Ttl (tubulin tyrosine ligase) - Rat Genome Database

Name: Ttl
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes Projects (beta) QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: Ttl (tubulin tyrosine ligase) Rattus norvegicus

Analyze

Symbol:

Ttl

Name:

tubulin tyrosine ligase

RGD ID:

621113

Description:

Enables tubulin-tyrosine ligase activity. Predicted to be involved in several processes, including positive regulation of mitotic cell cycle; post-translational protein modification; and regulation of metaphase plate congression. Predicted to act upstream of or within regulation of axon extension. Predicted to be active in spindle microtubule. Orthologous to human TTL (tubulin tyrosine ligase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

tubulin--tyrosine ligase

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TTL (tubulin tyrosine ligase)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Ttl (tubulin tyrosine ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ttl (tubulin tyrosine ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TTL (tubulin tyrosine ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TTL (tubulin tyrosine ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ttl (tubulin tyrosine ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TTL (tubulin tyrosine ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TTL (tubulin tyrosine ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ttl (tubulin tyrosine ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	TTL (tubulin tyrosine ligase)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ttl (tubulin tyrosine ligase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ttl (tubulin tyrosine ligase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ttl	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	116,298,813 - 116,328,538 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	116,298,797 - 116,328,538 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	120,196,066 - 120,222,520 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	128,791,655 - 128,818,105 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	126,452,127 - 126,478,585 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	121,596,773 - 121,626,581 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	121,596,791 - 121,624,048 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	128,388,189 - 128,417,974 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	116,671,419 - 116,697,989 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	116,576,991 - 116,603,562 (+)	NCBI
Celera	3	115,124,248 - 115,150,813 (+)	NCBI		Celera
Cytogenetic Map	3	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,4-methylenedioxymethamphetamine (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP,ISO)

bortezomib (ISO)

cadmium dichloride (EXP)

chrysene (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

diazinon (ISO)

doxorubicin (ISO)

epoxiconazole (ISO)

ethanol (ISO)

genistein (ISO)

gentamycin (EXP)

indole-3-methanol (EXP)

lead(0) (ISO)

methotrexate (ISO)

N-nitrosodiethylamine (EXP)

paracetamol (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorononanoic acid (ISO)

perfluorooctanoic acid (ISO)

PhIP (ISO)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

rotenone (ISO)

tetraphene (ISO)

thioacetamide (EXP)

tributylstannane (EXP)

trichloroethene (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

microtubule cytoskeleton organization (IBA,IEA,ISO)

positive regulation of mitotic cell cycle (IEA,ISO)

post-translational protein modification (IEA,ISO)

protein modification process (IEA)

regulation of axon extension (IEA,ISO)

regulation of metaphase plate congression (IEA,ISO)

Cellular Component

spindle microtubule (IBA,IEA,ISO)

Molecular Function

acid-amino acid ligase activity (IEA)

ATP binding (IEA)

catalytic activity, acting on a protein (IEA)

tubulin-tyrosine ligase activity (IBA,IDA,IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Tubulin tyrosine ligase: protein and mRNA expression in developing rat skeletal muscle.	Arregui CO, etal., Dev Growth Differ 1997 Apr;39(2):167-78.
2.	Characterization of the tubulin-tyrosine ligase.	Ersfeld K, etal., J Cell Biol 1993 Feb;120(3):725-32.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	GOA pipeline	RGD automated data pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12512949	PMID:15899979	PMID:25908662

Genomics

Comparative Map Data

Ttl
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	116,298,813 - 116,328,538 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	116,298,797 - 116,328,538 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	120,196,066 - 120,222,520 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	128,791,655 - 128,818,105 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	126,452,127 - 126,478,585 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	121,596,773 - 121,626,581 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	121,596,791 - 121,624,048 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	128,388,189 - 128,417,974 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	116,671,419 - 116,697,989 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	116,576,991 - 116,603,562 (+)	NCBI
Celera	3	115,124,248 - 115,150,813 (+)	NCBI		Celera
Cytogenetic Map	3	q36	NCBI

