Arr3 (arrestin 3) - Rat Genome Database
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Gene: Arr3 (arrestin 3) Rattus norvegicus
Analyze
Symbol: Arr3
Name: arrestin 3
RGD ID: 621385
Description: Exhibits protein domain specific binding activity. Involved in visual perception. Predicted to localize to photoreceptor inner segment; photoreceptor outer segment; and synapse. Human ortholog(s) of this gene implicated in myopia. Orthologous to human ARR3 (arrestin 3); PARTICIPATES IN eicosanoid signaling pathway; visual phototransduction pathway; INTERACTS WITH ammonium chloride; bisphenol A; copper atom.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: arrestin 3, retinal; arrestin 3, retinal (X-arrestin); arrestin-C; cArr; cone arrestin; retinal cone arrestin-3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X65,699,881 - 65,712,224 (+)NCBI
Rnor_6.0 EnsemblX70,438,617 - 70,452,067 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X70,438,590 - 70,452,140 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X71,310,209 - 71,323,756 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X88,602,380 - 88,614,721 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X88,684,283 - 88,688,153 (+)NCBI
CeleraX66,058,741 - 66,071,082 (+)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:10725384   PMID:12486395   PMID:15218143   PMID:22159081   PMID:23139825   PMID:23704327   PMID:25972452   PMID:31080119  


Genomics

Comparative Map Data
Arr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X65,699,881 - 65,712,224 (+)NCBI
Rnor_6.0 EnsemblX70,438,617 - 70,452,067 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X70,438,590 - 70,452,140 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X71,310,209 - 71,323,756 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X88,602,380 - 88,614,721 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X88,684,283 - 88,688,153 (+)NCBI
CeleraX66,058,741 - 66,071,082 (+)NCBICelera
Cytogenetic MapXq22NCBI
ARR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX70,268,305 - 70,281,840 (+)EnsemblGRCh38hg38GRCh38
GRCh38X70,268,334 - 70,281,840 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X69,488,184 - 69,501,690 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh37X69,488,185 - 69,501,691 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X69,404,910 - 69,418,415 (+)NCBINCBI36hg18NCBI36
Build 34X69,271,222 - 69,284,711NCBI
CeleraX69,841,522 - 69,855,024 (+)NCBI
Cytogenetic MapXq13.1NCBI
HuRefX63,309,253 - 63,322,604 (+)NCBIHuRef
CHM1_1X69,382,163 - 69,395,648 (+)NCBICHM1_1
Arr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X99,649,086 - 99,662,099 (+)NCBIGRCm39mm39
GRCm38X100,605,480 - 100,618,493 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX100,605,497 - 100,618,493 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X97,800,836 - 97,813,832 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X96,808,275 - 96,821,212 (+)NCBImm8
CeleraX87,531,523 - 87,544,518 (+)NCBICelera
Cytogenetic MapXC3NCBI
Arr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554759,819,792 - 9,835,200 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554759,819,783 - 9,835,526 (+)NCBIChiLan1.0ChiLan1.0
ARR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X69,596,163 - 69,609,624 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX69,596,163 - 69,609,624 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X59,536,796 - 59,550,274 (+)NCBIMhudiblu_PPA_v0panPan3
ARR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 EnsemblX54,718,323 - 54,730,852 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1X54,725,034 - 54,730,920 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Arr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049367621,194,251 - 1,207,914 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX56,296,596 - 56,310,504 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X56,295,107 - 56,310,507 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X63,491,381 - 63,505,290 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARR3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X60,111,875 - 60,127,144 (+)NCBI
ChlSab1.1 EnsemblX60,114,643 - 60,127,255 (+)Ensembl
Arr3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624903246,888 - 255,169 (+)NCBI

