Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Arr3 | Rat | Myopia 26, X-Linked, Female-Limited | | ISO | ARR3 (Homo sapiens) | 7240710 | | OMIM | | |
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Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Arr3 | Rat | Myopia 26, X-Linked, Female-Limited | | ISO | ARR3 (Homo sapiens) | 7240710 | | OMIM | | |
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# | Reference Title | Reference Citation |
1. | Photoreceptor signaling: supporting vision across a wide range of light intensities. | Arshavsky VY and Burns ME, J Biol Chem. 2012 Jan 13;287(3):1620-6. Epub 2011 Nov 10. |
2. | Identification of quantitative trait Loci for anxiety and locomotion phenotypes in rat recombinant inbred strains. | Conti LH, etal., Behav Genet 2004 Jan;34(1):93-103. |
3. | Cone arrestin identified by targeting expression of a functional family. | Craft CM, etal., J Biol Chem 1994 Feb 11;269(6):4613-9. |
4. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
5. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
6. | The functional cycle of visual arrestins in photoreceptor cells. | Gurevich VV, etal., Prog Retin Eye Res. 2011 Nov;30(6):405-30. Epub 2011 Jul 29. |
7. | Identification of a short linear sequence present in the C-terminal tail of the rat follitropin receptor that modulates arrestin-3 binding in a phosphorylation-independent fashion. | Kishi H, etal., J Biol Chem 2002 Jun 14;277(24):21939-46. |
8. | Loss of intracellular dystrophin: a potential mechanism for myocardial reperfusion injury. | Kyoi S, etal., Circ J. 2003 Aug;67(8):725-7. |
9. | Preferential Interaction between the dopamine D2 receptor and Arrestin2 in neostriatal neurons. | Macey TA, etal., Mol Pharmacol. 2004 Dec;66(6):1635-42. Epub 2004 Sep 10. |
10. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
11. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
12. | PID Annotation Import Pipeline | Pipeline to import Pathway Interaction Database annotations from NCI into RGD |
13. | GOA pipeline | RGD automated data pipeline |
14. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
PMID:10725384 | PMID:12486395 | PMID:15218143 | PMID:22159081 | PMID:23139825 | PMID:23704327 | PMID:25972452 | PMID:31080119 |
Arr3 (Rattus norvegicus - Norway rat) |
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ARR3 (Homo sapiens - human) |
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Arr3 (Mus musculus - house mouse) |
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Arr3 (Chinchilla lanigera - long-tailed chinchilla) |
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ARR3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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ARR3 (Canis lupus familiaris - dog) |
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Arr3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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ARR3 (Sus scrofa - pig) |
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ARR3 (Chlorocebus sabaeus - green monkey) |
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Arr3 (Heterocephalus glaber - naked mole-rat) |
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Variants in Arr3
20 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
AI233013 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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nervous system
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renal system
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reproductive system
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respiratory system
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9 | 11 | 33 | 51 | 49 | 48 | 17 | 25 | 17 | 6 | 126 | 81 | 31 | 11 | 22 | 31 |
Ensembl Acc Id: | ENSRNOT00000003946 ⟹ ENSRNOP00000003946 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000076264 | ||||||||
Type: | CODING | ||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000076671 ⟹ ENSRNOP00000068038 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000114787 ⟹ ENSRNOP00000087483 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001190993 ⟹ NP_001177922 | ||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039099437 ⟹ XP_038955365 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Protein RefSeqs | NP_001177922 | (Get FASTA) | NCBI Sequence Viewer |
XP_038955365 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAA17552 | (Get FASTA) | NCBI Sequence Viewer |
EDL95933 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000003946.4 | ||
ENSRNOP00000068038.2 | |||
ENSRNOP00000087483.1 | |||
GenBank Protein | P36576 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_001177922 ⟸ NM_001190993 |
- UniProtKB: | F1LMR6 (UniProtKB/TrEMBL), A6IQ79 (UniProtKB/TrEMBL) |
- Sequence: |
Ensembl Acc Id: | ENSRNOP00000003946 ⟸ ENSRNOT00000003946 |
Ensembl Acc Id: | ENSRNOP00000068038 ⟸ ENSRNOT00000076671 |
RefSeq Acc Id: | XP_038955365 ⟸ XM_039099437 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A6IQ79 (UniProtKB/TrEMBL) |
Ensembl Acc Id: | ENSRNOP00000087483 ⟸ ENSRNOT00000114787 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-P36576-F1-model_v2 | AlphaFold | P36576 | 1-92 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
Database | Acc Id | Source(s) |
AGR Gene | RGD:621385 | AgrOrtholog |
BioCyc Gene | G2FUF-2129 | BioCyc |
Ensembl Genes | ENSRNOG00000002904 | Ensembl, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000003946.5 | UniProtKB/TrEMBL |
ENSRNOT00000076671.3 | UniProtKB/TrEMBL | |
ENSRNOT00000114787.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 2.60.40.640 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
2.60.40.840 | UniProtKB/TrEMBL | |
InterPro | Arrestin | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Arrestin-like_C | UniProtKB/TrEMBL | |
Arrestin-like_N | UniProtKB/TrEMBL | |
Arrestin_C | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Arrestin_CS | UniProtKB/TrEMBL | |
Arrestin_N | UniProtKB/TrEMBL | |
Ig_E-set | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:171107 | UniProtKB/TrEMBL |
NCBI Gene | 171107 | ENTREZGENE |
PANTHER | PTHR11792 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PTHR11792:SF19 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | Arrestin_C | UniProtKB/TrEMBL |
Arrestin_N | UniProtKB/TrEMBL | |
PhenoGen | Arr3 | PhenoGen |
PRINTS | ARRESTIN | UniProtKB/TrEMBL |
PROSITE | ARRESTINS | UniProtKB/TrEMBL |
RatGTEx | ENSRNOG00000002904 | RatGTEx |
SMART | Arrestin_C | UniProtKB/TrEMBL |
Superfamily-SCOP | SSF81296 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
UniProt | A0A096MJ89_RAT | UniProtKB/TrEMBL |
A0A8I6A8Q4_RAT | UniProtKB/TrEMBL | |
A6IQ79 | ENTREZGENE, UniProtKB/TrEMBL | |
ARRC_RAT | UniProtKB/Swiss-Prot | |
F1LMR6 | ENTREZGENE, UniProtKB/TrEMBL | |
P36576 | ENTREZGENE |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2016-07-21 | Arr3 | arrestin 3 | Arr3 | arrestin 3, retinal (X-arrestin) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-09-25 | Arr3 | arrestin 3, retinal (X-arrestin) | Arr3 | arrestin 3, retinal | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2005-01-20 | Arr3 | arrestin 3, retinal | arrestin 3, retinal (X-arrestin) | Name updated | 1299863 | APPROVED | |
2002-08-07 | Arr3 | arrestin 3, retinal (X-arrestin) | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
Note Type | Note | Reference |
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gene_disease | human homolog located at X chromosome, may be candidate for several inherited X-linked retinopathies | 727257 |
gene_expression | present in the retina with cone photoreceptors and in the pineal to a subpopulation of pinealocytes | 727257 |
gene_function | binds to cone-related G-protein-coupled receptors | 727257 |