TTL
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	112,482,156 - 112,541,739 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	112,482,156 - 112,541,739 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	113,239,733 - 113,299,316 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	112,956,214 - 113,006,694 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	112,956,128 - 113,006,212	NCBI
Celera	2	106,625,279 - 106,675,764 (+)	NCBI		Celera
Cytogenetic Map	2	q14.1	NCBI
HuRef	2	105,693,725 - 105,744,724 (+)	NCBI		HuRef
CHM1_1	2	113,243,890 - 113,294,368 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	112,908,795 - 112,968,389 (+)	NCBI		T2T-CHM13v2.0

Ttl
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	128,907,867 - 128,938,203 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	128,907,862 - 128,938,203 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	129,065,947 - 129,096,283 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	129,065,942 - 129,096,283 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	128,891,683 - 128,922,019 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	128,757,430 - 128,785,190 (+)	NCBI		MGSCv36	mm8
Celera	2	130,293,491 - 130,323,607 (+)	NCBI		Celera
Cytogenetic Map	2	F1	NCBI
cM Map	2	62.65	NCBI

Ttl
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955470	1,743,751 - 1,774,512 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955470	1,747,217 - 1,774,512 (-)	NCBI	ChiLan1.0	ChiLan1.0

TTL
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	2A	15,594,017 - 15,635,068 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	89,526,022 - 89,567,068 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	113,505,416 - 113,546,896 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	113,505,416 - 113,546,896 (+)	Ensembl	panpan1.1		panPan2

TTL
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	36,735,836 - 36,770,292 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	36,735,788 - 36,767,016 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	36,504,890 - 36,539,300 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	37,511,436 - 37,545,848 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	37,511,409 - 37,545,835 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	36,649,169 - 36,683,745 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	36,703,448 - 36,738,023 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	36,917,312 - 36,951,900 (+)	NCBI		UU_Cfam_GSD_1.0

Ttl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	82,096,219 - 82,130,048 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936783	989,269 - 1,025,690 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936783	989,269 - 1,024,537 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TTL
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	43,977,265 - 44,022,635 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	43,980,634 - 44,022,611 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	45,574,533 - 45,617,612 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TTL
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	15,500,417 - 15,540,252 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	15,500,520 - 15,538,184 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666080	4,140,168 - 4,186,856 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ttl
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624749	12,549,969 - 12,595,490 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624749	12,550,017 - 12,595,397 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ttl
152 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	53
Count of miRNA genes:	46
Interacting mature miRNAs:	51
Transcripts:	ENSRNOT00000024694
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	29463235	118376539	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	38192233	133483320	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	43827364	121056321	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	47233211	147415807	Rat
631665	Bw8	Body weight QTL 8	5.5		body mass (VT:0001259)	body weight (CMO:0000012)	3	50437042	119183768	Rat
1581568	Rf53	Renal function QTL 53			urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	56395968	161299569	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	59242096	157323038	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	61017749	121056321	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	70348525	121056321	Rat
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	70653097	121056321	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	73376539	118376539	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	78196190	146592722	Rat
631649	Bp123	Blood pressure QTL 123	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	89772419	134772419	Rat
8694437	Bw167	Body weight QTL 167	22.46	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	3	91797474	136797474	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	94856903	159898684	Rat
724532	Cm17	Cardiac mass QTL 17	2		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	3	95735366	140735366	Rat
1354611	Despr2	Despair related QTL 2	3.03	0.0028	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	3	97084464	142084464	Rat
2293087	Iddm27	Insulin dependent diabetes mellitus QTL 27	2.68		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	97551417	147415807	Rat
2312659	Slep7	Serum leptin concentration QTL 7		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	3	98535255	168026850	Rat
2312670	Bw94	Body weight QTL 94		0.01	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	3	98535255	168026850	Rat
2312673	Scl63	Serum cholesterol level QTL 63		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	98535255	168026850	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	98535386	161695835	Rat
619618	Rf3	Renal disease susceptibility QTL 3	6.5	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate to body weight ratio (CMO:0001270)	3	107693393	152693393	Rat
1331758	Bp207	Blood pressure QTL 207	2.848		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	112287552	135181505	Rat
1578754	Stresp16	Stress response QTL 16	4	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	3	112681431	157681431	Rat
1358204	Insglur1	Insulin/glucose ratio QTL 1	3.8		blood glucose amount (VT:0000188)	serum insulin level (CMO:0000358)	3	115638168	135181505	Rat
1358204	Insglur1	Insulin/glucose ratio QTL 1	3.8		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	3	115638168	135181505	Rat

