Rpl29 (ribosomal protein L29) - Rat Genome Database
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Gene: Rpl29 (ribosomal protein L29) Mus musculus
Analyze
Symbol: Rpl29
Name: ribosomal protein L29
RGD ID: 62361
MGI Page MGI
Description: Exhibits heparin binding activity. Involved in several processes, including cell population proliferation; cell-substrate adhesion; and translation. Localizes to extrinsic component of membrane; ribosome; and synapse. Is expressed in several structures, including gonad; heart; liver; lung; and metanephros. Orthologous to human RPL29 (ribosomal protein L29); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 60S ribosomal protein L29; MGC107574; MGC107575; MGC107576; Rp; Rpl43
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm10548   Gm10709   Gm11270   Gm13841   Gm15454   Gm3550   Gm4889   Gm4945   Gm5561   Gm6344   Gm8210   Gm8580   Rpl29-ps1   Rpl29-ps2   Rpl29-ps4   Rpl29-ps5   Rpl29-ps6  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399106,306,610 - 106,308,767 (+)NCBIGRCm39mm39
GRCm389106,428,889 - 106,431,568 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9106,429,454 - 106,431,568 (+)EnsemblGRCm38mm10GRCm38
MGSCv379106,331,870 - 106,333,898 (+)NCBIGRCm37mm9NCBIm37
MGSCv369106,287,640 - 106,289,668 (+)NCBImm8
Celera9106,056,937 - 106,058,955 (+)NCBICelera
Cytogenetic Map9F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:8224911   PMID:9737974   PMID:10349636   PMID:10922068   PMID:10964519   PMID:11042159   PMID:11076861   PMID:11259264   PMID:11803571   PMID:12477932   PMID:12919102   PMID:14610273  
PMID:15489334   PMID:16141072   PMID:16141073   PMID:16452087   PMID:17195189   PMID:18661500   PMID:18799693   PMID:20362701   PMID:21267068   PMID:21529712   PMID:21873635   PMID:22001906  
PMID:22198155   PMID:23118343   PMID:23665500   PMID:26336360   PMID:28378742   PMID:30196744   PMID:30457570   PMID:30562941   PMID:32098917   PMID:32325033   PMID:33004906  


