Pex2 (peroxisomal biogenesis factor 2) - Rat Genome Database

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Gene: Pex2 (peroxisomal biogenesis factor 2) Mus musculus
Analyze
Symbol: Pex2
Name: peroxisomal biogenesis factor 2
RGD ID: 62106
MGI Page MGI
Description: Predicted to enable ubiquitin protein ligase activity. Involved in peroxisome organization. Acts upstream of or within several processes, including bile acid biosynthetic process; cholesterol homeostasis; and regulation of cholesterol biosynthetic process. Predicted to be located in peroxisome. Predicted to be part of Cdc73/Paf1 complex. Predicted to be active in peroxisomal membrane. Is expressed in several structures, including central nervous system and genitourinary system. Human ortholog(s) of this gene implicated in peroxisomal biogenesis disorder and peroxisome biogenesis disorder 5A. Orthologous to human PEX2 (peroxisomal biogenesis factor 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 35kDa; D3Ertd138; D3Ertd138e; PAF-1; peroxin-2; peroxisomal membrane protein 3; peroxisomal membrane protein 3, 35 kDa; peroxisome assembly factor 1; peroxisome biogenesis factor 2; PMP; PMP35; Pxm; Pxmp3; Zellweger syndrome homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3935,625,248 - 5,643,655 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl35,625,248 - 5,641,299 (-)EnsemblGRCm39 Ensembl
GRCm3835,560,188 - 5,578,596 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl35,560,188 - 5,576,239 (-)EnsemblGRCm38mm10GRCm38
MGSCv3735,560,188 - 5,576,239 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3635,543,577 - 5,559,201 (-)NCBIMGSCv36mm8
Celera35,637,555 - 5,653,606 (-)NCBICelera
Cytogenetic Map3A1NCBI
cM Map31.96NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal adrenal cortex morphology  (IAGP)
abnormal bile composition  (IAGP)
abnormal brain white matter morphology  (IAGP)
abnormal cerebellar foliation  (IAGP)
abnormal cerebellar granule layer morphology  (IAGP)
abnormal cerebellum external granule cell layer morphology  (IAGP)
abnormal cerebellum morphology  (IAGP)
abnormal circulating free fatty acids level  (IAGP)
abnormal frontal bone morphology  (IAGP)
abnormal gait  (IAGP)
abnormal head movements  (IAGP)
abnormal interparietal bone morphology  (IAGP)
abnormal kidney physiology  (IAGP)
abnormal liver morphology  (IAGP)
abnormal liver physiology  (IAGP)
abnormal motor capabilities/coordination/movement  (IAGP)
abnormal neurocranium morphology  (IAGP)
abnormal Purkinje cell morphology  (IAGP)
abnormal stratification in cerebral cortex  (IAGP)
aphagia  (IAGP)
cholestasis  (IAGP)
decreased bone mineral density  (IAGP)
decreased bone mineralization  (IAGP)
decreased brain size  (IAGP)
decreased cholesterol level  (IAGP)
decreased circulating cholesterol level  (IAGP)
decreased circulating HDL cholesterol level  (IAGP)
decreased embryo weight  (IAGP)
decreased liver cholesterol level  (IAGP)
decreased locomotor activity  (IAGP)
delayed intramembranous bone ossification  (IAGP)
hepatic steatosis  (IAGP)
impaired balance  (IAGP)
limb grasping  (IAGP)
microcephaly  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
small cerebellum  (IAGP)
trunk curl  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. A mouse model for Zellweger syndrome. Baes M, etal., Nat Genet. 1997 Sep;17(1):49-57.
2. Targeted deletion of the PEX2 peroxisome assembly gene in mice provides a model for Zellweger syndrome, a human neuronal migration disorder. Faust PL and Hatten ME, J Cell Biol. 1997 Dec 1;139(5):1293-305.
3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
4. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
5. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. MGD IEA MGD IEA
8. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. Mouse MP Annotation Import Pipeline RGD automated import pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1546315   PMID:7551822   PMID:8043297   PMID:10349636   PMID:10464095   PMID:10504404   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11161822   PMID:11217851   PMID:11478384  
PMID:12477932   PMID:12746876   PMID:14673138   PMID:16141072   PMID:16141073   PMID:16919269   PMID:18287559   PMID:19110480   PMID:19521500   PMID:19830841   PMID:21267068   PMID:21873635  
PMID:22441164   PMID:22988430   PMID:27597759   PMID:32733884   PMID:32968282   PMID:35235794   PMID:35756999   PMID:38329874   PMID:39069546  


Genomics

Comparative Map Data
Pex2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3935,625,248 - 5,643,655 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl35,625,248 - 5,641,299 (-)EnsemblGRCm39 Ensembl
GRCm3835,560,188 - 5,578,596 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl35,560,188 - 5,576,239 (-)EnsemblGRCm38mm10GRCm38
MGSCv3735,560,188 - 5,576,239 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3635,543,577 - 5,559,201 (-)NCBIMGSCv36mm8
Celera35,637,555 - 5,653,606 (-)NCBICelera
Cytogenetic Map3A1NCBI
cM Map31.96NCBI
PEX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38876,980,258 - 77,001,044 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl876,980,258 - 77,001,044 (-)EnsemblGRCh38hg38GRCh38
GRCh37877,892,494 - 77,913,280 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36878,055,049 - 78,075,079 (-)NCBINCBI36Build 36hg18NCBI36
Build 34878,057,712 - 78,074,994NCBI
Celera873,885,870 - 73,906,661 (-)NCBICelera
Cytogenetic Map8q21.13NCBI
HuRef873,378,964 - 73,399,755 (-)NCBIHuRef
CHM1_1877,944,088 - 77,964,880 (-)NCBICHM1_1
T2T-CHM13v2.0877,409,691 - 77,430,483 (-)NCBIT2T-CHM13v2.0
Pex2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8297,957,479 - 97,973,767 (+)NCBIGRCr8
mRatBN7.2296,050,380 - 96,072,928 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl296,045,958 - 96,073,404 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2102,587,325 - 102,603,512 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02100,708,411 - 100,724,598 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0295,763,317 - 95,779,508 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0298,251,756 - 98,269,185 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl298,252,925 - 98,269,184 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02117,990,545 - 118,007,746 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4298,361,891 - 98,378,715 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1298,306,852 - 98,323,677 (+)NCBI
Celera291,566,959 - 91,583,216 (+)NCBICelera
Cytogenetic Map2q23NCBI
Pex2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554443,811,973 - 3,830,666 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554443,811,972 - 3,830,666 (+)NCBIChiLan1.0ChiLan1.0
PEX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2792,717,778 - 92,735,460 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1868,345,570 - 68,363,805 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0873,508,349 - 73,526,560 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1875,145,061 - 75,163,338 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl875,146,255 - 75,147,172 (-)Ensemblpanpan1.1panPan2
PEX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12924,943,563 - 24,960,834 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2925,206,108 - 25,223,363 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02925,055,730 - 25,073,096 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2925,055,743 - 25,073,046 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12925,130,967 - 25,148,201 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02925,148,141 - 25,165,401 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02925,500,349 - 25,517,613 (-)NCBIUU_Cfam_GSD_1.0
Pex2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530354,180,390 - 54,197,777 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367021,573,650 - 1,591,004 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367021,573,616 - 1,626,323 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PEX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl459,252,337 - 59,270,116 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1459,252,330 - 59,270,117 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2464,716,680 - 64,745,314 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PEX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1872,513,975 - 72,532,399 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl872,514,307 - 72,517,003 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603968,748,476 - 68,767,273 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pex2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474414,240,570 - 14,245,183 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474414,227,430 - 14,245,082 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pex2
644 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:516
Count of miRNA genes:118
Interacting mature miRNAs:122
Transcripts:ENSMUST00000059021, ENSMUST00000071280, ENSMUST00000164828, ENSMUST00000165309
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301256Skmw1_mskeletal muscle weight 1 (mouse)Not determined3125786432Mouse
1300559Thypr3_mthymocyte proliferative response 3 (mouse)Not determined3452541938525519Mouse
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse

Markers in Region
AF031128  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3835,560,702 - 5,560,793UniSTSGRCm38
MGSCv3735,560,702 - 5,560,793UniSTSGRCm37
Celera35,638,069 - 5,638,160UniSTS
Cytogenetic Map3A1UniSTS
cM Map31.0UniSTS
Whitehead/MRC_RH3103.05UniSTS
BB282098  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3835,572,606 - 5,572,755UniSTSGRCm38
MGSCv3735,572,606 - 5,572,755UniSTSGRCm37
Celera35,649,973 - 5,650,122UniSTS
Cytogenetic Map3A1UniSTS
cM Map31.0UniSTS
Whitehead/MRC_RH3103.53UniSTS
RH126056  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3835,560,594 - 5,560,816UniSTSGRCm38
MGSCv3735,560,594 - 5,560,816UniSTSGRCm37
Celera35,637,961 - 5,638,183UniSTS
Cytogenetic Map3A1UniSTS
cM Map31.0UniSTS
AI233233  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3835,560,695 - 5,560,908UniSTSGRCm38
MGSCv3735,560,695 - 5,560,908UniSTSGRCm37
Celera35,638,062 - 5,638,275UniSTS
Cytogenetic Map3A1UniSTS
cM Map31.0UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001163301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001163302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001163305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001163306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001267714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001267715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006530058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006530059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011248140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017319505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030252469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030252470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030252471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030252472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030252475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC119876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF031128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB693393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC012404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX231604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX231749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX241668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L27842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000059021   ⟹   ENSMUSP00000059415
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl35,625,560 - 5,641,299 (-)Ensembl
GRCm38.p6 Ensembl35,560,500 - 5,576,239 (-)Ensembl
Ensembl Acc Id: ENSMUST00000071280   ⟹   ENSMUSP00000071255
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl35,625,564 - 5,641,188 (-)Ensembl
GRCm38.p6 Ensembl35,560,504 - 5,576,128 (-)Ensembl
Ensembl Acc Id: ENSMUST00000164828   ⟹   ENSMUSP00000129311
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl35,625,248 - 5,641,210 (-)Ensembl
GRCm38.p6 Ensembl35,560,188 - 5,576,150 (-)Ensembl
Ensembl Acc Id: ENSMUST00000165309   ⟹   ENSMUSP00000126445
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl35,625,248 - 5,641,210 (-)Ensembl
GRCm38.p6 Ensembl35,560,188 - 5,576,150 (-)Ensembl
Ensembl Acc Id: ENSMUST00000191916   ⟹   ENSMUSP00000141945
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl35,625,559 - 5,628,789 (-)Ensembl
GRCm38.p6 Ensembl35,560,499 - 5,563,729 (-)Ensembl
Ensembl Acc Id: ENSMUST00000195855   ⟹   ENSMUSP00000141927
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl35,625,560 - 5,641,205 (-)Ensembl
GRCm38.p6 Ensembl35,560,500 - 5,576,145 (-)Ensembl
RefSeq Acc Id: NM_001163301   ⟹   NP_001156773
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3935,625,248 - 5,641,308 (-)NCBI
GRCm3835,560,188 - 5,576,248 (-)NCBI
MGSCv3735,560,188 - 5,576,239 (-)RGD
Celera35,637,555 - 5,653,615 (-)NCBI
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001163302   ⟹   NP_001156774
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3935,625,248 - 5,641,308 (-)NCBI
GRCm3835,560,188 - 5,576,248 (-)NCBI
MGSCv3735,560,188 - 5,576,239 (-)RGD
Celera35,637,555 - 5,653,615 (-)NCBI
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001163305   ⟹   NP_001156777
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3935,625,248 - 5,641,308 (-)NCBI
GRCm3835,560,188 - 5,576,248 (-)NCBI
MGSCv3735,560,188 - 5,576,239 (-)RGD
Celera35,637,555 - 5,653,615 (-)NCBI
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001163306   ⟹   NP_001156778
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3935,625,248 - 5,641,308 (-)NCBI
GRCm3835,560,188 - 5,576,248 (-)NCBI
MGSCv3735,560,188 - 5,576,239 (-)RGD
Celera35,637,555 - 5,653,615 (-)NCBI
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001267714   ⟹   NP_001254643
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3935,625,248 - 5,641,308 (-)NCBI
GRCm3835,560,188 - 5,576,248 (-)NCBI
Celera35,637,555 - 5,653,615 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001267715   ⟹   NP_001254644
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3935,625,248 - 5,641,308 (-)NCBI
GRCm3835,560,188 - 5,576,248 (-)NCBI
Celera35,637,555 - 5,653,615 (-)NCBI
Sequence:
RefSeq Acc Id: NM_008994   ⟹   NP_033020
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3935,625,248 - 5,641,308 (-)NCBI
GRCm3835,560,188 - 5,576,248 (-)NCBI
MGSCv3735,560,188 - 5,576,239 (-)RGD
Celera35,637,555 - 5,653,615 (-)NCBI
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006530058   ⟹   XP_006530121
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3935,625,561 - 5,643,655 (-)NCBI
GRCm3835,560,499 - 5,578,596 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006530059   ⟹   XP_006530122
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3935,625,561 - 5,643,655 (-)NCBI
GRCm3835,560,499 - 5,578,596 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011248140   ⟹   XP_011246442
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3935,625,561 - 5,643,655 (-)NCBI
GRCm3835,560,499 - 5,578,596 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017319505   ⟹   XP_017174994
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3935,625,561 - 5,643,655 (-)NCBI
GRCm3835,560,499 - 5,578,596 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030252469   ⟹   XP_030108329
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3935,625,561 - 5,643,655 (-)NCBI
GRCm3835,560,499 - 5,578,596 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030252470   ⟹   XP_030108330
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3935,625,561 - 5,643,655 (-)NCBI
GRCm3835,560,499 - 5,578,596 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030252471   ⟹   XP_030108331
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3935,625,561 - 5,643,655 (-)NCBI
GRCm3835,560,499 - 5,578,596 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030252472   ⟹   XP_030108332
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3935,625,561 - 5,643,655 (-)NCBI
GRCm3835,560,499 - 5,578,596 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030252475   ⟹   XP_030108335
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3935,625,561 - 5,643,655 (-)NCBI
GRCm3835,560,499 - 5,578,596 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162962   ⟹   XP_036018855
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3935,625,561 - 5,643,655 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001156773 (Get FASTA)   NCBI Sequence Viewer  
  NP_001156774 (Get FASTA)   NCBI Sequence Viewer  
  NP_001156777 (Get FASTA)   NCBI Sequence Viewer  
  NP_001156778 (Get FASTA)   NCBI Sequence Viewer  
  NP_001254643 (Get FASTA)   NCBI Sequence Viewer  
  NP_001254644 (Get FASTA)   NCBI Sequence Viewer  
  NP_033020 (Get FASTA)   NCBI Sequence Viewer  
  XP_006530121 (Get FASTA)   NCBI Sequence Viewer  
  XP_006530122 (Get FASTA)   NCBI Sequence Viewer  
  XP_011246442 (Get FASTA)   NCBI Sequence Viewer  
  XP_017174994 (Get FASTA)   NCBI Sequence Viewer  
  XP_030108329 (Get FASTA)   NCBI Sequence Viewer  
  XP_030108330 (Get FASTA)   NCBI Sequence Viewer  
  XP_030108331 (Get FASTA)   NCBI Sequence Viewer  
  XP_030108332 (Get FASTA)   NCBI Sequence Viewer  
  XP_030108335 (Get FASTA)   NCBI Sequence Viewer  
  XP_036018855 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA21742 (Get FASTA)   NCBI Sequence Viewer  
  AAB91465 (Get FASTA)   NCBI Sequence Viewer  
  AAH12404 (Get FASTA)   NCBI Sequence Viewer  
  BAE27238 (Get FASTA)   NCBI Sequence Viewer  
  BAE30130 (Get FASTA)   NCBI Sequence Viewer  
  BAE31130 (Get FASTA)   NCBI Sequence Viewer  
  EDL05215 (Get FASTA)   NCBI Sequence Viewer  
  EDL05216 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000059415
  ENSMUSP00000059415.5
  ENSMUSP00000071255
  ENSMUSP00000071255.6
  ENSMUSP00000126445
  ENSMUSP00000126445.2
  ENSMUSP00000129311
  ENSMUSP00000129311.2
  ENSMUSP00000141927
  ENSMUSP00000141927.2
  ENSMUSP00000141945
  ENSMUSP00000141945.2
GenBank Protein P55098 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_033020   ⟸   NM_008994
- UniProtKB: Q91YZ5 (UniProtKB/TrEMBL),   Q3UJB7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001156774   ⟸   NM_001163302
