Inhba (inhibin beta-A) - Rat Genome Database

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Gene: Inhba (inhibin beta-A) Mus musculus
Analyze
Symbol: Inhba
Name: inhibin beta-A
RGD ID: 62366
MGI Page MGI
Description: Enables signaling receptor binding activity. Involved in eyelid development in camera-type eye; positive regulation of DNA-templated transcription; and positive regulation of ovulation. Acts upstream of or within hematopoietic progenitor cell differentiation; mesodermal cell differentiation; and positive regulation of transcription by RNA polymerase II. Located in perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; early conceptus; embryo mesenchyme; heart; and reproductive system. Orthologous to human INHBA (inhibin subunit beta A).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: activin A; activin beta-A chain; inhibin beta A chain
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391316,178,841 - 16,206,194 (+)NCBIGRCm39mm39
GRCm39 Ensembl1316,186,436 - 16,206,206 (+)Ensembl
GRCm381316,004,256 - 16,031,609 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1316,011,851 - 16,031,621 (+)EnsemblGRCm38mm10GRCm38
MGSCv371316,106,308 - 16,119,044 (+)NCBIGRCm37mm9NCBIm37
MGSCv361315,805,362 - 15,818,098 (+)NCBImm8
Celera1316,301,736 - 16,314,777 (+)NCBICelera
Cytogenetic Map13A1NCBI
cM Map135.85NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-amphetamine  (EXP)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1-chloro-2,4-dinitrobenzene  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2-nitrotoluene  (EXP)
25-hydroxycholesterol  (ISO)
3',5'-cyclic AMP  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-Nitrobenzanthrone  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP)
4-methylcatechol  (ISO)
4-nitrotoluene  (EXP)
5-aza-2'-deoxycytidine  (EXP)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (EXP)
allethrin  (ISO)
alpha-pinene  (ISO)
amiodarone  (EXP)
ammonium chloride  (ISO)
aristolochic acid  (ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
belinostat  (ISO)
benzalkonium chloride  (EXP)
benzo[a]pyrene  (EXP,ISO)
Benzo[ghi]perylene  (EXP)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bromobenzene  (ISO)
buspirone  (ISO)
busulfan  (ISO)
butanal  (ISO)
C60 fullerene  (ISO)
cadmium atom  (ISO)
calcitriol  (ISO)
capsaicin  (ISO)
carbon nanotube  (EXP,ISO)
carmustine  (ISO)
CGP 52608  (ISO)
CHIR 99021  (ISO)
chlordecone  (EXP)
cholesterol  (ISO)
chromium(6+)  (EXP)
ciguatoxin CTX1B  (EXP)
cisplatin  (EXP,ISO)
cobalt atom  (ISO)
colforsin daropate hydrochloride  (ISO)
crocidolite asbestos  (EXP,ISO)
crotonaldehyde  (ISO)
cyclosporin A  (ISO)
cyhalothrin  (ISO)
cypermethrin  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dichlorine  (ISO)
diethylstilbestrol  (EXP,ISO)
diisononyl phthalate  (ISO)
dimethylselenide  (ISO)
dioxygen  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
ethanol  (EXP)
eugenol  (EXP)
fenthion  (EXP)
fenvalerate  (ISO)
formaldehyde  (ISO)
furan  (ISO)
geldanamycin  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glyphosate  (ISO)
graphite  (ISO)
hydroquinone  (ISO)
indometacin  (ISO)
isoflavones  (ISO)
ketamine  (ISO)
L-ascorbic acid  (ISO)
L-ascorbic acid 2-phosphate  (ISO)
lead diacetate  (EXP)
lipopolysaccharide  (ISO)
maneb  (EXP)
methotrexate  (EXP)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
mifepristone  (ISO)
N-nitrosodiethylamine  (ISO)
naproxen  (ISO)
nefazodone  (ISO)
neomycin  (EXP)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
nimesulide  (ISO)
nitrofen  (ISO)
O-methyleugenol  (EXP,ISO)
ochratoxin A  (ISO)
oxazepam  (EXP)
ozone  (EXP,ISO)
p-toluidine  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
PCB138  (ISO)
PD 0325901  (ISO)
pentane-2,3-dione  (ISO)
pepstatin A  (ISO)
perfluorooctanoic acid  (ISO)
