - 30,758,817 (-)NCBIGRCm37mm9NCBIm37
MGSCv36230,711,480 - 30,725,306 (-)NCBImm8
Celera230,594,839 - 30,608,694 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map221.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ptges
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62368
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.