Markers in Region

D3Uwm5

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	116,307,136 - 116,307,352 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	121,605,101 - 121,605,316	NCBI	Rnor6.0
Rnor_5.0	3	128,409,454 - 128,409,669	UniSTS	Rnor5.0
RGSC_v3.4	3	116,679,701 - 116,679,917	RGD	RGSC3.4
RGSC_v3.4	3	116,679,702 - 116,679,917	UniSTS	RGSC3.4
RGSC_v3.1	3	116,585,274 - 116,585,490	RGD
Celera	3	115,132,531 - 115,132,747	UniSTS
Cytogenetic Map	3	q36	UniSTS

RH133188

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	116,325,728 - 116,325,904 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	121,623,772 - 121,623,947	NCBI	Rnor6.0
Rnor_5.0	3	128,390,823 - 128,390,998	UniSTS	Rnor5.0
RGSC_v3.4	3	116,698,294 - 116,698,469	UniSTS	RGSC3.4
Celera	3	115,151,118 - 115,151,293	UniSTS
RH 3.4 Map	3	997.3	UniSTS
Cytogenetic Map	3	q36	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	1	39	21	6	14	6	8	11	74	24	39	11	8
Low	2	4	36	35	5	35				11	2
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_138536	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234946	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104213	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005501768	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF207605	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000118	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U53214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000024694 ⟹ ENSRNOP00000024695

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	116,298,835 - 116,328,538 (+)	Ensembl
Rnor_6.0 Ensembl	3	121,596,791 - 121,624,048 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000109318 ⟹ ENSRNOP00000090593

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	116,298,797 - 116,328,538 (+)	Ensembl

RefSeq Acc Id:

NM_138536 ⟹ NP_612545

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	116,298,854 - 116,325,424 (+)	NCBI
Rnor_6.0	3	121,596,818 - 121,623,467 (+)	NCBI
Rnor_5.0	3	128,388,189 - 128,417,974 (-)	NCBI
RGSC_v3.4	3	116,671,419 - 116,697,989 (+)	RGD
Celera	3	115,124,248 - 115,150,813 (+)	RGD

Sequence:

show sequence

CCAGGGCAGACACTAGATAATCCGGAGCGCGGCCCTGGAATTGGGCAGACAGCGGGACTGAGAC
TGAAGCTGGGGCAGTGAGCACGCGGAGACCGCCGTCCCTTGGACTACGGCTTGTGGCGGCTGCG
GGGCGCGCTGCCCTTCGCCATGTACACCTTCGTGGTGCGCCAGGAGAATAGCAGCGTCTACGCC
GAGGTCTCCCGGCTGCTGCTGGCCACCGGCTACTGGAAGAGGCTGCGGCGGGACAACCCCAGGT
TCAACCTGATGCTGGGCGGAAGGAACCGACTGCCTTTCGGGAGACTAGGACACGAACCTGGGCT
GGCACAGCTGGTGAACTACTACAGGGGGGCCGACAAACTGTGCCGCAAAGCTTCCTTAGTGAAG
CTAGTCAAGACCAGTCCGGAACTGTCTGAGTCCTGCTCATGGTTCCCCGAGTCCTATGTGATTC
ATCCAACTAACCTCAAGACGCCAGTCGCTCCAGCGCAGAATGGCATCCAGCTTCCGGTCAGTAA
CTCCAGGACAGATGAGAGAGAATTCTTCTTGGCTTCTTATAACAGAAAGAAAGAGGACGGGGAA
GGCAACGTTTGGATTGCAAAGTCATCAGCTGGTGCCAAAGGCGAAGGCATCCTCATCTCCTCAG
AGGCGTCAGAGCTTCTGGATTTTATAGACAACCAGGGCCAAGTGCACGTGATCCAGAAATACCT
CGAGCACCCTCTGCTCCTCGAGCCCGGTCACCGCAAGTTTGACATTCGAAGCTGGGTCCTGGTT
GACCACCAGTATAACATCTACCTCTACAGAGAGGGTGTGCTTCGAACTGCTTCAGAACCATATC
ATGTTGATAACTTCCAAGATAAGACCTGCCATCTGACCAATCACTGCATTCAGAAAGAGTACTC
AAAGAACTATGGAAAATACGAAGAAGGGAACGAAATGTTCTTCGAAGAGTTCAATCAGTACCTA
ACAAGCGCTCTGAACATTACCCTAGAAAATAGCATCTTGCTGCAAATCAAACACATAATAAGGA
GCTGCCTCATGAGCGTGGAGCCCGCCATCAGCACCAAGCACCTCCCTTACCAGAGCTTCCAGCT
CCTTGGCTTTGACTTCATGGTGGATGAGGAGCTGAAAGTCTGGCTCATTGAGGTCAACGGTGCC
CCTGCGTGTGCCCAGAAGCTCTATGCAGAACTGTGTCAGGGCATCGTGGACATAGCCATATCCA
GCGTCTTCCCACCCCCAGACACGGAGCAGGTGCCGCAGCAGCCGGCTGCTTTCATGAAGCTGTG
AAGGACTGGAAGGCACAGAGCCACCTTGGGAAATGTATGGGGTCTGCTCCAGAGGAACGTGAGA
TGGCTGGACTGCTCCTGACCAAGGCATCTGGGGAACCAGATGTCAGGAA