phenformin  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP,ISO)
potassium dichromate  (EXP)
progesterone  (EXP,ISO)
propanal  (ISO)
pyridaben  (EXP)
raloxifene  (ISO)
reactive oxygen species  (ISO)
resveratrol  (EXP)
rotenone  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
sevoflurane  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (ISO)
sodium dichromate  (EXP,ISO)
sumatriptan  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP,ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
toluene 2,4-diisocyanate  (EXP)
topotecan  (ISO)
torcetrapib  (ISO)
tremolite asbestos  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
Tungsten carbide  (ISO)
tunicamycin  (ISO)
valproic acid  (EXP,ISO)
valsartan  (ISO)
vincaleukoblastine  (ISO)
XAV939  (ISO)
xylitol  (ISO)
zearalenone  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activin receptor signaling pathway  (ISO)
cardiac fibroblast cell development  (ISO)
cellular response to angiotensin  (ISO)
cellular response to cholesterol  (ISO)
cellular response to follicle-stimulating hormone stimulus  (ISO)
endodermal cell differentiation  (ISO)
extrinsic apoptotic signaling pathway  (ISO)
eyelid development in camera-type eye  (IGI)
GABAergic neuron differentiation  (ISO)
hair follicle development  (ISO)
hematopoietic progenitor cell differentiation  (IDA,ISO)
hemoglobin biosynthetic process  (ISO)
male gonad development  (ISO)
mesoderm formation  (IDA)
mesodermal cell differentiation  (IDA)
multicellular organism aging  (ISO)
negative regulation of cell growth  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of G1/S transition of mitotic cell cycle  (ISO)
negative regulation of hair follicle development  (ISO)
odontogenesis  (ISO)
ovarian follicle development  (ISO)
positive regulation of collagen biosynthetic process  (ISO)
positive regulation of DNA-templated transcription  (IGI,ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of erythrocyte differentiation  (ISO)
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of ovulation  (IMP)
positive regulation of pathway-restricted SMAD protein phosphorylation  (IBA,ISO)
positive regulation of protein metabolic process  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of transcription by RNA polymerase II  (IDA,ISO)
positive regulation of transcription by RNA polymerase III  (ISO)
progesterone secretion  (ISO)
regulation of follicle-stimulating hormone secretion  (ISO)
regulation of transcription by RNA polymerase II  (ISO)
response to xenobiotic stimulus  (ISO)
roof of mouth development  (ISO)
SMAD protein signal transduction  (IBA)
striatal medium spiny neuron differentiation  (ISO)
transcription by RNA polymerase II  (IDA)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal alveolar process morphology  (IAGP)
abnormal circulating hormone level  (IAGP)
abnormal epididymis epithelium morphology  (IAGP)
abnormal epididymis morphology  (IAGP)
abnormal ovarian follicle morphology  (IAGP)
abnormal pectoral muscle morphology  (IAGP)
abnormal seminiferous tubule morphology  (IAGP)
abnormal tertiary ovarian follicle morphology  (IAGP)
abnormal vibrissa follicle morphology  (IAGP)
abnormal Wolffian duct morphology  (IAGP)
absent hard palate  (IAGP)
absent incisors  (IAGP)
absent lower incisors  (IAGP)
absent oocytes  (IAGP)
absent suckling reflex  (IAGP)
absent vibrissae  (IAGP)
anemia  (IAGP)
cachexia  (IAGP)
cleft secondary palate  (IAGP)
decreased body size  (IAGP)
decreased circulating estradiol level  (IAGP)
decreased circulating progesterone level  (IAGP)
decreased hematocrit  (IAGP)
decreased litter size  (IAGP)
decreased mature ovarian follicle number  (IAGP)
decreased secondary ovarian follicle number  (IAGP)
decreased testis weight  (IAGP)
delayed male fertility  (IAGP)
enlarged clitoris  (IAGP)
enlarged external male genitalia  (IAGP)
enophthalmos  (IAGP)