Position Markers
AI233013  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X70,444,149 - 70,444,256NCBIRnor6.0
Rnor_5.0X71,315,767 - 71,315,874UniSTSRnor5.0
RGSC_v3.4X88,606,732 - 88,606,839UniSTSRGSC3.4
CeleraX66,063,093 - 66,063,200UniSTS
Cytogenetic MapXq31UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X15688119127888215Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X44320616158345622Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX44557974120045269Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X70352120127888215Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:32
Count of miRNA genes:31
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000003946
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2
Low 3 11 25 9 19 9 8 9 15 11 7 11 8
Below cutoff 16 2 2 2 2 2 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000003946   ⟹   ENSRNOP00000003946
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX70,440,059 - 70,452,038 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076264
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX70,445,516 - 70,446,687 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076671   ⟹   ENSRNOP00000068038
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX70,438,617 - 70,452,067 (+)Ensembl
RefSeq Acc Id: NM_001190993   ⟹   NP_001177922
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X65,699,881 - 65,712,224 (+)NCBI
Rnor_6.0X70,439,797 - 70,452,138 (+)NCBI
Rnor_5.0X71,310,209 - 71,323,756 (+)NCBI
CeleraX66,058,741 - 66,071,082 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006257053   ⟹   XP_006257115
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X70,438,590 - 70,452,140 (+)NCBI
Rnor_5.0X71,310,209 - 71,323,756 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601901   ⟹   XP_017457390
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X70,438,590 - 70,451,100 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601902   ⟹   XP_017457391
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X70,440,305 - 70,451,100 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039099437   ⟹   XP_038955365
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X65,701,878 - 65,712,224 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001177922 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955365 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA17552 (Get FASTA)   NCBI Sequence Viewer  
  EDL95933 (Get FASTA)   NCBI Sequence Viewer  
  P36576 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001177922   ⟸   NM_001190993
- UniProtKB: A0A096MJ89 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257115   ⟸   XM_006257053
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017457390   ⟸   XM_017601901
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017457391   ⟸   XM_017601902
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000003946   ⟸   ENSRNOT00000003946
RefSeq Acc Id: ENSRNOP00000068038   ⟸   ENSRNOT00000076671
RefSeq Acc Id: XP_038955365   ⟸   XM_039099437
- Peptide Label: isoform X1
Protein Domains
Arrestin_C

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621385 AgrOrtholog
Ensembl Genes ENSRNOG00000002904 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000003946 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000068038 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003946 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000076671 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.640 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.840 UniProtKB/TrEMBL
InterPro ARR3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin-like_C UniProtKB/TrEMBL
  Arrestin-like_N UniProtKB/TrEMBL
  Arrestin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin_CS UniProtKB/TrEMBL
  Arrestin_N UniProtKB/TrEMBL
  Ig_E-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:171107 UniProtKB/TrEMBL
NCBI Gene 171107 ENTREZGENE
PANTHER PTHR11792 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11792:SF19 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Arrestin_C UniProtKB/TrEMBL
  Arrestin_N UniProtKB/TrEMBL
PhenoGen Arr3 PhenoGen
PRINTS ARRESTIN UniProtKB/TrEMBL
PROSITE ARRESTINS UniProtKB/TrEMBL
SMART Arrestin_C UniProtKB/TrEMBL
Superfamily-SCOP SSF81296 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A096MJ89 ENTREZGENE, UniProtKB/TrEMBL
  ARRC_RAT UniProtKB/Swiss-Prot
  F1LMR6_RAT UniProtKB/TrEMBL
  P36576 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-21 Arr3  arrestin 3  Arr3  arrestin 3, retinal (X-arrestin)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Arr3  arrestin 3, retinal (X-arrestin)  Arr3  arrestin 3, retinal  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Arr3  arrestin 3, retinal    arrestin 3, retinal (X-arrestin)  Name updated 1299863 APPROVED
2002-08-07 Arr3  arrestin 3, retinal (X-arrestin)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_disease human homolog located at X chromosome, may be candidate for several inherited X-linked retinopathies 727257
gene_expression present in the retina with cone photoreceptors and in the pineal to a subpopulation of pinealocytes 727257
gene_function binds to cone-related G-protein-coupled receptors 727257