Napa (NSF attachment protein alpha) - Rat Genome Database

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Gene: Napa (NSF attachment protein alpha) Rattus norvegicus
Analyze
Symbol: Napa
Name: NSF attachment protein alpha
RGD ID: 620855
Description: Enables syntaxin binding activity. Involved in positive regulation of ATP-dependent activity and protein-containing complex disassembly. Located in terminal bouton. Part of synaptobrevin 2-SNAP-25-syntaxin-1a complex. Is active in neuromuscular junction; postsynapse; and presynaptic active zone membrane. Orthologous to human NAPA (NSF attachment protein alpha); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,5-hexanedione; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: alpha-SNAP; alpha-soluble NSF attachment protein; N-ethylmaleimide sensitive fusion protein attachment protein alpha; N-ethylmaleimide-sensitive factor attachment protein, alpha; SNAP-alpha
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2176,787,036 - 76,805,869 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl176,786,932 - 76,805,869 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx182,161,106 - 82,179,706 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0190,725,130 - 90,743,730 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0183,916,205 - 83,934,791 (+)NCBIRnor_WKY
Rnor_6.0177,994,227 - 78,012,846 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl177,994,203 - 78,012,845 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0179,261,024 - 79,279,633 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4176,438,616 - 76,457,225 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1176,516,726 - 76,535,336 (+)NCBI
Celera171,277,383 - 71,295,992 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Syntaxin 6 functions in trans-Golgi network vesicle trafficking. Bock JB, etal., Mol Biol Cell. 1997 Jul;8(7):1261-71.
2. Mapping of the mouse hyh gene to a YAC/BAC contig on proximal Chromosome 7. Chae TH, etal., Mamm Genome 2002 May;13(5):239-44.
3. The hyh mutation uncovers roles for alpha Snap in apical protein localization and control of neural cell fate. Chae TH, etal., Nat Genet 2004 Mar;36(3):264-70. Epub 2004 Feb 1.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. NSF ATPase and alpha-/beta-SNAPs disassemble the AMPA receptor-PICK1 complex. Hanley JG, etal., Neuron 2002 Mar 28;34(1):53-67.
7. Structure and conformational changes in NSF and its membrane receptor complexes visualized by quick-freeze/deep-etch electron microscopy. Hanson PI, etal., Cell 1997 Aug 8;90(3):523-35.
8. A programmed ependymal denudation precedes congenital hydrocephalus in the hyh mutant mouse. Jimenez AJ, etal., J Neuropathol Exp Neurol 2001 Nov;60(11):1105-19.
9. Complexins: cytosolic proteins that regulate SNAP receptor function. McMahon HT, etal., Cell 1995 Oct 6;83(1):111-9.
10. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
11. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
12. Distribution of soluble N-ethylmaleimide fusion protein attachment proteins (SNAPs) in the rat nervous system. Nishiki T, etal., Neuroscience. 2001;107(3):363-71.
13. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
14. GOA pipeline RGD automated data pipeline
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. The female hysterical personality disorder. Schmidt DD and Messner E, J Fam Pract 1977 Mar;4(3):573-7.
17. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
18. Disassembly of all SNARE complexes by N-ethylmaleimide-sensitive factor (NSF) is initiated by a conserved 1:1 interaction between alpha-soluble NSF attachment protein (SNAP) and SNARE complex. Vivona S, etal., J Biol Chem. 2013 Aug 23;288(34):24984-91. doi: 10.1074/jbc.M113.489807. Epub 2013 Jul 8.
19. Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Wilhelm BG, etal., Science. 2014 May 30;344(6187):1023-8. doi: 10.1126/science.1252884.
Additional References at PubMed
PMID:9614193   PMID:11707603   PMID:14755058   PMID:15489334   PMID:16751776   PMID:16795052   PMID:17634366   PMID:18094056   PMID:18385322   PMID:19056867   PMID:19946888   PMID:21040848  
PMID:21700703   PMID:23376485   PMID:23533145   PMID:25278303   PMID:26156199   PMID:29476059   PMID:32357304  


Genomics

Comparative Map Data
Napa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2176,787,036 - 76,805,869 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl176,786,932 - 76,805,869 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx182,161,106 - 82,179,706 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0190,725,130 - 90,743,730 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0183,916,205 - 83,934,791 (+)NCBIRnor_WKY
Rnor_6.0177,994,227 - 78,012,846 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl177,994,203 - 78,012,845 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0179,261,024 - 79,279,633 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4176,438,616 - 76,457,225 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1176,516,726 - 76,535,336 (+)NCBI
Celera171,277,383 - 71,295,992 (+)NCBICelera
Cytogenetic Map1q21NCBI
NAPA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381947,484,530 - 47,515,063 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1947,487,637 - 47,515,091 (-)EnsemblGRCh38hg38GRCh38
GRCh371947,990,894 - 48,018,320 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361952,682,703 - 52,710,309 (-)NCBINCBI36Build 36hg18NCBI36
Build 341952,682,702 - 52,710,309NCBI
Celera1944,796,651 - 44,824,202 (-)NCBICelera
Cytogenetic Map19q13.32-q13.33NCBI
HuRef1944,419,062 - 44,446,529 (-)NCBIHuRef
CHM1_11947,993,097 - 48,020,681 (-)NCBICHM1_1
T2T-CHM13v2.01950,318,498 - 50,345,867 (-)NCBIT2T-CHM13v2.0
Napa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39715,832,127 - 15,851,907 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl715,832,383 - 15,851,900 (+)EnsemblGRCm39 Ensembl
GRCm38716,098,202 - 16,117,982 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl716,098,458 - 16,117,975 (+)EnsemblGRCm38mm10GRCm38
MGSCv37716,683,992 - 16,703,324 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36715,257,165 - 15,276,497 (+)NCBIMGSCv36mm8
Celera713,297,223 - 13,316,561 (+)NCBICelera
Cytogenetic Map7A2NCBI
cM Map78.74NCBI
Napa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555741,330,300 - 1,353,576 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555741,330,911 - 1,353,392 (-)NCBIChiLan1.0ChiLan1.0
NAPA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11953,135,166 - 53,162,757 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1953,135,166 - 53,162,757 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01944,479,871 - 44,507,315 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
NAPA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11108,510,920 - 108,533,317 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1108,510,931 - 108,532,881 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1107,992,649 - 108,015,048 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01109,036,933 - 109,059,339 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1109,036,946 - 109,059,336 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11108,703,923 - 108,726,316 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01108,348,707 - 108,371,092 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01109,217,202 - 109,239,603 (+)NCBIUU_Cfam_GSD_1.0
Napa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934919,537,428 - 19,560,366 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366641,155,557 - 1,178,631 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049366641,155,557 - 1,178,626 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NAPA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl653,246,968 - 53,275,265 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1653,249,330 - 53,275,304 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2648,743,003 - 48,768,919 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NAPA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1640,818,490 - 40,845,661 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl640,818,175 - 40,845,470 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607320,553,773 - 20,581,195 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Napa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248326,301,251 - 6,323,445 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Napa
43 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:102
Count of miRNA genes:76
Interacting mature miRNAs:91
Transcripts:ENSRNOT00000002044
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)11148131282174945Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)12887978078430678Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)13344984878449848Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)13344984878449848Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13483685879836858Rat
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13523959878430678Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13523959878430678Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14580314078430678Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14936146582174945Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)15389511782174945Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15389511782174945Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)17219768090508767Rat

Markers in Region
D1Rat317  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2176,788,574 - 76,788,802 (+)MAPPERmRatBN7.2
Rnor_6.0177,995,554 - 77,995,779NCBIRnor6.0
Rnor_5.0179,262,351 - 79,262,576UniSTSRnor5.0
RGSC_v3.4176,439,942 - 76,440,168RGDRGSC3.4
RGSC_v3.4176,439,943 - 76,440,168UniSTSRGSC3.4
RGSC_v3.1176,518,053 - 76,518,279RGD
Celera171,278,710 - 71,278,935UniSTS
FHH x ACI Map137.93RGD
FHH x ACI Map137.93UniSTS
Cytogenetic Map1q21UniSTS
PMC341847P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2176,805,220 - 76,805,729 (+)MAPPERmRatBN7.2
Rnor_6.0178,012,198 - 78,012,706NCBIRnor6.0
Rnor_5.0179,278,995 - 79,279,503UniSTSRnor5.0
RGSC_v3.4176,456,587 - 76,457,095UniSTSRGSC3.4
Celera171,295,354 - 71,295,862UniSTS
Cytogenetic Map1q21UniSTS
RH128512  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2176,805,544 - 76,805,725 (+)MAPPERmRatBN7.2
Rnor_6.0178,012,522 - 78,012,702NCBIRnor6.0
Rnor_5.0179,279,319 - 79,279,499UniSTSRnor5.0
RGSC_v3.4176,456,911 - 76,457,091UniSTSRGSC3.4
Celera171,295,678 - 71,295,858UniSTS
RH 3.4 Map1778.6UniSTS
Cytogenetic Map1q21UniSTS
RH138028  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2176,800,389 - 76,800,567 (+)MAPPERmRatBN7.2
Rnor_6.0178,007,367 - 78,007,544NCBIRnor6.0
Rnor_5.0179,274,164 - 79,274,341UniSTSRnor5.0
RGSC_v3.4176,451,756 - 76,451,933UniSTSRGSC3.4
Celera171,290,523 - 71,290,700UniSTS
RH 3.4 Map1777.4UniSTS
Cytogenetic Map1q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000002044   ⟹   ENSRNOP00000002044
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl176,787,184 - 76,805,869 (+)Ensembl
Rnor_6.0 Ensembl177,994,203 - 78,012,845 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093819   ⟹   ENSRNOP00000077298
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl176,786,932 - 76,805,866 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000103865   ⟹   ENSRNOP00000081324
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl176,786,932 - 76,805,866 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116376   ⟹   ENSRNOP00000080631
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl176,795,726 - 76,805,866 (+)Ensembl
RefSeq Acc Id: NM_080585   ⟹   NP_542152
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2176,787,248 - 76,805,859 (+)NCBI
Rnor_6.0177,994,227 - 78,012,836 (+)NCBI
Rnor_5.0179,261,024 - 79,279,633 (+)NCBI
RGSC_v3.4176,438,616 - 76,457,225 (+)RGD
Celera171,277,383 - 71,295,992 (+)RGD
Sequence:
RefSeq Acc Id: XM_039081759   ⟹   XP_038937687
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2176,787,036 - 76,805,869 (+)NCBI
RefSeq Acc Id: XM_039081799   ⟹   XP_038937727
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2176,787,055 - 76,805,869 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_542152   ⟸   NM_080585
- UniProtKB: P54921 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000002044   ⟸   ENSRNOT00000002044
RefSeq Acc Id: XP_038937687   ⟸   XM_039081759
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038937727   ⟸   XM_039081799
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000081324   ⟸   ENSRNOT00000103865
RefSeq Acc Id: ENSRNOP00000080631   ⟸   ENSRNOT00000116376
RefSeq Acc Id: ENSRNOP00000077298   ⟸   ENSRNOT00000093819

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P54921-F1-model_v2 AlphaFold P54921 1-295 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689724
Promoter ID:EPDNEW_R248
Type:initiation region
Name:Napa_1
Description:NSF attachment protein alpha
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0177,994,198 - 77,994,258EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620855 AgrOrtholog
BioCyc Gene G2FUF-60624 BioCyc
Ensembl Genes ENSRNOG00000001494 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000002044 ENTREZGENE
  ENSRNOP00000002044.5 UniProtKB/TrEMBL
  ENSRNOP00000077298 ENTREZGENE
  ENSRNOP00000077298.1 UniProtKB/TrEMBL
  ENSRNOP00000080631.1 UniProtKB/TrEMBL
  ENSRNOP00000081324.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002044 ENTREZGENE
  ENSRNOT00000002044.7 UniProtKB/TrEMBL
  ENSRNOT00000093819 ENTREZGENE
  ENSRNOT00000093819.1 UniProtKB/TrEMBL
  ENSRNOT00000103865.1 UniProtKB/TrEMBL
  ENSRNOT00000116376.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6921187 IMAGE-MGC_LOAD
InterPro NSF_attach UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:140673 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72716 IMAGE-MGC_LOAD
NCBI Gene 140673 ENTREZGENE
PANTHER PTHR13768 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Napa PhenoGen
PRINTS NSFATTACHMNT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZJF7_RAT UniProtKB/TrEMBL
  A0A8I5ZQH1_RAT UniProtKB/TrEMBL
  A0A8I5ZSQ9_RAT UniProtKB/TrEMBL
  A0A8L2PZF0_RAT UniProtKB/TrEMBL
  P54921 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-23 Napa  NSF attachment protein alpha  Napa  N-ethylmaleimide-sensitive factor attachment protein, alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-11 Napa  N-ethylmaleimide-sensitive factor attachment protein, alpha  Napa  N-ethylmaleimide sensitive fusion protein attachment protein alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-26 Napa  N-ethylmaleimide sensitive fusion protein attachment protein alpha      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Napa  N-ethylmaleimide sensitive fusion protein attachment protein alpha      Symbol and Name status set to provisional 70820 PROVISIONAL