eyelids open at birth  (IAGP)
female infertility  (IAGP)
hypoglycemia  (IAGP)
increased body weight  (IAGP)
increased circulating follicle stimulating hormone level  (IAGP)
increased corpora lutea number  (IAGP)
increased follicle stimulating hormone level  (IAGP)
increased gastrocnemius weight  (IAGP)
increased ovary weight  (IAGP)
increased quadriceps weight  (IAGP)
increased skeletal muscle weight  (IAGP)
large penis  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
ovarian follicular cyst  (IAGP)
polyovular ovarian follicle  (IAGP)
premature death  (IAGP)
reduced female fertility  (IAGP)
retarded hair growth  (IAGP)
rough coat  (IAGP)
short hair  (IAGP)
small ovary  (IAGP)
sparse hair  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Inhibin/activin subunits beta-A (-betaA) and beta-B (-betaB) are differentially localised in normal, hyperplastic and malignant human endometrial tissue. Mylonas I, etal., Acta Histochem. 2006;108(1):1-11. Epub 2006 Jan 19.
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. Abnormal concentration of maternal serum activin-A in gestational diseases. Petraglia F, etal., J Clin Endocrinol Metab. 1995 Feb;80(2):558-61.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Predicting complications of pregnancy with first-trimester maternal serum free-betahCG, PAPP-A and inhibin-A. Tul N, etal., Prenat Diagn. 2003 Dec 15;23(12):990-6.
Additional References at PubMed
PMID:1330789   PMID:1373953   PMID:1646080   PMID:2133547   PMID:2307475   PMID:2767687   PMID:3754442   PMID:7577669   PMID:7600958   PMID:7619733   PMID:7720655   PMID:7799920  
PMID:7821227   PMID:7885473   PMID:8133077   PMID:8286599   PMID:8330535   PMID:8358176   PMID:8406449   PMID:8544842   PMID:8586443   PMID:8606007   PMID:8606941   PMID:8679697  
PMID:8833235   PMID:8838799   PMID:8889548   PMID:8941337   PMID:9027500   PMID:9070865   PMID:9226441   PMID:9326894   PMID:9482661   PMID:9530515   PMID:9655803   PMID:9707328  
PMID:9716414   PMID:9828086   PMID:10349636   PMID:10391928   PMID:10607900   PMID:10662502   PMID:10932194   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11451588   PMID:11557891  
PMID:11697793   PMID:11714685   PMID:11973284   PMID:12477932   PMID:12514121   PMID:12626524   PMID:12666204   PMID:12682233   PMID:12799303   PMID:14527958   PMID:14551263   PMID:14678255  
PMID:14736745   PMID:14960276   PMID:14973287   PMID:15136142   PMID:15277382   PMID:15304227   PMID:15305290   PMID:15342483   PMID:15489334   PMID:15525533   PMID:15747579   PMID:15963767  
PMID:15963972   PMID:16112648   PMID:16141072   PMID:16141073   PMID:16183868   PMID:16452457   PMID:16524929   PMID:16601134   PMID:16602821   PMID:16772531   PMID:16873442   PMID:16890158  
PMID:17071781   PMID:17082592   PMID:17478422   PMID:17592132   PMID:17609433   PMID:17881772   PMID:17951260   PMID:18089557   PMID:18093225   PMID:18177426   PMID:18225977   PMID:18310445  
PMID:18321725   PMID:18353928   PMID:18382659   PMID:18406693   PMID:18922734   PMID:18927237   PMID:18945958   PMID:19079322   PMID:19095948   PMID:19136618   PMID:19342638   PMID:19389832  
PMID:19435857   PMID:19517569   PMID:19587158   PMID:19591819   PMID:19716815   PMID:19805648   PMID:20130270   PMID:20194748   PMID:20498064   PMID:20530870   PMID:20689039   PMID:20810712  
PMID:20926807   PMID:21084447   PMID:21267068   PMID:21300867   PMID:21308778   PMID:21338885   PMID:21402782   PMID:21408162   PMID:21445090   PMID:21658586   PMID:21727023   PMID:21852401  
PMID:21873635   PMID:21952240   PMID:22161160   PMID:22405202   PMID:22425773   PMID:22560297   PMID:22629441   PMID:22682244   PMID:22739106   PMID:22847922   PMID:22869749   PMID:22982176  
PMID:23117933   PMID:23178301   PMID:23221368   PMID:23303681   PMID:23342175   PMID:23431057   PMID:23441037   PMID:23471215   PMID:23497137   PMID:23525041   PMID:23684768   PMID:23831638  
