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Gene: Preb (prolactin regulatory element binding) Mus musculus
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Symbol: Preb
Name: prolactin regulatory element binding
Description: Exhibits Sar guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including COPII vesicle coating; protein transport; and regulation of COPII vesicle coating. Predicted to localize to endoplasmic reticulum exit site; integral component of endoplasmic reticulum membrane; and nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; jaw; metanephros; and surface ectoderm. Orthologous to human PREB (prolactin regulatory element binding); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C85705; mammalian guanine nucleotide exchange factor mSec12; prolactin regulatory element-binding protein
Orthologs:
Homo sapiens (human) : PREB (prolactin regulatory element binding)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Preb (prolactin regulatory element binding)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Preb (prolactin regulatory element binding)
Pan paniscus (bonobo/pygmy chimpanzee) : PREB (prolactin regulatory element binding)
Canis lupus familiaris (dog) : PREB (prolactin regulatory element binding)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Preb (prolactin regulatory element binding)
Sus scrofa (pig) : PREB (prolactin regulatory element binding)
Chlorocebus sabaeus (African green monkey) : PREB (prolactin regulatory element binding)
Heterocephalus glaber (naked mole-rat) : Preb (prolactin regulatory element binding)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl530,950,853 - 30,960,361 (-)EnsemblGRCm38mm10GRCm38
GRCm38530,951,667 - 30,960,356 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37531,254,040 - 31,262,734 (-)NCBIGRCm37mm9NCBIm37
MGSCv36531,231,629 - 31,236,816 (-)NCBImm8
Celera528,431,460 - 28,439,754 (-)NCBICelera
Cytogenetic Map5B1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Preb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62222
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.