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Gene: Hpn (hepsin) Mus musculus
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Symbol: Hpn
Name: hepsin
Description: Predicted to have serine-type endopeptidase activity. Involved in several processes, including cholesterol homeostasis; cochlea morphogenesis; and detection of mechanical stimulus involved in sensory perception of sound. Localizes to cell-cell junction; neuronal cell body; and plasma membrane. Predicted to colocalize with nuclear membrane. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; hemolymphoid system gland; and sensory organ. Orthologous to human HPN (hepsin).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AA408042; AI788568; Hlb320; serine protease hepsin
Orthologs:
Homo sapiens (human) : HPN (hepsin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hpn (hepsin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hpn (hepsin)
Pan paniscus (bonobo/pygmy chimpanzee) : HPN (hepsin)
Canis lupus familiaris (dog) : HPN (hepsin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hpn (hepsin)
Sus scrofa (pig) : HPN (hepsin)
Chlorocebus sabaeus (African green monkey) : HPN (hepsin)
Heterocephalus glaber (naked mole-rat) : Hpn (hepsin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl731,098,725 - 31,115,290 (-)EnsemblGRCm38mm10GRCm38
GRCm38731,098,725 - 31,115,326 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37731,883,744 - 31,900,309 (-)NCBIGRCm37mm9NCBIm37
MGSCv36730,807,485 - 30,824,034 (-)NCBImm8
Celera725,667,468 - 25,684,520 (-)NCBICelera
Cytogenetic Map7B1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hpn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62274
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.