Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Uba3 (ubiquitin-like modifier activating enzyme 3) Rattus norvegicus
Symbol: Uba3
Name: ubiquitin-like modifier activating enzyme 3
RGD ID: 621084
Description: Exhibits NEDD8 activating enzyme activity and nuclear receptor binding activity. Involved in negative regulation of transcription, DNA-templated. Predicted to localize to cytoplasm; nucleus; and protein-containing complex. Orthologous to human UBA3 (ubiquitin like modifier activating enzyme 3); PARTICIPATES IN neddylation pathway; proteasome degradation pathway involving cullin-dependent ubiquitin ligases; ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: NEDD8-activating enzyme E1 catalytic subunit; NEDD8-activating enzyme E1C; Ube1c; ubiquitin-activating enzyme 3; ubiquitin-activating enzyme E1C; ubiquitin-activating enzyme E1C (UBA3 homolog, yeast); ubiquitin-like modifier-activating enzyme 3
Homo sapiens (human) : UBA3 (ubiquitin like modifier activating enzyme 3)  HGNC  Alliance
Mus musculus (house mouse) : Uba3 (ubiquitin-like modifier activating enzyme 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Uba3 (ubiquitin like modifier activating enzyme 3)
Pan paniscus (bonobo/pygmy chimpanzee) : UBA3 (ubiquitin like modifier activating enzyme 3)
Canis lupus familiaris (dog) : UBA3 (ubiquitin like modifier activating enzyme 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Uba3 (ubiquitin like modifier activating enzyme 3)
Sus scrofa (pig) : UBA3 (ubiquitin like modifier activating enzyme 3)
Chlorocebus sabaeus (African green monkey) : UBA3 (ubiquitin like modifier activating enzyme 3)
Heterocephalus glaber (naked mole-rat) : Uba3 (ubiquitin like modifier activating enzyme 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04129,548,411 - 129,569,550 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4129,548,416 - 129,569,470 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04194,051,838 - 194,072,937 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44131,902,438 - 131,924,610 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14132,147,288 - 132,169,460 (-)NCBI
Celera4118,665,559 - 118,686,969 (-)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Uba3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621084
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.