PMID:23916668   PMID:24006456   PMID:24139759   PMID:24378873   PMID:24462039   PMID:24552588   PMID:24655377   PMID:24859004   PMID:24952961   PMID:25052838   PMID:25082703   PMID:25261715  
PMID:25344072   PMID:25413949   PMID:25775517   PMID:25902062   PMID:26215835   PMID:26608361   PMID:26874185   PMID:27328730   PMID:27465829   PMID:28178568   PMID:28202523   PMID:28214591  
PMID:28558017   PMID:28605600   PMID:28639003   PMID:28758906   PMID:28760667   PMID:28781074   PMID:29030492   PMID:29031500   PMID:29174564   PMID:30074079   PMID:30093305   PMID:30635555  
PMID:31187730   PMID:31242421   PMID:31492508   PMID:31676717   PMID:32074129   PMID:32274496   PMID:32451392   PMID:33130539   PMID:33172478   PMID:33219121   PMID:33382037   PMID:33421362  
PMID:34155146   PMID:34288113   PMID:34376651   PMID:34385332   PMID:34731499   PMID:35042829   PMID:35084365   PMID:35102236   PMID:35721752  


Genomics

Comparative Map Data
Inhba
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391316,178,841 - 16,206,194 (+)NCBIGRCm39mm39
GRCm39 Ensembl1316,186,436 - 16,206,206 (+)Ensembl
GRCm381316,004,256 - 16,031,609 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1316,011,851 - 16,031,621 (+)EnsemblGRCm38mm10GRCm38
MGSCv371316,106,308 - 16,119,044 (+)NCBIGRCm37mm9NCBIm37
MGSCv361315,805,362 - 15,818,098 (+)NCBImm8
Celera1316,301,736 - 16,314,777 (+)NCBICelera
Cytogenetic Map13A1NCBI
cM Map135.85NCBI
INHBA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38741,685,114 - 41,705,406 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl741,667,168 - 41,705,834 (-)EnsemblGRCh38hg38GRCh38
GRCh37741,724,712 - 41,742,688 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36741,695,126 - 41,709,231 (-)NCBINCBI36hg18NCBI36
Build 34741,502,035 - 41,513,299NCBI
Celera741,719,390 - 41,733,490 (-)NCBI
Cytogenetic Map7p14.1NCBI
HuRef741,613,504 - 41,627,622 (-)NCBIHuRef
CHM1_1741,731,917 - 41,746,019 (-)NCBICHM1_1
T2T-CHM13v2.0741,843,512 - 41,861,485 (-)NCBI
CRA_TCAGchr7v2741,768,467 - 41,782,571 (-)NCBI
Inhba
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21749,091,635 - 49,111,573 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1749,095,920 - 49,108,982 (-)Ensembl
Rnor_6.01751,894,869 - 51,919,998 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1751,898,217 - 51,912,496 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01749,961,222 - 49,985,653 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41757,244,466 - 57,257,531 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11757,247,306 - 57,260,372 (-)NCBI
Celera1745,163,387 - 45,176,397 (-)NCBICelera
Cytogenetic Map17q12.1NCBI
Inhba
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554602,046,588 - 2,066,609 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554602,054,879 - 2,066,628 (+)NCBIChiLan1.0ChiLan1.0
INHBA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1742,580,730 - 42,598,712 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl742,580,730 - 42,595,097 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0742,538,591 - 42,556,578 (+)NCBIMhudiblu_PPA_v0panPan3
INHBA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1188,272,978 - 8,288,432 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl188,272,872 - 8,283,794 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha188,122,697 - 8,138,128 (+)NCBI
ROS_Cfam_1.0188,321,520 - 8,336,958 (+)NCBI
ROS_Cfam_1.0 Ensembl188,318,003 - 8,332,480 (+)Ensembl
UMICH_Zoey_3.1188,301,757 - 8,317,182 (+)NCBI
UNSW_CanFamBas_1.0188,269,907 - 8,285,348 (+)NCBI
UU_Cfam_GSD_1.0188,385,256 - 8,400,687 (+)NCBI
Inhba
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511897,666,669 - 97,672,334 (-)NCBI