hide sequence

RefSeq Acc Id:

XM_006234946 ⟹ XP_006235008

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	116,298,813 - 116,328,538 (+)	NCBI
Rnor_6.0	3	121,596,773 - 121,626,581 (+)	NCBI
Rnor_5.0	3	128,388,189 - 128,417,974 (-)	NCBI

Sequence:

show sequence

GCGGCGTCCGGGTGGCGCTCGCCACTCGGGCGGTGGCGCGGGCGCCCAGGGCAGACACCAGGAT
AATCCGGAGGCGCGGCCCTGGAATTGGGCAGACAGCGGGACTGAGACTGAAGCTGGGGCAGTGA
GCACGCGGAGCCGCCGTCCCTTGGACTACGGCTTGTGGCGGCTGCGGGGCGCGCTGCCCTTCGC
CATGTACACCTTCGTGGTGCGCGACGAGAATAGCAGCGTCTACGCCGAGGTCTCCCGGCTGCTG
CTGGCCACCGGCTACTGGAAGAGGCTGCGGCGGGACAACCCCAGGTTCAACCTGATGCTGGGCG
AGAGGAACCGACTGCCTTTCGGGAGACTAGGTCACGAACCTGGGCTGGCACAGCTGGTGAACTA
CTACAGGGGGGCGGACAAACTGTGCCGCAAAGCTTCCTTAGTGAAGCTAGTCAAGACCAGTCCG
GAACTGTCTGAGTCCTGCTCATGGTTCCCCGAGTCCTATGTGATTTATCCAACTAACCTCAAGA
CGCCAGTCGCTCCAGCGCAGAATGGCATCCAGCTTCCGGTCAGTAACTCCAGGACAGATGAGAG
AGAATTCTTCTTGGCTTCTTATAACAGAAAGAAAGAGGACGGGGAAGGCAACGTTTGGATTGCA
AAGTCATCAGCTGGTGCCAAAGGCGAAGGCATCCTCATCTCCTCAGAGGCGTCAGAGCTTCTGG
ATTTTATAGACAACCAGGGCCAAGTGCACGTGATCCAGAAATACCTCGAGCACCCTCTGCTCCT
CGAGCCCGGTCACCGCAAGTTTGACATTCGAGAGGGTGTGCTTCGAACTGCTTCAGAACCATAT
CATGTTGATAACTTCCAAGATAAGACCTGCCATCTGACCAATCACTGCATTCAGAAAGAGTACT
CAAAGAACTATGGGAAATACGAAGAAGGGAACGAAATGTTCTTCGAAGAGTTCAATCAGTACCT
AACAAGCGCTCTGAACATTACCCTAGAAAATAGCATCTTGCTGCAAATCAAACACATAATAAGG
AGCTGCCTCATGAGCGTGGAGCCCGCCATCAGCACCAAGCACCTCCCTTACCAGAGCTTCCAGC
TCCTTGGCTTTGACTTCATGGTGGATGAGGAGCTGAAAGTCTGGCTCATTGAGGTCAACGGTGC
CCCTGCGTGTGCCCAGAAGCTCTATGCAGAACTGTGTCAGGGCATCGTGGACATAGCCATATCC
AGCGTCTTCCCACCCCCAGACACGGAGCAGGTGCCGCAGCAGCCGGCTGCGTTCATGAAGCTGT
GAAGGACTGGAAGGCACAGAGCCACCTTGGGAAATGTATGGGGTCCTGCTCCAGAGGAACGTGA
