Gstm3 (glutathione S-transferase mu 3) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Gstm3 (glutathione S-transferase mu 3) Rattus norvegicus
Analyze
Symbol: Gstm3
Name: glutathione S-transferase mu 3
RGD ID: 620381
Description: Predicted to enable glutathione transferase activity and identical protein binding activity. Predicted to act upstream of or within cellular response to xenobiotic stimulus and response to bacterium. Predicted to be located in cytoplasm. Biomarker of hypertension; PARTICIPATES IN glutathione conjugation pathway; glutathione metabolic pathway; phase I biotransformation pathway via cytochrome P450; .
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: glutathione S-transferase M3; glutathione S-transferase M4; glutathione S-transferase mu 3-like; glutathione S-transferase mu 3-like 1; glutathione S-transferase Yb4; glutathione S-transferase Yb4 gene; glutathione S-transferase, mu 3; Gstm3l; Gstm3l1; Gstm4; GstYb4
RGD Orthologs
Mouse
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82198,295,442 - 198,300,742 (-)NCBIGRCr8
GRCr8 Ensembl2198,295,442 - 198,300,667 (-)EnsemblGRCr8 Ensembl
mRatBN7.22195,590,450 - 195,612,578 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2195,607,289 - 195,612,475 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2203,250,033 - 203,254,795 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02201,132,155 - 201,136,917 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02195,949,108 - 195,953,870 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02210,761,729 - 210,766,501 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2210,761,729 - 210,766,501 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02230,213,463 - 230,235,414 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42203,532,363 - 203,537,135 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2188,254,140 - 188,258,912 (-)NCBICelera
RGSC_v3.12203,495,116 - 203,499,889 (-)NCBI
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Variation in genes relevant to aromatic hydrocarbon metabolism and the risk of adult brain tumors. De Roos AJ, etal., Neuro Oncol. 2006 Apr;8(2):145-55. Epub 2006 Jan 27.
2. Glutathione-S-transferase M1, M3, P1 and T1 polymorphisms and severity of lung disease in children with cystic fibrosis. Flamant C, etal., Pharmacogenetics. 2004 May;14(5):295-301.
3. Expression profiling identifies genes involved in emphysema severity. Francis SM, etal., Respir Res. 2009 Sep 2;10:81.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Proteomic analysis of peripheral T-lymphocytes in patients with asthma. Jeong HC, etal., Chest. 2007 Aug;132(2):489-96. Epub 2007 Jun 5.
6. Glutathione S-transferase GSTM3 and GSTP1 genotypes and larynx cancer risk. Jourenkova-Mironova N, etal., Cancer Epidemiol Biomarkers Prev. 1999 Feb;8(2):185-8.
7. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
8. Gene expression of rat glutathione S-transferases. Evidence for gene conversion in the evolution of the Yb multigene family. Lai HC, etal., J Biol Chem 1988 Aug 15;263(23):11389-95.
9. A GSTM3 polymorphism associated with an etiopathogenetic mechanism in Alzheimer disease. Maes OC, etal., Neurobiol Aging. 2010 Jan;31(1):34-45. Epub 2008 Apr 17.
10. Glutathione S-transferase polymorphisms in MS: their relationship to disability. Mann CL, etal., Neurology. 2000 Feb 8;54(3):552-7.
11. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
12. Glutathione S-transferase genotypes and allergic responses to diisocyanate exposure. Piirila P, etal., Pharmacogenetics. 2001 Jul;11(5):437-45.
13. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
14. GOA pipeline RGD automated data pipeline
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. Rationale for reclassification of a distinctive subdivision of mammalian class Mu glutathione S-transferases that are primarily expressed in testis. Rowe JD, etal., J Biol Chem 1998 Apr 17;273(16):9593-601.
17. Glutathione S-transferase polymorphisms in osteosarcoma patients. Salinas-Souza C, etal., Pharmacogenet Genomics. 2010 Aug;20(8):507-15.
18. Diet-relevant phytochemical intake affects the cardiac AhR and nrf2 transcriptome and reduces heart failure in hypertensive rats. Seymour EM, etal., J Nutr Biochem. 2013 Sep;24(9):1580-6. doi: 10.1016/j.jnutbio.2013.01.008. Epub 2013 Mar 22.
19. Glutathione S-transferase: genetics and role in toxicology. Strange RC, etal., Toxicol Lett 2000 Mar 15;112-113:357-63.
20. Glutathione S-transferase hGSTM3 and ageing-associated neurodegeneration: relationship to Alzheimer's disease. Tchaikovskaya T, etal., Mech Ageing Dev. 2005 Feb;126(2):309-15.
Additional References at PubMed
PMID:10587441   PMID:22871113   PMID:25416956   PMID:25931508  


