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Gene: Hpse (heparanase) Mus musculus
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Symbol: Hpse
Name: heparanase
Description: Predicted to have heparanase activity; protein dimerization activity; and syndecan binding activity. Involved in several processes, including positive regulation of osteoblast proliferation; positive regulation of protein kinase B signaling; and vascular wound healing. Localizes to the membrane raft and nucleus. Is expressed in oral region gland; sensory organ; skeleton; and urinary system. Orthologous to human HPSE (heparanase).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: endo-glucoronidase; endoglycosidase heparanase; Hpa; Hpr1; HSE1
Orthologs:
Homo sapiens (human) : HPSE (heparanase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hpse (heparanase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hpse (heparanase)
Pan paniscus (bonobo/pygmy chimpanzee) : HPSE (heparanase)
Canis lupus familiaris (dog) : HPSE (heparanase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hpse (heparanase)
Sus scrofa (pig) : HPSE (heparanase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm385100,679,484 - 100,719,716 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375101,108,505 - 101,148,702 (-)NCBIGRCm37mm9NCBIm37
MGSCv365100,920,698 - 100,959,985 (-)NCBImm8
Celera598,006,862 - 98,047,031 (-)NCBICelera
Cytogenetic Map5 E4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hpse
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62262
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.