GATGGCTGGACTGCTCCTGACCAAGGCATGCTGGGGAACAGATGTGCAGGAAGAACAGAAGAGC
AGCCGGGCTGCCCACAGTGCTGTGGAGACCTTAGGAAGCTGACAGAAGTAACTGAGAGGGAGAG
CCAGACGCTTTTCTAAAAGGCTGGAACCAGGGATTTGTTATGGTGCGATCTGATCCCTTGAGCG
GTTTCTGGTCTTGGGTGGTTCTGGGAACAGCTCCTCCTCCCTGGGATGCAGCTCGGGGCCTCTG
AGGGGTGTCTCCCCACCTGCTGCAGCTTTAGTGCCTTAGTCTGTGCCCGGTGCAGCCTCACTGG
ACACAGACTGGACCTTAGAGCATTTTAGAGGTTGCCACATGTTCCCTGCACATTCCTTCCGTGA
TGCTGTCCTGCCGAACTCTGGACAAGCATAGAGCACAGTCCATGCTGCGCCCTGGCCTGTCAGT
GAAGGCCTCTTGCTTGTCACCATCCTGGTGGGCTATGAGTGAGCACCTGTGGACACCAAACAGT
GTATGCTGCTCACTGCATGTTTTAGAAACAAAAGCAGCAGGCCTGACGAATCTGCAAGCATCAA
ATAAGCATGAGAGAGAGAAAAACAAAACCATGATATCTTACTTTACTTAAAGGGAAGGGCGGGT
GGGTGGGAGTCTCTGAAGTGTGAGTCTCAGTTATCTTTGGTTTAACCAGAATTCTGAATGCAAC
TTTGCAAGTTTTCTTTCCTTTACTCCCCACCCCCATCCCCCAATCTTTGAACCTTTGTAGCAAT
CCTTTCTGGGAGTCAGGGAAGGTAGAATCCTTTTCCTCACACTCCACCTCATAGCTCTCCCCAT
ACCGGTCCTCCTTGGCACCAAGGGCCTTCTGCAGGAGCTGGAGGGCCAGGTTCCATTCCAGAAA
GAGCCCTGTCTGCTTATGCATGTAGGTGACAGGAGAGACGCCCTCTCAATGAGGGTGTGCCTGC
CTGAGTGAGAAAGAATTTTGGGAGCTCTGCACAGCTTGTAAGTGTCAACAAAAGTGTACCATGA
AATGTTGTTTCTGGGTCTTGGGTCCATTCATATTTTATAGGCTTCTTGGGAGCTTGCTTCCGTG
GTGGTGGTGGTGGTGGGACAAGTCACGAATATTCAGGGTGAGCATGTAAACAGGCTCTTCTGAA
GAGTGTCCTGGAACCACAGCAGACACGGCAAAGCTGCCCTCCTCCCCAGAGCGCTGTGTGCTTC
CCATGTGCTTCTTCACTCACACCTACTTGGTACATTCTACAGTCAAGGGAGCCATACATAACAG
CCGCTGAAGCACCTCTTCCTCAGATAGAGCGAGGTGTGGGAACTTGTGGTGAGGAAAGGGAGGA
TGAGACTGTTTATTATGTGCACCAGCGGGTGGCAGGATGTGACAGTGTTTCCTGAAGCAAGGAA
GTCCCAGCTCATGGGAGCCTGGAGTTAGAGGGCAAAGGTGCCGGGGTTACCTGGAATATGGGGA
ACAAGAGTCAGCAGCAAAAGCAAAGTAAAACATCCAATATGAAATCAGTTCTTCAAAGTAAAAC
ATCCAATATGAAATCAGTTCTTGAGGCCCAGCAGAGCCGACAGGCGAGTGCTGGGGACCTTCTG