SpeTri2.0NW_00493647816,878,725 - 16,884,065 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INHBA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1852,889,684 - 52,900,967 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11253,115,379 - 53,117,128 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11852,889,684 - 52,909,260 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21857,997,858 - 58,017,387 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.21255,481,493 - 55,483,255 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap18q24NCBI
INHBA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12116,936,054 - 16,951,430 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2116,936,175 - 16,946,880 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660625,522,195 - 5,540,211 (-)NCBIVero_WHO_p1.0
Inhba
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474019,464,289 - 19,482,888 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462474019,458,835 - 19,482,570 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
Inhba  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381316,026,941 - 16,027,155UniSTSGRCm38
MGSCv371316,118,774 - 16,118,988UniSTSGRCm37
Celera1316,314,507 - 16,314,721UniSTS
Cytogenetic Map13A1UniSTS
cM Map1310.0UniSTS
cM Map1310.0UniSTS
cM Map1310.0UniSTS
Inhba  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A1UniSTS
Inhba  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A1UniSTS
cM Map1310.0UniSTS
Inhba  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381316,026,599 - 16,027,120UniSTSGRCm38
MGSCv371316,118,432 - 16,118,953UniSTSGRCm37
Celera1316,314,165 - 16,314,686UniSTS
Cytogenetic Map13A1UniSTS
cM Map1310.0UniSTS


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301890Adip7_madiposity 7 (mouse)Not determined13123454672Mouse
1301227Skull19_mskull morphology 19 (mouse)Not determined13123454672Mouse
1301661Tshp13_mtooth shape 13 (mouse)Not determined13123454672Mouse
1301255Cd4ts6_mCD4 T cell subset 6 (mouse)Not determined1316854534168684Mouse
10449140Eosn2_meosinophil differential 2 (mouse)1322131134221311Mouse
15039338Nmrs34_mNAFLD-associated magnetic resonance shift 34 (mouse)1322131134221311Mouse
1301455Bmd3_mbone mineral density 3 (mouse)Not determined13347761237477820Mouse
10045624Heal24_mwound healing/regeneration (mouse)Not determined13347761237477820Mouse
10045625Heal23_mwound healing/regeneration 23 (mouse)Not determined13347761237477820Mouse
1301367Twq1_mtestis weight QTL 1 (mouse)Not determined13361551237615672Mouse
1301733Heal3_mwound healing/regeneration 3 (mouse)Not determined13368020037680343Mouse
26884393Humsd7_mhumerus midshaft diameter 7, 16 week (mouse)13395000076048119Mouse
1558898Hpi1_mhapatic PMN infiltration 1 (mouse)Not determined13441402553101640Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir503mmu-miR-503-5pMirtarbaseexternal_infoqRT-PCRNon-Functional MTI (Weak)19799966

Predicted Target Of
Summary Value
Count of predictions:260
Count of miRNA genes:152
Interacting mature miRNAs:160
Transcripts:ENSMUST00000042603, ENSMUST00000164993
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000042603   ⟹   ENSMUSP00000047894
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1316,186,436 - 16,206,206 (+)Ensembl
GRCm38.p6 Ensembl1316,011,851 - 16,031,621 (+)Ensembl
RefSeq Acc Id: ENSMUST00000164993   ⟹   ENSMUSP00000132085
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1316,189,060 - 16,201,796 (+)Ensembl
GRCm38.p6 Ensembl1316,014,475 - 16,027,211 (+)Ensembl
RefSeq Acc Id: NM_008380   ⟹   NP_032406
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391316,186,436 - 16,206,194 (+)NCBI
GRCm381316,011,851 - 16,031,609 (+)NCBI
MGSCv371316,106,308 - 16,119,044 (+)RGD
Celera1316,301,736 - 16,314,777 (+)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006516559   ⟹   XP_006516622
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391316,185,144 - 16,206,194 (+)NCBI
