Dnah1 (dynein, axonemal, heavy chain 1) - Rat Genome Database

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Gene: Dnah1 (dynein, axonemal, heavy chain 1) Rattus norvegicus
Analyze
Symbol: Dnah1
Name: dynein, axonemal, heavy chain 1
RGD ID: 621795
Description: Predicted to enable dynein intermediate chain binding activity; dynein light intermediate chain binding activity; and minus-end-directed microtubule motor activity. Predicted to be involved in inner dynein arm assembly and sperm axoneme assembly. Predicted to act upstream of or within cilium movement involved in cell motility and epithelial cilium movement involved in extracellular fluid movement. Predicted to be located in axoneme and sperm flagellum. Predicted to be part of inner dynein arm. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 37 and spermatogenic failure 18. Orthologous to human DNAH1 (dynein axonemal heavy chain 1); PARTICIPATES IN Huntington's disease pathway; INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: axonemal beta dynein heavy chain 1; ciliary dynein heavy chain 1; Dnahc1; dynein axonemal heavy chain 1; dynein heavy chain 1, axonemal; dynein, axonemal, heavy polypeptide 1; LOC306258; RGD1311110; similar to KIAA1410 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2166,455,514 - 6,517,103 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl166,456,002 - 6,518,350 (-)Ensembl
Rnor_6.0167,345,131 - 7,407,009 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl167,345,978 - 7,408,265 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0167,273,266 - 7,336,037 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4166,693,763 - 6,754,535 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1166,724,485 - 6,726,552 (-)NCBI
Celera168,672,026 - 8,733,031 (+)NCBICelera
Cytogenetic Map16p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axoneme  (ISO,ISS)
cilium  (IEA)
cytoplasm  (IEA)
dynein complex  (IBA,IEA)
extracellular region  (IEA,ISO)
inner dynein arm  (IBA,ISO)
microtubule  (IEA)
sperm flagellum  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Identification and molecular evolution of new dynein-like protein sequences in rat brain. Tanaka Y, etal., J Cell Sci 1995 May;108 ( Pt 5):1883-93.
Additional References at PubMed
PMID:11371505   PMID:24360805   PMID:27798045  


Genomics

Comparative Map Data
Dnah1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2166,455,514 - 6,517,103 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl166,456,002 - 6,518,350 (-)Ensembl
Rnor_6.0167,345,131 - 7,407,009 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl167,345,978 - 7,408,265 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0167,273,266 - 7,336,037 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4166,693,763 - 6,754,535 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1166,724,485 - 6,726,552 (-)NCBI
Celera168,672,026 - 8,733,031 (+)NCBICelera
Cytogenetic Map16p16NCBI
DNAH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38352,310,920 - 52,400,492 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl352,316,319 - 52,400,492 (+)EnsemblGRCh38hg38GRCh38
GRCh37352,350,335 - 52,434,508 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36352,325,560 - 52,409,547 (+)NCBINCBI36hg18NCBI36
Build 34352,370,292 - 52,370,408NCBI
Celera352,329,658 - 52,413,835 (+)NCBI
Cytogenetic Map3p21.1NCBI
HuRef352,412,962 - 52,497,148 (+)NCBIHuRef
CHM1_1352,302,860 - 52,387,039 (+)NCBICHM1_1
T2T-CHM13v2.0352,349,219 - 52,433,474 (+)NCBI
Dnah1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391430,982,332 - 31,045,926 (-)NCBIGRCm39mm39
GRCm39 Ensembl1430,982,332 - 31,045,853 (-)Ensembl
GRCm381431,260,375 - 31,325,891 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1431,260,375 - 31,323,896 (-)EnsemblGRCm38mm10GRCm38
MGSCv371432,073,561 - 32,137,082 (-)NCBIGRCm37mm9NCBIm37
MGSCv361430,089,384 - 30,152,900 (-)NCBImm8
Celera1427,518,985 - 27,582,573 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1419.1NCBI
Dnah1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554302,327,584 - 2,391,423 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554302,323,928 - 2,391,470 (+)NCBIChiLan1.0ChiLan1.0
DNAH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1353,491,822 - 53,572,393 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl353,491,822 - 53,572,393 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0352,233,271 - 52,342,627 (+)NCBIMhudiblu_PPA_v0panPan3
DNAH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12037,364,836 - 37,441,486 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2037,364,842 - 37,465,807 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2037,346,392 - 37,423,030 (-)NCBI
ROS_Cfam_1.02037,714,963 - 37,791,616 (-)NCBI
ROS_Cfam_1.0 Ensembl2037,714,969 - 37,787,882 (-)Ensembl
UMICH_Zoey_3.12037,078,913 - 37,155,548 (-)NCBI
UNSW_CanFamBas_1.02037,487,581 - 37,564,217 (-)NCBI
UU_Cfam_GSD_1.02037,772,261 - 37,848,897 (-)NCBI
Dnah1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118170,027,586 - 170,099,756 (+)NCBI
SpeTri2.0NW_0049364733,170,060 - 3,238,608 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1334,445,336 - 34,544,149 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11334,455,154 - 34,544,147 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21337,676,725 - 37,757,893 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DNAH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12213,678,132 - 13,764,988 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2213,683,487 - 13,764,937 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041153,136,706 - 153,219,491 (-)NCBIVero_WHO_p1.0
Dnah1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248224,819,019 - 4,878,438 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248224,818,972 - 4,882,076 (-)NCBIHetGla_female_1.0hetGla2


