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Gene: Ywhae (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide) Mus musculus
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Symbol: Ywhae
Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
Description: Exhibits protein domain specific binding activity and protein phosphatase binding activity. Involved in several processes, including negative regulation of protein dephosphorylation; neuron migration; and pallium development. Localizes to cytoplasm. Predicted to colocalize with plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study Miller-Dieker lissencephaly syndrome and left ventricular noncompaction. Orthologous to human YWHAE (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; insulin-like growth factor signaling pathway; mTOR signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 14-3-3 epsilon; 14-3-3 protein epsilon; 14-3-3E; AU019196; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activatioprotein, epsilon polypeptide
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1175,732,869 - 75,765,845 (+)EnsemblGRCm38mm10GRCm38
GRCm381175,732,887 - 75,765,841 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371175,546,389 - 75,579,343 (+)NCBIGRCm37mm9NCBIm37
MGSCv361175,549,134 - 75,582,033 (+)NCBImm8
Celera1183,242,083 - 83,275,058 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ywhae
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62292
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.