GRCm381316,004,256 - 16,031,609 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011244285   ⟹   XP_011242587
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391316,178,841 - 16,206,194 (+)NCBI
GRCm381316,004,256 - 16,031,609 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032406   ⟸   NM_008380
- Peptide Label: preproprotein
- UniProtKB: Q04998 (UniProtKB/Swiss-Prot),   Q3UY39 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006516622   ⟸   XM_006516559
- Peptide Label: isoform X1
- UniProtKB: Q04998 (UniProtKB/Swiss-Prot),   Q3UY39 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011242587   ⟸   XM_011244285
- Peptide Label: isoform X1
- UniProtKB: Q04998 (UniProtKB/Swiss-Prot),   Q3UY39 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000132085   ⟸   ENSMUST00000164993
RefSeq Acc Id: ENSMUSP00000047894   ⟸   ENSMUST00000042603
Protein Domains
TGF_BETA_2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q04998-F1-model_v2 AlphaFold Q04998 1-424 view protein structure

Promoters
RGD ID:8679634
Promoter ID:EPDNEW_M17848
Type:initiation region
Name:Inhba_1
Description:Mus musculus inhibin beta-A , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M17849  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381316,014,466 - 16,014,526EPDNEW
RGD ID:8679636
Promoter ID:EPDNEW_M17849
Type:initiation region
Name:Inhba_2
Description:Mus musculus inhibin beta-A , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M17848  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381316,017,095 - 16,017,155EPDNEW
RGD ID:6824067
Promoter ID:MM_KWN:13292
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000042603
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361316,103,296 - 16,103,897 (+)MPROMDB
RGD ID:6824069
Promoter ID:MM_KWN:13293
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B4,   MEF_B6
Transcripts:UC007PNW.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361316,105,396 - 16,106,407 (+)MPROMDB
RGD ID:6847034
Promoter ID:MM_ACW:12554
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B4,   MEF_B6
Transcripts:INHBA.CSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361316,108,951 - 16,109,451 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96570 AgrOrtholog
Ensembl Genes ENSMUSG00000041324 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000047894 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000132085 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000042603 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000164993 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.10.90.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cystine-knot_cytokine UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Inhibin_betaA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGF-b_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGF-b_propeptide UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGF-beta-rel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGFb_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16323 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:96570 ENTREZGENE
NCBI Gene 16323 ENTREZGENE
PANTHER PTHR11848 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TGF_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGFb_propeptide UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Inhba PhenoGen
PRINTS INHIBINBA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TGF_BETA_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGF_BETA_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART TGFB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57501 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt INHBA_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3UXL8_MOUSE UniProtKB/TrEMBL
  Q3UY39 ENTREZGENE, UniProtKB/TrEMBL
  Q4FJM4_MOUSE UniProtKB/TrEMBL