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357403Slep4Serum leptin concentration QTL 43.91blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1619639137Rat
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16122477621Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
631561Hcuc2Hepatic copper content QTL 22.8hepatic copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)16285170915884239Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338015021361552Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
737825Alc13Alcohol consumption QTL 134.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760916039848Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
61372Bp40Blood pressure QTL 402.2blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)16422773017696785Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:168
Count of miRNA genes:76
Interacting mature miRNAs:84
Transcripts:ENSRNOT00000035009, ENSRNOT00000066508
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 8 1
Low 12 31 18 17 18 1 1 66 34 33 10 1
Below cutoff 1 28 24 21 2 21 7 10 8 1 7

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001033655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005494532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC095672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC099108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D26492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000035009   ⟹   ENSRNOP00000032434
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl166,456,002 - 6,518,350 (-)Ensembl
Rnor_6.0 Ensembl167,346,032 - 7,408,265 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000066508   ⟹   ENSRNOP00000059841
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl166,456,002 - 6,517,036 (-)Ensembl
Rnor_6.0 Ensembl167,345,978 - 7,406,951 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000113143   ⟹   ENSRNOP00000076750
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl166,456,002 - 6,518,350 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000114829   ⟹   ENSRNOP00000091035
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl166,456,002 - 6,517,036 (-)Ensembl
RefSeq Acc Id: NM_001033655   ⟹   NP_001028827
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,456,002 - 6,517,036 (-)NCBI
Rnor_6.0167,345,978 - 7,406,951 (-)NCBI
Rnor_5.0167,273,266 - 7,336,037 (-)NCBI
RGSC_v3.4166,693,763 - 6,754,535 (-)RGD
Celera168,672,026 - 8,733,031 (+)RGD
Sequence:
RefSeq Acc Id: XM_008770978   ⟹   XP_008769200
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,457,282 - 6,517,103 (-)NCBI
Rnor_6.0167,347,303 - 7,407,009 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599982   ⟹   XP_017455471
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,456,004 - 6,517,103 (-)NCBI
Rnor_6.0167,345,131 - 7,407,009 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599983   ⟹   XP_017455472
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,456,004 - 6,517,103 (-)NCBI
Rnor_6.0167,345,131 - 7,407,009 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599984   ⟹   XP_017455473
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,462,638 - 6,517,103 (-)NCBI
Rnor_6.0167,352,542 - 7,407,009 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039094181   ⟹   XP_038950109
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,455,514 - 6,513,185 (-)NCBI
RefSeq Acc Id: XM_039094182   ⟹   XP_038950110
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,456,004 - 6,517,103 (-)NCBI
RefSeq Acc Id: XM_039094184   ⟹   XP_038950112
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,456,004 - 6,517,103 (-)NCBI
RefSeq Acc Id: XM_039094185   ⟹   XP_038950113
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,456,004 - 6,509,646 (-)NCBI
RefSeq Acc Id: XM_039094186   ⟹   XP_038950114
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,456,004 - 6,497,232 (-)NCBI
RefSeq Acc Id: XR_005494532
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,469,164 - 6,517,103 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001028827   ⟸   NM_001033655
- UniProtKB: Q63164 (UniProtKB/Swiss-Prot),   D3ZRN8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008769200   ⟸   XM_008770978
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_017455472   ⟸   XM_017599983
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017455471   ⟸   XM_017599982
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017455473   ⟸   XM_017599984
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: ENSRNOP00000059841   ⟸   ENSRNOT00000066508
RefSeq Acc Id: ENSRNOP00000032434   ⟸   ENSRNOT00000035009
RefSeq Acc Id: XP_038950109   ⟸   XM_039094181
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038950110   ⟸   XM_039094182
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038950112   ⟸   XM_039094184
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038950113   ⟸   XM_039094185
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038950114   ⟸   XM_039094186
- Peptide Label: isoform X8
RefSeq Acc Id: ENSRNOP00000076750   ⟸   ENSRNOT00000113143
RefSeq Acc Id: ENSRNOP00000091035   ⟸   ENSRNOT00000114829
Protein Domains
AAA_6   AAA_8   AAA_9   AAA_lid_1   AAA_lid_11   DHC_N2   Dynein_AAA_lid   Dynein_C   Dynein_heavy   MT