AGAAGGCAGTGTGCACATTCAGAGAGTGGTGGTGGCGGTGCTGGGTCCTTGACTAGACCAGGTT
AGATGGTAATGGAGAAAGCAGGGAGGTCTGTGTGTGTTCTTGGAGCCAAATCACAGGGACATTC
AGGAGTGTTTAGCTGTCGTGGTGACAGGGCTGAGAAAGCAGATGTCAGTAAATCTTTATGAGTC
CTGACAGGTGTTGTAATAAACCTCAACAAATCCATACCCTCTGTATAAAGGAAGTGAGGTCTTA
CAAAATGGGGAGGGTCGAGGTCATTCCTCACATAGCTTCAACCATTATTATGCGTTTTCTTCCC
ACCAAGTTAGGAAGATCGGCTCTGAGCGGTATCGTACGGGTCCATGGTGTCCCTGGCACAGACG
GTCATGCCTGGCCTCCCAGTCAGTCTTCATGGTCAGTTGGTGTAAGTGCTGCCCACCACCAGGA
AAGGAGGGGTTGTTTGGAGACGCCATTTCCACACATGGCTCTGTCTTTAGACTGCACAGTGTCA
CACAAGCCAAATAACCTCGCTGTGCCTTAGTGTCTCGTGGAGGAGACATTACCTGACCCAGGGA
CTACCTCAGGGGAGTTTTGTGAGAGGAAAAGAGAGTAAAGTGGGAAGACTCAAGGGCCTTTGGT
ACCAAGGTTCTCGGTGCCGACTACTACGTGCTACACTCTCCAGGAAGTTAAAAGGGAGTCGATG
ACCCTTCCCACCTGTGGCCAATTGAATCAGAACCTCAGGTAACGAGATGCCTTGAGGTGCCTTG
AAACATTACTTCGGTAAGGAGAACAAACACATTATTATCTTGGAAGAATCACTTAAGGATTAGG
CTAAAAAAAAATACTCTTTGAAGCAAGCGGTTCTGTAAGAACAATCAGATGTTGATACGTGTAT
TCATATATAAGTATTATCCGAGCAGTCTCTCAGTTTGCTTCTCATCCAAGCATCTGGAAAAAAA
ATCAAACATGCTTTCATTTACCTGAGCAGCGTATCAAGTCCTTGATAGCAAATGTACACAGACA
CGAATCTATAAATCTAATAATATATACTAGAGTTATTCGTTAATTATGGGAGAAATGCCCCTCC
CCTCACACTTGACTTCAATGGCAATTACTATAAAGTCCATTTTGCCAAGAATATATAAGTGCCT
CTGTGTTGTGAGGTAGCATGGAGCTGGCGTGCACACCAGCTGGCAGTGTGTTTCGGTGGCTCTG
CGGGATGACACATGCACAGGACACTGGGGAGTGGGGGAGATGGCCCGTGATCCACAGCGCCAGC
CCGGGGCAGTGATGCTATGAGGTGTTCTTATGAACAGCTGCGGTTGTGTTCATGGGCAAACTCA
GTCCTGTCGTGACTGTGGCAGGGAGGAGGGGATCCGTGAACAAAATGACAGGGTGCCAAAGTGG
GCTGCATGTGGGATGTGGGTGCTGTCGTGAGGACTCGGTGGTTGATGTATGTGCCTCCAGCCCT
GGACACGGAGCCTGCACCTAAGAGGAAATTTCTGAAAGAAGGCAACTATATGAATGTTTTAAAT
GCTTGGAGCATTAAAGATATTTCAAATGTT

