Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Preb (prolactin regulatory element binding) Mus musculus
Symbol: Preb
Name: prolactin regulatory element binding
Description: Exhibits Sar guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including COPII vesicle coating; protein transport; and regulation of COPII vesicle coating. Predicted to localize to endoplasmic reticulum exit site; integral component of endoplasmic reticulum membrane; and nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; jaw; metanephros; and surface ectoderm. Orthologous to human PREB (prolactin regulatory element binding); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C85705; mammalian guanine nucleotide exchange factor mSec12; prolactin regulatory element-binding protein
Homo sapiens (human) : PREB (prolactin regulatory element binding)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Preb (prolactin regulatory element binding)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Preb (prolactin regulatory element binding)
Pan paniscus (bonobo/pygmy chimpanzee) : PREB (prolactin regulatory element binding)
Canis lupus familiaris (dog) : PREB (prolactin regulatory element binding)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Preb (prolactin regulatory element binding)
Sus scrofa (pig) : PREB (prolactin regulatory element binding)
Chlorocebus sabaeus (African green monkey) : PREB (prolactin regulatory element binding)
Heterocephalus glaber (naked mole-rat) : Preb (prolactin regulatory element binding)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl530,950,853 - 30,960,361 (-)EnsemblGRCm38mm10GRCm38
GRCm38530,951,667 - 30,960,356 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37531,254,040 - 31,262,734 (-)NCBIGRCm37mm9NCBIm37
MGSCv36531,231,629 - 31,236,816 (-)NCBImm8
Celera528,431,460 - 28,439,754 (-)NCBICelera
Cytogenetic Map5B1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Preb
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62222
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.