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699931
Promoter ID:EPDNEW_R10454
Type:single initiation site
Name:Dnah1_1
Description:dynein, axonemal, heavy chain 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0167,406,976 - 7,407,036EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
16 7275729 7275730 T G snv SR/JrHsd (MCW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621795 AgrOrtholog
BioCyc Gene G2FUF-12153 BioCyc
Ensembl Genes ENSRNOG00000026914 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000032434 UniProtKB/Swiss-Prot
  ENSRNOP00000059841 ENTREZGENE
  ENSRNOP00000059841.3 UniProtKB/TrEMBL
  ENSRNOP00000076750 UniProtKB/Swiss-Prot
  ENSRNOP00000091035 ENTREZGENE
  ENSRNOP00000091035.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000035009 UniProtKB/Swiss-Prot
  ENSRNOT00000066508 ENTREZGENE
  ENSRNOT00000066508.5 UniProtKB/TrEMBL
  ENSRNOT00000113143 UniProtKB/Swiss-Prot
  ENSRNOT00000114829 ENTREZGENE
  ENSRNOT00000114829.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.710 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.8.720 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.140.100 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.10.490.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.20.180.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AAA_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_lid_11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_lid_11_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNAH3_AAA_lid_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_2_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_AAA1S UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_AAA5_ext UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_C_barrel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_HC_stalk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_heavy_chain_D4_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_heavy_D6_P-loop UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_heavy_dom-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:171339 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 171339 ENTREZGENE
Pfam AAA_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_lid_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_lid_11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DHC_N2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_AAA_lid UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_heavy UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF12777 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dnah1 PhenoGen
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6GJB4_RAT UniProtKB/TrEMBL
  D3ZRN8 ENTREZGENE, UniProtKB/TrEMBL
  DYH1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-17 Dnah1  dynein, axonemal, heavy chain 1  Dnahc1  dynein, axonemal, heavy chain 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-25 Dnahc1  dynein, axonemal, heavy chain 1  Dnah1  dynein, axonemal, heavy polypeptide 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-09-19 Dnah1  dynein, axonemal, heavy polypeptide 1  RGD1311110_predicted  similar to KIAA1410 protein (predicted)  Data Merged 737654 APPROVED
2005-01-20 Dnah1  dynein, axonemal, heavy polypeptide 1      Symbol and Name status set to approved 1299863 APPROVED
2005-01-20 RGD1311110_predicted  similar to KIAA1410 protein (predicted)  LOC306258_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC306258_predicted  similar to KIAA1410 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-08-07 Dnah1  dynein, axonemal, heavy polypeptide 1      Symbol and Name status set to provisional 70820 PROVISIONAL