Tex101 (testis expressed 101) - Rat Genome Database

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Pathways
Gene: Tex101 (testis expressed 101) Rattus norvegicus
Analyze
Symbol: Tex101
Name: testis expressed 101
RGD ID: 621373
Description: Involved in basophil activation and regulation of cytosolic calcium ion concentration. Located in cell surface. Orthologous to human TEX101 (testis expressed 101); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-Tetrachlorodibenzofuran; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: lipid raft-associated glycoprotein TEC-21; LOC100911185; Tec21; testis expressed gene 101; testis-expressed protein 101; testis-expressed sequence 101 protein; testis-expressed sequence 101 protein-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8189,382,974 - 89,387,340 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl189,382,974 - 89,387,340 (-)EnsemblGRCr8
mRatBN7.2180,255,076 - 80,259,442 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl180,255,076 - 80,259,442 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx185,646,992 - 85,651,359 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0194,198,491 - 94,202,857 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0187,402,749 - 87,407,116 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0181,529,776 - 81,534,149 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl181,529,781 - 81,534,140 (-)Ensemblrn6Rnor6.0
Rnor_5.0182,787,105 - 82,791,476 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4179,946,338 - 79,949,053 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera174,707,230 - 74,709,945 (-)NCBICelera
RGSC_v3.1180,024,449 - 80,027,164 (-)NCBI
Cytogenetic Map1q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. New monoclonal antibodies to rat testicular antigen, TEC-21. Halova I, etal., Folia Biol (Praha) 2001;47(5):180-2.
3. A novel lipid raft-associated glycoprotein, TEC-21, activates rat basophilic leukemia cells independently of the type 1 Fc epsilon receptor. Halova I, etal., Int Immunol 2002 Feb;14(2):213-23.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16822331   PMID:18503752   PMID:18620756   PMID:19144954   PMID:21724266   PMID:23633567   PMID:23969891   PMID:27005865  


Genomics

Comparative Map Data
Tex101
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8189,382,974 - 89,387,340 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl189,382,974 - 89,387,340 (-)EnsemblGRCr8
mRatBN7.2180,255,076 - 80,259,442 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl180,255,076 - 80,259,442 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx185,646,992 - 85,651,359 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0194,198,491 - 94,202,857 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0187,402,749 - 87,407,116 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0181,529,776 - 81,534,149 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl181,529,781 - 81,534,140 (-)Ensemblrn6Rnor6.0
Rnor_5.0182,787,105 - 82,791,476 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4179,946,338 - 79,949,053 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera174,707,230 - 74,709,945 (-)NCBICelera
RGSC_v3.1180,024,449 - 80,027,164 (-)NCBI
Cytogenetic Map1q21NCBI
TEX101
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381943,388,611 - 43,418,597 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1943,401,496 - 43,418,597 (+)Ensemblhg38GRCh38
GRCh371943,892,763 - 43,922,749 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361948,584,603 - 48,614,589 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341948,584,602 - 48,614,588NCBI
Celera1940,693,597 - 40,723,504 (+)NCBICelera
Cytogenetic Map19q13.31NCBI
HuRef1940,322,583 - 40,352,669 (+)NCBIHuRef
CHM1_11943,894,311 - 43,924,421 (+)NCBICHM1_1
T2T-CHM13v2.01946,209,044 - 46,238,972 (+)NCBIT2T-CHM13v2.0
Tex101
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39724,367,437 - 24,371,475 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl724,367,432 - 24,376,100 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38724,668,012 - 24,672,050 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl724,668,007 - 24,676,675 (-)Ensemblmm10GRCm38
MGSCv37725,453,031 - 25,457,069 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36724,376,772 - 24,380,810 (-)NCBIMGSCv36mm8
Celera719,281,919 - 19,285,957 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map712.13NCBI
Tex101
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555551,138,100 - 1,140,882 (+)Ensembl
ChiLan1.0NW_0049555551,136,499 - 1,140,802 (+)NCBIChiLan1.0ChiLan1.0
TEX101
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22049,570,415 - 49,576,561 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11951,439,476 - 51,445,453 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01940,356,333 - 40,359,285 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11948,943,130 - 48,969,317 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1948,947,871 - 48,969,317 (+)EnsemblpanPan2panpan1.1
TEX101
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11111,683,964 - 111,687,115 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1111,683,961 - 111,687,179 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1111,163,495 - 111,166,646 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01112,293,938 - 112,297,089 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1112,294,110 - 112,296,308 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11111,882,014 - 111,885,165 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01111,515,794 - 111,518,945 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01112,400,228 - 112,403,378 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tex101
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934916,300,884 - 16,304,512 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936706649,463 - 690,995 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TEX101
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl650,269,989 - 50,275,028 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1650,271,730 - 50,274,745 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2646,130,992 - 46,134,079 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TEX101
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1636,901,050 - 36,934,310 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607316,468,172 - 16,471,029 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tex101
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624907979,778 - 981,959 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624907978,395 - 983,659 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Tex101
8 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:165
Count of miRNA genes:135
Interacting mature miRNAs:147
Transcripts:ENSRNOT00000027202
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)18126986099645535Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)184107164115183752Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat

Markers in Region
RH132043  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2180,255,228 - 80,255,415 (+)MAPPERmRatBN7.2
Rnor_6.0181,529,929 - 81,530,115NCBIRnor6.0
Rnor_5.0182,787,258 - 82,787,444UniSTSRnor5.0
RGSC_v3.4179,946,486 - 79,946,672UniSTSRGSC3.4
Celera174,707,378 - 74,707,564UniSTS
RH 3.4 Map1823.5UniSTS
Cytogenetic Map1q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 4 14 79 53 57 37 48 37 159 73 10 69 37 83 20 3 3

Sequence


Ensembl Acc Id: ENSRNOT00000027202   ⟹   ENSRNOP00000027202
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl189,382,974 - 89,387,340 (-)Ensembl
mRatBN7.2 Ensembl180,255,076 - 80,259,442 (-)Ensembl
Rnor_6.0 Ensembl181,529,781 - 81,534,140 (-)Ensembl
RefSeq Acc Id: NM_139037   ⟹   NP_620606
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8189,382,974 - 89,387,340 (-)NCBI
mRatBN7.2180,255,076 - 80,259,442 (-)NCBI
Rnor_6.0181,529,781 - 81,532,496 (-)NCBI
Rnor_5.0182,787,105 - 82,791,476 (-)NCBI
RGSC_v3.4179,946,338 - 79,949,053 (-)RGD
Celera174,707,230 - 74,709,945 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_620606 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAK58911 (Get FASTA)   NCBI Sequence Viewer  
  EDM08077 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000027202
GenBank Protein Q924B5 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_620606   ⟸   NM_139037
- Peptide Label: precursor
- UniProtKB: Q924B5 (UniProtKB/Swiss-Prot),   G3V8N9 (UniProtKB/TrEMBL),   A6J907 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000027202   ⟸   ENSRNOT00000027202
Protein Domains
UPAR/Ly6

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q924B5-F1-model_v2 AlphaFold Q924B5 1-250 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689804
Promoter ID:EPDNEW_R328
Type:initiation region
Name:Tex101_1
Description:testis expressed 101
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0181,534,130 - 81,534,190EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621373 AgrOrtholog
BioCyc Gene G2FUF-60433 BioCyc
Ensembl Genes ENSRNOG00000020057 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000027202 ENTREZGENE
InterPro Fert-Immune_med_protein UniProtKB/Swiss-Prot
  LY6_UPA_recep-like UniProtKB/Swiss-Prot
KEGG Report rno:207113 UniProtKB/Swiss-Prot
NCBI Gene 207113 ENTREZGENE
PANTHER CD177 ANTIGEN UniProtKB/Swiss-Prot
  CD177 ANTIGEN UniProtKB/Swiss-Prot
Pfam UPAR_LY6 UniProtKB/Swiss-Prot
PhenoGen Tex101 PhenoGen
RatGTEx ENSRNOG00000020057 RatGTEx
UniProt A6J907 ENTREZGENE, UniProtKB/TrEMBL
  G3V8N9 ENTREZGENE, UniProtKB/TrEMBL
  Q924B5 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Tex101  testis expressed 101  LOC100911185  testis-expressed sequence 101 protein-like  Data merged from RGD:6494867 737654 PROVISIONAL
2012-07-05 LOC100911185  testis-expressed sequence 101 protein-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-09-24 Tex101  testis expressed 101  Tex101  testis expressed gene 101  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Tex101  testis expressed gene 101  Tec21  lipid raft-associated glycoprotein TEC-21  Symbol and Name updated 1299863 APPROVED
2002-08-07 Tec21  lipid raft-associated glycoprotein TEC-21      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to lipid rafts on plasma membrane 634491
gene_protein glycosylphosphatidylinositol-anchored plasma membrane glycoprotein 634491