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Gene: Uba3 (ubiquitin-like modifier activating enzyme 3) Rattus norvegicus
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Symbol: Uba3
Name: ubiquitin-like modifier activating enzyme 3
Description: Exhibits NEDD8 activating enzyme activity; nuclear receptor binding activity; and protein heterodimerization activity. Involved in negative regulation of transcription, DNA-templated. Predicted to localize to the cytoplasm; nucleus; and protein-containing complex. Orthologous to human UBA3 (ubiquitin like modifier activating enzyme 3); PARTICIPATES IN neddylation pathway; proteasome degradation pathway involving cullin-dependent ubiquitin ligases; ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: NEDD8-activating enzyme E1 catalytic subunit; NEDD8-activating enzyme E1C; Ube1c; ubiquitin-activating enzyme 3; ubiquitin-activating enzyme E1C; ubiquitin-activating enzyme E1C (UBA3 homolog, yeast); ubiquitin-like modifier-activating enzyme 3
Orthologs:
Homo sapiens (human) : UBA3 (ubiquitin like modifier activating enzyme 3)  HGNC  Alliance
Mus musculus (house mouse) : Uba3 (ubiquitin-like modifier activating enzyme 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Uba3 (ubiquitin like modifier activating enzyme 3)
Pan paniscus (bonobo/pygmy chimpanzee) : UBA3 (ubiquitin like modifier activating enzyme 3)
Canis lupus familiaris (dog) : UBA3 (ubiquitin like modifier activating enzyme 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Uba3 (ubiquitin like modifier activating enzyme 3)
Sus scrofa (pig) : UBA3 (ubiquitin like modifier activating enzyme 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04129,548,411 - 129,569,550 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04194,051,838 - 194,072,937 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44131,902,438 - 131,924,610 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14132,147,288 - 132,169,460 (-)NCBI
Celera4118,665,559 - 118,686,969 (-)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Uba3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621084
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.