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Gene: P2rx4 (purinergic receptor P2X, ligand-gated ion channel 4) Mus musculus
Symbol: P2rx4
Name: purinergic receptor P2X, ligand-gated ion channel 4
Description: Exhibits extracellularly ATP-gated cation channel activity. Involved in several processes, including excitatory postsynaptic potential; nitric oxide biosynthetic process; and vasodilation. Localizes to apical part of cell. Is expressed in several structures, including cardiovascular system; gut; immune system; nervous system; and viscerocranium. Orthologous to human P2RX4 (purinergic receptor P2X 4); INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI504491; ATP receptor; AW555605; D5Ertd444e; ionotropic purinergic receptor; P2X purinoceptor 4; P2X4; purinergic receptor P2x4 subunit variant e
Homo sapiens (human) : P2RX4 (purinergic receptor P2X 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : P2rx4 (purinergic receptor P2X 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : P2rx4 (purinergic receptor P2X 4)
Pan paniscus (bonobo/pygmy chimpanzee) : P2RX4 (purinergic receptor P2X 4)
Canis lupus familiaris (dog) : P2RX4 (purinergic receptor P2X 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P2rx4 (purinergic receptor P2X 4)
Sus scrofa (pig) : P2RX4 (purinergic receptor P2X 4)
Chlorocebus sabaeus (African green monkey) : P2RX4 (purinergic receptor P2X 4)
Heterocephalus glaber (naked mole-rat) : P2rx4 (purinergic receptor P2X 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl5122,707,544 - 122,729,738 (+)EnsemblGRCm38mm10GRCm38
GRCm385122,707,518 - 122,729,739 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375123,157,566 - 123,179,053 (+)NCBIGRCm37mm9NCBIm37
MGSCv365122,968,240 - 122,989,661 (+)NCBImm8
Celera5119,785,375 - 119,806,787 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map562.53NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on P2rx4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62365
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.