Chn2 (chimerin 2) - Rat Genome Database

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Gene: Chn2 (chimerin 2) Rattus norvegicus
Analyze
Symbol: Chn2
Name: chimerin 2
RGD ID: 620140
Description: Enables GTPase activator activity. Involved in acrosome assembly. Predicted to be located in synapse. Orthologous to human CHN2 (chimerin 2); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: beta-chimaerin; beta-chimerin; chimerin (chimaerin) 2; rho GTPase-activating protein 3
RGD Orthologs
Human
Mouse
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8484,478,989 - 84,738,068 (+)NCBIGRCr8
mRatBN7.2483,148,616 - 83,407,711 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl483,147,983 - 83,407,709 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx488,370,092 - 88,629,056 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0484,145,507 - 84,404,477 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0482,568,244 - 82,827,277 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0484,423,708 - 84,452,989 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl484,194,347 - 84,454,500 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04149,084,648 - 149,113,929 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4482,649,232 - 82,678,513 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1482,933,853 - 82,963,134 (+)NCBI
Celera478,252,779 - 78,282,084 (+)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dextran sulfate  (ISO)
dibenz[a,h]anthracene  (ISO)
dibenzo[a,l]pyrene  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
finasteride  (EXP)
flavonoids  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
L-methionine  (ISO)
leflunomide  (EXP,ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-Nitrosopyrrolidine  (ISO)
nicotinic acid  (EXP)
O-methyleugenol  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorononanoic acid  (ISO)
permethrin  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
quercetin  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tetrachloromethane  (EXP,ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)
synapse  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Germ cell beta-chimaerin, a new GTPase-activating protein for p21rac, is specifically expressed during the acrosomal assembly stage in rat testis. Leung T, etal., J Biol Chem 1993 Feb 25;268(6):3813-6.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8175705  


Genomics

Comparative Map Data
Chn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8484,478,989 - 84,738,068 (+)NCBIGRCr8
mRatBN7.2483,148,616 - 83,407,711 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl483,147,983 - 83,407,709 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx488,370,092 - 88,629,056 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0484,145,507 - 84,404,477 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0482,568,244 - 82,827,277 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0484,423,708 - 84,452,989 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl484,194,347 - 84,454,500 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04149,084,648 - 149,113,929 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4482,649,232 - 82,678,513 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1482,933,853 - 82,963,134 (+)NCBI
Celera478,252,779 - 78,282,084 (+)NCBICelera
Cytogenetic Map4q24NCBI
CHN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38729,146,591 - 29,514,328 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl729,146,547 - 29,514,328 (+)EnsemblGRCh38hg38GRCh38
GRCh37729,186,207 - 29,553,944 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map7p14.3NCBI
HuRef729,115,775 - 29,435,673 (+)NCBIHuRef
CHM1_1729,234,238 - 29,554,150 (+)NCBICHM1_1
T2T-CHM13v2.0729,284,405 - 29,652,211 (+)NCBIT2T-CHM13v2.0
Chn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39654,016,917 - 54,278,797 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl654,016,539 - 54,278,795 (+)EnsemblGRCm39 Ensembl
GRCm38654,039,932 - 54,301,812 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl654,039,554 - 54,301,810 (+)EnsemblGRCm38mm10GRCm38
MGSCv37653,989,926 - 54,251,806 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36654,202,399 - 54,231,388 (+)NCBIMGSCv36mm8
Celera654,569,510 - 54,833,021 (+)NCBICelera
Cytogenetic Map6B3NCBI
cM Map626.54NCBI
CHN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11442,217,678 - 42,513,370 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1442,217,739 - 42,512,188 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1441,652,123 - 41,947,336 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01442,159,196 - 42,454,949 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1442,159,050 - 42,454,964 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11442,276,263 - 42,571,902 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01441,955,181 - 42,250,617 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01442,313,119 - 42,608,875 (+)NCBIUU_Cfam_GSD_1.0