Genomics

Comparative Map Data
Rpl29
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399106,306,610 - 106,308,767 (+)NCBIGRCm39mm39
GRCm389106,428,889 - 106,431,568 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9106,429,454 - 106,431,568 (+)EnsemblGRCm38mm10GRCm38
MGSCv379106,331,870 - 106,333,898 (+)NCBIGRCm37mm9NCBIm37
MGSCv369106,287,640 - 106,289,668 (+)NCBImm8
Celera9106,056,937 - 106,058,955 (+)NCBICelera
Cytogenetic Map9F1NCBI
RPL29
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl351,993,522 - 51,995,895 (-)EnsemblGRCh38hg38GRCh38
GRCh38351,993,522 - 51,995,895 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37352,027,644 - 52,029,958 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36352,002,684 - 52,004,998 (-)NCBINCBI36hg18NCBI36
Build 34352,002,684 - 52,004,998NCBI
Celera352,006,920 - 52,009,228 (-)NCBI
Cytogenetic Map3p21.2NCBI
HuRef352,090,984 - 52,093,304 (-)NCBIHuRef
CHM1_1351,980,247 - 51,982,561 (-)NCBICHM1_1
Rpl29
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08115,131,228 - 115,133,401 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8115,131,367 - 115,133,401 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08114,495,464 - 114,497,498 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48111,573,459 - 111,575,493 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18111,592,913 - 111,594,948 (+)NCBI
Celera8106,380,871 - 106,382,905 (+)NCBICelera
Cytogenetic Map8q32NCBI
Rpl29
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555323,633,377 - 3,635,590 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555323,633,260 - 3,636,068 (-)NCBIChiLan1.0ChiLan1.0
RPL29
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Mhudiblu_PPA_v0351,935,053 - 51,937,412 (-)NCBIMhudiblu_PPA_v0panPan3
RPL29
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12037,727,161 - 37,729,738 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Rpl29
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365293,337,056 - 3,339,683 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPL29
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1334,119,538 - 34,121,907 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11334,119,541 - 34,121,842 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21337,316,234 - 37,318,518 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap13q21-q22NCBI
RPL29
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12213,362,348 - 13,365,013 (-)NCBI
Rpl29
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247305,807,029 - 5,810,138 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959990000109260000Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
1301573Etohcta8_methanol conditioned taste aversion 8 (mouse)Not determined972977005106977152Mouse
10054068El8_mepilepsy 8 (mouse)Not determined972977005106977152Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974368177108368325Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975775364114474379Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975775364114474379Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976535936110536130Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978640645112640755Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979397810113397888Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981798268115798392Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982910333116910428Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982910333116910428Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982910333116910428Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984528818118528921Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985897510108641186Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986230401120230530Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986239845120289624Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986748483120748483Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987800000121800000Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989977005118938021Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994981301112872929Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9101060861124595110Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9102000187124595110Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9102000187124595110Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103289445124595110Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103289445124595110Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103289445124595110Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:283
Count of miRNA genes:129
Interacting mature miRNAs:139
Transcripts:ENSMUST00000059802, ENSMUST00000150576
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001324533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001324534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006511660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC151729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF236069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC019179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC081467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC082292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC086897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC086898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC087950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC092262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC094039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC096575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY002054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L08651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000059802   ⟹   ENSMUSP00000080203
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9106,429,539 - 106,431,567 (+)Ensembl
RefSeq Acc Id: ENSMUST00000098994   ⟹   ENSMUSP00000096592
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9106,429,538 - 106,431,508 (+)Ensembl
RefSeq Acc Id: ENSMUST00000150576   ⟹   ENSMUSP00000117834
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9106,429,454 - 106,431,568 (+)Ensembl
RefSeq Acc Id: ENSMUST00000213448   ⟹   ENSMUSP00000149722
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9106,429,555 - 106,431,388 (+)Ensembl
RefSeq Acc Id: ENSMUST00000214067   ⟹   ENSMUSP00000150846
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9106,431,069 - 106,431,567 (+)Ensembl
RefSeq Acc Id: ENSMUST00000217081   ⟹   ENSMUSP00000150339
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9106,429,562 - 106,431,172 (+)Ensembl
RefSeq Acc Id: NM_001324533   ⟹   NP_001311462
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399106,306,610 - 106,308,767 (+)NCBI
GRCm389106,429,411 - 106,431,568 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001324534   ⟹   NP_001311463
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399106,306,610 - 106,308,767 (+)NCBI
GRCm389106,429,411 - 106,431,568 (+)NCBI
Sequence:
RefSeq Acc Id: NM_009082   ⟹   NP_033108
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399106,306,610 - 106,308,767 (+)NCBI
GRCm389106,429,411 - 106,431,568 (+)NCBI
MGSCv379106,331,870 - 106,333,898 (+)RGD
Celera9106,056,937 - 106,058,955 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006511660   ⟹   XP_006511723
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399106,306,631 - 106,308,767 (+)NCBI
GRCm389106,428,889 - 106,431,568 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033108   ⟸   NM_009082
- UniProtKB: P47915 (UniProtKB/Swiss-Prot),   Q5M8M8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006511723   ⟸   XM_006511660
- Peptide Label: isoform X1
- UniProtKB: P47915 (UniProtKB/Swiss-Prot),   Q5M8M8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001311463   ⟸   NM_001324534
- UniProtKB: P47915 (UniProtKB/Swiss-Prot),   Q5M8M8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001311462   ⟸   NM_001324533
- UniProtKB: P47915 (UniProtKB/Swiss-Prot),   Q5M8M8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000117834   ⟸   ENSMUST00000150576
RefSeq Acc Id: ENSMUSP00000150339   ⟸   ENSMUST00000217081
RefSeq Acc Id: ENSMUSP00000080203   ⟸   ENSMUST00000059802
RefSeq Acc Id: ENSMUSP00000096592   ⟸   ENSMUST00000098994
RefSeq Acc Id: ENSMUSP00000149722   ⟸   ENSMUST00000213448
RefSeq Acc Id: ENSMUSP00000150846   ⟸   ENSMUST00000214067

Promoters
RGD ID:6845128
Promoter ID:MM_KWN:58664
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_009082,   OTTMUST00000085045
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv369106,331,519 - 106,332,019 (+)MPROMDB
RGD ID:8670722
Promoter ID:EPDNEW_M13392
Type:initiation region
Name:Rpl29-2_1
Description:Mus musculus ribosomal protein L29 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389106,429,532 - 106,429,592EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:99687 AgrOrtholog
Ensembl Genes ENSMUSG00000048758 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000080203 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000096592 UniProtKB/Swiss-Prot
  ENSMUSP00000117834 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000149722 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000150339 UniProtKB/TrEMBL
  ENSMUSP00000150846 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000059802 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000098994 UniProtKB/Swiss-Prot
  ENSMUST00000150576 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000213448 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000214067 UniProtKB/TrEMBL
  ENSMUST00000217081 UniProtKB/TrEMBL
InterPro Ribosomal_L29e UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19944 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:99687 ENTREZGENE
NCBI Gene 19944 ENTREZGENE
PANTHER PTHR12884 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ribosomal_L29e UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rpl29 PhenoGen
UniGene Mm.288696 ENTREZGENE
  Mm.359377 ENTREZGENE
  Mm.431965 ENTREZGENE
UniProt A0A1L1SS27_MOUSE UniProtKB/TrEMBL
  A0A1L1STJ3_MOUSE UniProtKB/TrEMBL
  A0A1L1SUN1_MOUSE UniProtKB/TrEMBL
  P47915 ENTREZGENE
  Q5M8M8 ENTREZGENE, UniProtKB/TrEMBL
  RL29_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary D3Z1N9 UniProtKB/TrEMBL