hide sequence

RefSeq Acc Id:

XM_039104213 ⟹ XP_038960141

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	116,298,813 - 116,328,538 (+)	NCBI

RefSeq Acc Id:

XR_005501768

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	116,298,814 - 116,328,538 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_612545	(Get FASTA)	NCBI Sequence Viewer
	XP_006235008	(Get FASTA)	NCBI Sequence Viewer
	XP_038960141	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD10402	(Get FASTA)	NCBI Sequence Viewer
	AAF18465	(Get FASTA)	NCBI Sequence Viewer
	EDL80147	(Get FASTA)	NCBI Sequence Viewer
	Q9QXJ0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_612545 ⟸ NM_138536

- UniProtKB:

Q9Z1E5 (UniProtKB/Swiss-Prot), Q9QXJ0 (UniProtKB/Swiss-Prot), G3V8C8 (UniProtKB/TrEMBL), A6HQ46 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MYTFVVRQENSSVYAEVSRLLLATGYWKRLRRDNPRFNLMLGGRNRLPFGRLGHEPGLAQLVNY
YRGADKLCRKASLVKLVKTSPELSESCSWFPESYVIHPTNLKTPVAPAQNGIQLPVSNSRTDER
EFFLASYNRKKEDGEGNVWIAKSSAGAKGEGILISSEASELLDFIDNQGQVHVIQKYLEHPLLL
EPGHRKFDIRSWVLVDHQYNIYLYREGVLRTASEPYHVDNFQDKTCHLTNHCIQKEYSKNYGKY
EEGNEMFFEEFNQYLTSALNITLENSILLQIKHIIRSCLMSVEPAISTKHLPYQSFQLLGFDFM
VDEELKVWLIEVNGAPACAQKLYAELCQGIVDIAISSVFPPPDTEQVPQQPAAFMKL

hide sequence

RefSeq Acc Id:	XP_006235008 ⟸ XM_006234946
- Peptide Label:	isoform X1
- UniProtKB:	Q9Z1E5 (UniProtKB/Swiss-Prot), Q9QXJ0 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MYTFVVRDENSSVYAEVSRLLLATGYWKRLRRDNPRFNLMLGERNRLPFGRLGHEPGLAQLVNY YRGADKLCRKASLVKLVKTSPELSESCSWFPESYVIYPTNLKTPVAPAQNGIQLPVSNSRTDER EFFLASYNRKKEDGEGNVWIAKSSAGAKGEGILISSEASELLDFIDNQGQVHVIQKYLEHPLLL EPGHRKFDIREGVLRTASEPYHVDNFQDKTCHLTNHCIQKEYSKNYGKYEEGNEMFFEEFNQYL TSALNITLENSILLQIKHIIRSCLMSVEPAISTKHLPYQSFQLLGFDFMVDEELKVWLIEVNGA PACAQKLYAELCQGIVDIAISSVFPPPDTEQVPQQPAAFMKL hide sequence

RefSeq Acc Id:

ENSRNOP00000024695 ⟸ ENSRNOT00000024694

RefSeq Acc Id:	XP_038960141 ⟸ XM_039104213
- Peptide Label:	isoform X2
- UniProtKB:	Q9Z1E5 (UniProtKB/Swiss-Prot), Q9QXJ0 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:

ENSRNOP00000090593 ⟸ ENSRNOT00000109318

Protein Domains

TTL

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9QXJ0-F1-model_v2	AlphaFold	Q9QXJ0	1-377	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621113	AgrOrtholog
BioCyc Gene	G2FUF-47927	BioCyc
Ensembl Genes	ENSRNOG00000018205	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000024695	ENTREZGENE
	ENSRNOP00000024695.5	UniProtKB/TrEMBL
	ENSRNOP00000090593	ENTREZGENE
	ENSRNOP00000090593.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000024694	ENTREZGENE
	ENSRNOT00000024694.7	UniProtKB/TrEMBL
	ENSRNOT00000109318	ENTREZGENE
	ENSRNOT00000109318.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.11480	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ATP-grasp fold, B domain	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	TTL/TTLL_fam	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:171572	UniProtKB/Swiss-Prot
NCBI Gene	171572	ENTREZGENE
PANTHER	TUBULIN--TYROSINE LIGASE	UniProtKB/Swiss-Prot
	TUBULIN--TYROSINE LIGASE	UniProtKB/Swiss-Prot
	TUBULIN--TYROSINE LIGASE	UniProtKB/TrEMBL
	TUBULIN--TYROSINE LIGASE	UniProtKB/TrEMBL
Pfam	TTL	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Ttl	PhenoGen
PROSITE	TTL	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Glutathione synthetase ATP-binding domain-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6GIC1_RAT	UniProtKB/TrEMBL
	A6HQ46	ENTREZGENE, UniProtKB/TrEMBL
	G3V8C8	ENTREZGENE, UniProtKB/TrEMBL
	Q9QXJ0	ENTREZGENE
	Q9Z1E5	ENTREZGENE
	TTL_RAT	UniProtKB/Swiss-Prot
UniProt Secondary	Q9Z1E5	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Ttl	tubulin tyrosine ligase			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Ttl	tubulin tyrosine ligase			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	highly expressed in both undifferentiated myoblasts and cross-striated, contractile myotubes	634442

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar