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Gene: Gtf2f2 (general transcription factor IIF subunit 2) Rattus norvegicus
Symbol: Gtf2f2
Name: general transcription factor IIF subunit 2
Description: Predicted to have ATP binding activity; DNA binding activity; and helicase activity. Involved in positive regulation of RNA polymerase II transcriptional preinitiation complex assembly; positive regulation of transcription elongation from RNA polymerase II promoter; and transcription by RNA polymerase II. Localizes to the transcription factor TFIIH holo complex. Orthologous to human GTF2F2 (general transcription factor IIF subunit 2); PARTICIPATES IN RNA polymerase II transcription elongation pathway; RNA polymerase II transcription initiation pathway; INTERACTS WITH (+)-schisandrin B; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,4-dinitrotoluene.
Type: protein-coding
Also known as: ATP-dependent helicase GTF2F2; general transcription factor IIF, polypeptide 2; general transcription factor IIF, polypeptide 2 (30kD subunit); Rap30; TFIIF-beta; transcription factor gamma; transcription initiation factor IIF subunit beta; transcription initiation factor RAP30
Homo sapiens (human) : GTF2F2 (general transcription factor IIF subunit 2)  HGNC  Alliance
Mus musculus (house mouse) : Gtf2f2 (general transcription factor IIF, polypeptide 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gtf2f2 (general transcription factor IIF subunit 2)
Pan paniscus (bonobo/pygmy chimpanzee) : GTF2F2 (general transcription factor IIF subunit 2)
Canis lupus familiaris (dog) : GTF2F2 (general transcription factor IIF subunit 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gtf2f2 (general transcription factor IIF subunit 2)
Sus scrofa (pig) : GTF2F2 (general transcription factor IIF subunit 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01557,942,057 - 58,068,892 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01561,647,679 - 61,771,945 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41556,803,445 - 56,925,046 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11556,819,226 - 56,940,826 (-)NCBI
Celera1550,832,708 - 50,953,647 (-)NCBICelera
Cytogenetic Map15q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gtf2f2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620772
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.