Variants

.
Variants in Chn2
1691 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:32
Count of miRNA genes:26
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000012655
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658103194791Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44043338885433388Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44345797688457976Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)478881294117676292Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)457486946102486946Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658115089733Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482798864152731274Rat
724522Bp146Blood pressure QTL 1462.20.0021arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)473630210118630210Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44043341485433414Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)481192555126192555Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
2300179Bmd50Bone mineral density QTL 505.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)460928534105928534Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)462933508114921294Rat
61364Iddm2Insulin dependent diabetes mellitus QTL 2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)478885890102684881Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
1578657Bss12Bone structure and strength QTL 128.9femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)460220938105220938Rat
1578658Bss13Bone structure and strength QTL 138femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)460220938105220938Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
2302051Pia28Pristane induced arthritis QTL 285.30.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)473630210118630210Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
738015Pia9Pristane induced arthritis QTL 94.50.048joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)480694870125694870Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473169846132642728Rat
2312569Pur19Proteinuria QTL 193.40.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)46588210796130297Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)436303261103194984Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)470808386115808386Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)478878504123878504Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462879517107879517Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)45843213392991462Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)481006124120102625Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45711443291360801Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
7394826Bw126Body weight QTL 1260.002body mass (VT:0001259)body weight gain (CMO:0000420)46293326987483707Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat


Sequence


Ensembl Acc Id: ENSRNOT00000012655   ⟹   ENSRNOP00000012655
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl483,376,899 - 83,406,175 (+)Ensembl
Rnor_6.0 Ensembl484,423,653 - 84,452,972 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000084256   ⟹   ENSRNOP00000070229
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl483,283,214 - 83,407,709 (+)Ensembl
Rnor_6.0 Ensembl484,194,347 - 84,454,500 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097181   ⟹   ENSRNOP00000083538
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl483,377,533 - 83,407,709 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097615   ⟹   ENSRNOP00000077359
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl483,147,983 - 83,407,709 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100224   ⟹   ENSRNOP00000077273
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl483,377,533 - 83,405,981 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101363   ⟹   ENSRNOP00000085806
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl483,147,983 - 83,407,709 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103158   ⟹   ENSRNOP00000093988
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl483,377,533 - 83,407,709 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000106897   ⟹   ENSRNOP00000096033
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl483,302,401 - 83,406,952 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112440   ⟹   ENSRNOP00000082836
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl483,374,505 - 83,407,709 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119878   ⟹   ENSRNOP00000089974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl483,377,533 - 83,407,709 (+)Ensembl
RefSeq Acc Id: NM_032084   ⟹   NP_114473
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8484,478,989 - 84,738,068 (+)NCBI
mRatBN7.2483,148,616 - 83,407,711 (+)NCBI
Rnor_6.0484,423,708 - 84,452,989 (+)NCBI
Rnor_5.04149,084,648 - 149,113,929 (+)NCBI
RGSC_v3.4482,649,232 - 82,678,513 (+)RGD
Celera478,252,779 - 78,282,084 (+)RGD
Sequence:
RefSeq Acc Id: XM_039108464   ⟹   XP_038964392
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8484,624,920 - 84,736,551 (+)NCBI
mRatBN7.2483,294,596 - 83,407,706 (+)NCBI
RefSeq Acc Id: XM_039108465   ⟹   XP_038964393