- UniProtKB: Q91YZ5 (UniProtKB/TrEMBL),   Q3UJB7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001156773   ⟸   NM_001163301
- UniProtKB: Q91YZ5 (UniProtKB/TrEMBL),   Q3UJB7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001156777   ⟸   NM_001163305
- UniProtKB: Q91YZ5 (UniProtKB/TrEMBL),   Q3UJB7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001156778   ⟸   NM_001163306
- UniProtKB: Q91YZ5 (UniProtKB/TrEMBL),   Q3UJB7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001254643   ⟸   NM_001267714
- UniProtKB: Q91YZ5 (UniProtKB/TrEMBL),   Q3UJB7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001254644   ⟸   NM_001267715
- UniProtKB: Q91YZ5 (UniProtKB/TrEMBL),   Q3UJB7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006530121   ⟸   XM_006530058
- Peptide Label: isoform X1
- UniProtKB: Q91YZ5 (UniProtKB/TrEMBL),   Q3UJB7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006530122   ⟸   XM_006530059
- Peptide Label: isoform X1
- UniProtKB: Q91YZ5 (UniProtKB/TrEMBL),   Q3UJB7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011246442   ⟸   XM_011248140
- Peptide Label: isoform X1
- UniProtKB: Q91YZ5 (UniProtKB/TrEMBL),   Q3UJB7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017174994   ⟸   XM_017319505
- Peptide Label: isoform X1
- UniProtKB: Q91YZ5 (UniProtKB/TrEMBL),   Q3UJB7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030108331   ⟸   XM_030252471
- Peptide Label: isoform X1
- UniProtKB: Q91YZ5 (UniProtKB/TrEMBL),   Q3UJB7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030108335   ⟸   XM_030252475
- Peptide Label: isoform X1
- UniProtKB: Q91YZ5 (UniProtKB/TrEMBL),   Q3UJB7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030108329   ⟸   XM_030252469
- Peptide Label: isoform X1
- UniProtKB: Q91YZ5 (UniProtKB/TrEMBL),   Q3UJB7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030108332   ⟸   XM_030252472
- Peptide Label: isoform X1
- UniProtKB: Q91YZ5 (UniProtKB/TrEMBL),   Q3UJB7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030108330   ⟸   XM_030252470
- Peptide Label: isoform X1
- UniProtKB: Q91YZ5 (UniProtKB/TrEMBL),   Q3UJB7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000129311   ⟸   ENSMUST00000164828
Ensembl Acc Id: ENSMUSP00000071255   ⟸   ENSMUST00000071280
Ensembl Acc Id: ENSMUSP00000141945   ⟸   ENSMUST00000191916
Ensembl Acc Id: ENSMUSP00000126445   ⟸   ENSMUST00000165309
Ensembl Acc Id: ENSMUSP00000059415   ⟸   ENSMUST00000059021
Ensembl Acc Id: ENSMUSP00000141927   ⟸   ENSMUST00000195855
RefSeq Acc Id: XP_036018855   ⟸   XM_036162962
- Peptide Label: isoform X1
- UniProtKB: Q91YZ5 (UniProtKB/TrEMBL),   Q3UJB7 (UniProtKB/TrEMBL)
Protein Domains
RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P55098-F1-model_v2 AlphaFold P55098 1-305 view protein structure

Promoters
RGD ID:6834349
Promoter ID:MM_KWN:33700
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day3,   3T3L1_Day4,   ES_Cell
Transcripts:NM_001163302,   NM_001163303,   NM_001163304,   NM_001163305,   NM_001163306,   NM_008994,   UC008OOB.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3635,575,884 - 5,576,384 (-)MPROMDB
RGD ID:6880188
Promoter ID:EPDNEW_M3545
Type:initiation region
Name:Pex2_1
Description:Mus musculus peroxisomal biogenesis factor 2 , transcript variant8, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3835,576,144 - 5,576,204EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107486 AgrOrtholog
Ensembl Genes ENSMUSG00000040374 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000059021 ENTREZGENE
  ENSMUST00000059021.10 UniProtKB/TrEMBL
  ENSMUST00000071280 ENTREZGENE
  ENSMUST00000071280.8 UniProtKB/TrEMBL
  ENSMUST00000164828 ENTREZGENE
  ENSMUST00000164828.8 UniProtKB/TrEMBL
  ENSMUST00000165309 ENTREZGENE
  ENSMUST00000165309.8 UniProtKB/TrEMBL
  ENSMUST00000191916 ENTREZGENE
  ENSMUST00000191916.6 UniProtKB/TrEMBL
  ENSMUST00000195855 ENTREZGENE
  ENSMUST00000195855.6 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro PEX2/10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pex_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RING-HC_PEX2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19302 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:107486 ENTREZGENE
NCBI Gene 19302 ENTREZGENE
PANTHER PEROXISOME BIOGENESIS FACTOR 2 UniProtKB/Swiss-Prot
  PEROXISOME BIOGENESIS FACTOR 2 UniProtKB/Swiss-Prot
  PEROXISOME BIOGENESIS FACTOR 2 UniProtKB/TrEMBL
  PEROXISOME BIOGENESIS FACTOR 2 UniProtKB/TrEMBL
Pfam Pex2_Pex12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pex2 PhenoGen
PROSITE ZF_RING_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt P55098 ENTREZGENE, UniProtKB/Swiss-Prot
  Q3UJB7 ENTREZGENE, UniProtKB/TrEMBL
  Q91YZ5 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary O35467 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-07-31 Pex2  peroxisomal biogenesis factor 2  Pxmp3  peroxisomal membrane protein 3  Symbol and/or name change 5135510 APPROVED