Genomics

Comparative Map Data
Gstm3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82198,295,442 - 198,300,742 (-)NCBIGRCr8
GRCr8 Ensembl2198,295,442 - 198,300,667 (-)EnsemblGRCr8 Ensembl
mRatBN7.22195,590,450 - 195,612,578 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2195,607,289 - 195,612,475 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2203,250,033 - 203,254,795 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02201,132,155 - 201,136,917 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02195,949,108 - 195,953,870 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02210,761,729 - 210,766,501 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2210,761,729 - 210,766,501 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02230,213,463 - 230,235,414 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42203,532,363 - 203,537,135 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2188,254,140 - 188,258,912 (-)NCBICelera
RGSC_v3.12203,495,116 - 203,499,889 (-)NCBI
Cytogenetic Map2q34NCBI
Gstm3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393107,871,019 - 107,876,484 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3107,871,012 - 107,876,599 (-)EnsemblGRCm39 Ensembl
GRCm383107,963,696 - 107,969,174 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3107,963,696 - 107,969,283 (-)EnsemblGRCm38mm10GRCm38
MGSCv373107,766,614 - 107,772,076 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363108,091,752 - 108,097,214 (-)NCBIMGSCv36mm8
Celera3110,296,772 - 110,302,234 (-)NCBICelera
Cytogenetic Map3F2.3NCBI
cM Map346.83NCBI

Variants

.
Variants in Gstm3
24 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:71
Count of miRNA genes:70
Interacting mature miRNAs:71
Transcripts:ENSRNOT00000025800
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2163997722225110681Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2169358774214358774Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170656145239614549Rat
631566Bp90Blood pressure QTL 900.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2149957381221199885Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)283465462229820014Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2138595962205135428Rat
1581576Pur7Proteinuria QTL 70.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)280396178220931218Rat
1581578Cm49Cardiac mass QTL 494.90.01heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2145807215220931416Rat
61458Bp10Blood pressure QTL 103.42arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2191709311217961898Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)278269809208420281Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2122597372215234002Rat
12879836Kidm61Kidney mass QTL 610.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2154723085199723085Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)280396178220931218Rat
12879837Am2Aortic mass QTL 20.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2154723085199723085Rat
12879838Cm86Cardiac mass QTL 860.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2154723085199723085Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2159440891205135267Rat
12879839Cm85Cardiac mass QTL 850.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2154723085199723085Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2196140964251540988Rat
1549833Bp257Blood pressure QTL 2570.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170652929215652929Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2159440891220931218Rat
4889834Pur24Proteinuria QTL 245.80.014urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)2171994826205135428Rat
1359031Bp275Blood pressure QTL 275arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2188565047233565047Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2192287802229609668Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
12879840Bw179Body weight QTL 1790.005body mass (VT:0001259)body weight (CMO:0000012)2154723085199723085Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2184856304229856304Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2184856304229856304Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2144882354205135428Rat
1298083Bp158Blood pressure QTL 1582.62arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2191709311217961898Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845182205135428Rat
1357991Ael2Aortic elastin QTL 24.20.000071aorta elastin amount (VT:0003905)aortic elastin2169227906214227906Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)283400752223709938Rat
1331745Bp203Blood pressure QTL 2034.377arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2192287802221089121Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2184856304229856304Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2192287802237287802Rat
1578671Bmd10Bone mineral density QTL 105.4femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)2175931416220931416Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660251712708Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)280396034220931416Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)278269809205135428Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2182024327227024327Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2159440760228950743Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2184482291229482291Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2143344967251712708Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2143746578205135428Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2143344967251712708Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2114384617215381366Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2145306936212705578Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2113746222205135428Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2186850607231850607Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2192287802237287802Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2114384617215381366Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660223841096Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2117415288205135428Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2182635347227635347Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)283465462225110681Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)247856345205135428Rat
631522Bp74Blood pressure QTL 740.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2175008837220008837Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2184856304229856304Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2165453811210453811Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2163253030208253030Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166372086229820014Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)276328396209350714Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 4 12 32 76 78 59 7 59 6 144 35 19 40 41 19

Sequence


Ensembl Acc Id: ENSRNOT00000025800   ⟹   ENSRNOP00000025800
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2210,761,729 - 210,766,501 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000051261   ⟹   ENSRNOP00000044720
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2198,295,442 - 198,300,667 (-)Ensembl
mRatBN7.2 Ensembl2195,607,289 - 195,612,475 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000072342   ⟹   ENSRNOP00000065389
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2198,219,647 - 198,222,731 (+)Ensembl
mRatBN7.2 Ensembl2195,531,495 - 195,534,553 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090430   ⟹   ENSRNOP00000070934
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2195,531,916 - 195,534,553 (+)Ensembl
RefSeq Acc Id: NM_020540   ⟹   NP_065415
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82198,295,442 - 198,300,667 (-)NCBI
mRatBN7.22195,607,278 - 195,612,503 (-)NCBI
Rnor_6.02210,761,729 - 210,766,501 (-)NCBI
Rnor_5.02230,213,463 - 230,235,414 (-)NCBI
RGSC_v3.42203,532,363 - 203,537,135 (-)RGD
Celera2188,254,140 - 188,258,912 (-)RGD
Sequence:
RefSeq Acc Id: XM_039103003   ⟹   XP_038958931
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82198,295,442 - 198,300,734 (-)NCBI
mRatBN7.22195,607,278 - 195,612,519 (-)NCBI
RefSeq Acc Id: XR_005500356
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82198,297,852 - 198,300,742 (-)NCBI
mRatBN7.22195,609,688 - 195,612,578 (-)NCBI
Protein Sequences
Protein RefSeqs NP_065415 (Get FASTA)   NCBI Sequence Viewer  
  XP_038958931 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD22630 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000044720
  ENSRNOP00000044720.6
RefSeq Acc Id: NP_065415   ⟸   NM_020540
- UniProtKB: D3ZVQ8 (UniProtKB/TrEMBL),   A6HUW7 (UniProtKB/TrEMBL),   Q9WU21 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000025800   ⟸   ENSRNOT00000025800
RefSeq Acc Id: XP_038958931   ⟸   XM_039103003
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000044720   ⟸   ENSRNOT00000051261
Ensembl Acc Id: ENSRNOP00000070934   ⟸   ENSRNOT00000090430
Ensembl Acc Id: ENSRNOP00000065389   ⟸   ENSRNOT00000072342
Protein Domains
GST C-terminal   GST N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V8H3-F1-model_v2 AlphaFold G3V8H3 1-218 view protein structure
AF-D3ZVQ8-F1-model_v2 AlphaFold D3ZVQ8 1-235 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691667
Promoter ID:EPDNEW_R2192
Type:initiation region
Name:Gstm3l_1
Description:glutathione S-transferase mu 3-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02210,766,529 - 210,766,589EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620381 AgrOrtholog
BioCyc Gene G2FUF-51646 BioCyc
Ensembl Genes ENSRNOG00000019058 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000049743 Ensembl
Ensembl Transcript ENSRNOT00000051261 ENTREZGENE
  ENSRNOT00000051261.7 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1050.10 UniProtKB/TrEMBL
  Glutaredoxin UniProtKB/TrEMBL
InterPro Glutathione-S-Trfase_C-like UniProtKB/TrEMBL
  Glutathione-S-Trfase_C_sf UniProtKB/TrEMBL
  Glutathione_S-Trfase UniProtKB/TrEMBL
  Glutathione_S-Trfase_N UniProtKB/TrEMBL
  GST_C UniProtKB/TrEMBL
  GST_mu UniProtKB/TrEMBL
  GST_superfamily UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
KEGG Report rno:57298 UniProtKB/TrEMBL
NCBI Gene 57298 ENTREZGENE
PANTHER GLUTATHIONE S-TRANSFERASE UniProtKB/TrEMBL
  GLUTATHIONE S-TRANSFERASE MU 1-RELATED UniProtKB/TrEMBL
  GLUTATHIONE S-TRANSFERASE MU 7 UniProtKB/TrEMBL
Pfam GST_C UniProtKB/TrEMBL
  GST_N UniProtKB/TrEMBL
PhenoGen Gstm3 PhenoGen
PRINTS GSTRNSFRASEM UniProtKB/TrEMBL
PROSITE GST_CTER UniProtKB/TrEMBL
  GST_NTER UniProtKB/TrEMBL
RatGTEx ENSRNOG00000019058 RatGTEx
  ENSRNOG00000049743 RatGTEx
Superfamily-SCOP GST_C_like UniProtKB/TrEMBL
  Thiordxn-like_fd UniProtKB/TrEMBL
UniProt A6HUW2_RAT UniProtKB/TrEMBL
  A6HUW7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZVQ8 ENTREZGENE, UniProtKB/TrEMBL
  Q9WU21 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-11-18 Gstm3  glutathione S-transferase mu 3  Gstm3l1  glutathione S-transferase mu 3-like 1  Data merged from RGD:11402080 737654 PROVISIONAL
2021-11-04 Gstm3  glutathione S-transferase mu 3  Gstm3l  glutathione S-transferase mu 3-like  Name and Symbol changed 629549 APPROVED
2021-11-04 Gstm3l1  glutathione S-transferase mu 3-like 1  Gstm3  glutathione S-transferase mu 3  Name and Symbol changed 629549 APPROVED
2017-02-10 Gstm3  glutathione S-transferase mu 3  NEWGENE_620381  glutathione S-transferase mu 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2017-02-10 Gstm3l  glutathione S-transferase mu 3-like  Gstm3  glutathione S-transferase mu 3  Name and Symbol changed 629549 APPROVED
2009-02-04 Gstm3  glutathione S-transferase mu 3  Gstm3  glutathione S-transferase M3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-03 Gstm3  glutathione S-transferase M3  Gstm3  glutathione S-transferase, mu 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-25 Gstm3  glutathione S-transferase, mu 3  Gstm4  glutathione S-transferase M4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Gstm4  glutathione S-transferase M4  GstYb4  glutathione S-transferase Yb4 gene  Symbol and Name updated 1299863 APPROVED
2002-08-07 GstYb4  glutathione S-transferase Yb4 gene      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in liver 632976