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8484,700,750 - 84,736,551 (+)NCBI
mRatBN7.2483,370,556 - 83,407,706 (+)NCBI
RefSeq Acc Id: XM_039108466   ⟹   XP_038964394
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8484,707,175 - 84,736,551 (+)NCBI
mRatBN7.2483,376,918 - 83,407,706 (+)NCBI
RefSeq Acc Id: XM_039108467   ⟹   XP_038964395
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8484,700,753 - 84,736,551 (+)NCBI
mRatBN7.2483,370,556 - 83,407,706 (+)NCBI
RefSeq Acc Id: XM_063286763   ⟹   XP_063142833
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8484,630,192 - 84,736,551 (+)NCBI
RefSeq Acc Id: XM_063286764   ⟹   XP_063142834
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8484,707,234 - 84,736,551 (+)NCBI
RefSeq Acc Id: NP_114473   ⟸   NM_032084
- UniProtKB: A0A8I5Y7G2 (UniProtKB/TrEMBL),   A6K0U4 (UniProtKB/TrEMBL),   A0A8I6A2H3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012655   ⟸   ENSRNOT00000012655
Ensembl Acc Id: ENSRNOP00000070229   ⟸   ENSRNOT00000084256
RefSeq Acc Id: XP_038964392   ⟸   XM_039108464
- Peptide Label: isoform X1
- UniProtKB: Q03070 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038964393   ⟸   XM_039108465
- Peptide Label: isoform X2
- UniProtKB: Q03070 (UniProtKB/Swiss-Prot),   G3V773 (UniProtKB/TrEMBL),   A6K0U6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964395   ⟸   XM_039108467
- Peptide Label: isoform X3
- UniProtKB: Q03070 (UniProtKB/Swiss-Prot),   A0A8I5ZYQ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964394   ⟸   XM_039108466
- Peptide Label: isoform X2
- UniProtKB: Q03070 (UniProtKB/Swiss-Prot),   G3V773 (UniProtKB/TrEMBL),   A6K0U6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000082836   ⟸   ENSRNOT00000112440
Ensembl Acc Id: ENSRNOP00000085806   ⟸   ENSRNOT00000101363
Ensembl Acc Id: ENSRNOP00000077273   ⟸   ENSRNOT00000100224
Ensembl Acc Id: ENSRNOP00000089974   ⟸   ENSRNOT00000119878
Ensembl Acc Id: ENSRNOP00000077359   ⟸   ENSRNOT00000097615
Ensembl Acc Id: ENSRNOP00000096033   ⟸   ENSRNOT00000106897
Ensembl Acc Id: ENSRNOP00000093988   ⟸   ENSRNOT00000103158
Ensembl Acc Id: ENSRNOP00000083538   ⟸   ENSRNOT00000097181
RefSeq Acc Id: XP_063142833   ⟸   XM_063286763
- Peptide Label: isoform X1
- UniProtKB: Q03070 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063142834   ⟸   XM_063286764
- Peptide Label: isoform X2
- UniProtKB: Q03070 (UniProtKB/Swiss-Prot),   A6K0U6 (UniProtKB/TrEMBL),   G3V773 (UniProtKB/TrEMBL)
Protein Domains
Phorbol-ester/DAG-type   Rho-GAP   SH2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q03070-F1-model_v2 AlphaFold Q03070 1-295 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620140 AgrOrtholog
BioCyc Gene G2FUF-44777 BioCyc
Ensembl Genes ENSRNOG00000009411 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012655.7 UniProtKB/TrEMBL
  ENSRNOT00000084256.2 UniProtKB/TrEMBL
  ENSRNOT00000097181.1 UniProtKB/TrEMBL
  ENSRNOT00000097615.1 UniProtKB/TrEMBL
  ENSRNOT00000100224.1 UniProtKB/TrEMBL
  ENSRNOT00000101363.1 UniProtKB/TrEMBL
  ENSRNOT00000103158.1 UniProtKB/TrEMBL
  ENSRNOT00000106897.1 UniProtKB/TrEMBL
  ENSRNOT00000112440.1 UniProtKB/TrEMBL
  ENSRNOT00000119878.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro C1-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chimaerin_SH2 UniProtKB/TrEMBL
  DAG/PE-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  N-chimaerin UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rho-type_GAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP_chimaerin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
KEGG Report rno:84031 UniProtKB/Swiss-Prot
NCBI Gene 84031 ENTREZGENE
PANTHER BETA-CHIMAERIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CHIMERIN FAMILY MEMBER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
PhenoGen Chn2 PhenoGen
PIRSF N-chimaerin UniProtKB/TrEMBL
PRINTS DAGPEDOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2DOMAIN UniProtKB/TrEMBL
PROSITE RHOGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009411 RatGTEx
SMART RhoGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SM00109 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
  SSF57889 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JXD5_RAT UniProtKB/TrEMBL
  A0A8I5Y1D7_RAT UniProtKB/TrEMBL
  A0A8I5Y7G2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZXE2_RAT UniProtKB/TrEMBL
  A0A8I5ZYQ0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A2H3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AAW8_RAT UniProtKB/TrEMBL
  A0A8I6AL03_RAT UniProtKB/TrEMBL
  A0A8I6GKJ0_RAT UniProtKB/TrEMBL
  A6K0U4 ENTREZGENE, UniProtKB/TrEMBL
  A6K0U6 ENTREZGENE, UniProtKB/TrEMBL
  CHIO_RAT UniProtKB/Swiss-Prot
  G3V773 ENTREZGENE, UniProtKB/TrEMBL
  Q03070 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-01 Chn2  chimerin 2  Chn2  chimerin (chimaerin) 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Chn2  chimerin (chimaerin) 2      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Chn2  chimerin (chimaerin) 2      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression present at testicular germ cells during acrosomal assembly 724725
gene_protein 34 kDa 724725