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Gene: Aoc3 (amine oxidase, copper containing 3) Mus musculus
Symbol: Aoc3
Name: amine oxidase, copper containing 3
RGD ID: 62350
Description: Predicted to have several functions, including metal ion binding activity; primary amine oxidase activity; and protein heterodimerization activity. Predicted to be involved in several processes, including leukocyte migration involved in inflammatory response; negative regulation of primary amine oxidase activity; and positive regulation of glucose transmembrane transport. Predicted to localize to several cellular components, including Golgi apparatus; early endosome; and microvillus. Is expressed in several structures, including alimentary system; axial skeleton; cardiovascular system; sensory organ; and skin. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human AOC3 (amine oxidase copper containing 3); PARTICIPATES IN beta-alanine metabolic pathway; carnosinemia pathway; GABA aminotransferase deficiency pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: copper amine oxidase; membrane primary amine oxidase; semicarbazide-sensitive amine oxidase; SSAO; V; VAP-1; VAP1; vascular adhesion protein 1
Homo sapiens (human) : AOC3 (amine oxidase copper containing 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Aoc3 (amine oxidase, copper containing 3)  Alliance
Canis lupus familiaris (dog) : AOC3 (amine oxidase copper containing 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aoc3 (amine oxidase copper containing 3)
Sus scrofa (pig) : LOC110256000 (membrane primary amine oxidase-like)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm3911101,221,432 - 101,230,256 (+)NCBI
GRCm3811101,330,606 - 101,339,430 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11101,330,605 - 101,341,938 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711101,191,920 - 101,200,744 (+)NCBIGRCm37mm9NCBIm37
MGSCv3611101,146,696 - 101,155,514 (+)NCBImm8
MGSCv3611102,109,647 - 102,118,471 (+)NCBImm8
Cytogenetic Map11DNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Aoc3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62350
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.