Pou3f4 (POU class 3 homeobox 4) - Rat Genome Database

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Gene: Pou3f4 (POU class 3 homeobox 4) Rattus norvegicus
Analyze
Symbol: Pou3f4
Name: POU class 3 homeobox 4
RGD ID: 61947
Description: Enables DNA-binding transcription factor activity; double-stranded DNA binding activity; and minor groove of adenine-thymine-rich DNA binding activity. Involved in transcription by RNA polymerase II. Located in nucleus. Human ortholog(s) of this gene implicated in X-linked deafness 2. Orthologous to human POU3F4 (POU class 3 homeobox 4); INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: brain-4; brain-specific homeobox/POU domain protein 4; brn-4; oct-9; octamer-binding protein 9; octamer-binding transcription factor 9; OTF-9; POU domain, class 3, transcription factor 4; RHS2; RHS2 class III POU protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X75,858,646 - 75,859,923 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX75,858,646 - 75,859,923 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX77,428,273 - 77,429,550 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0X80,870,563 - 80,871,840 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0X78,451,380 - 78,452,657 (+)NCBIRnor_WKY
Rnor_6.0X82,143,789 - 82,145,066 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX82,143,789 - 82,145,066 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X82,301,578 - 82,302,855 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X99,214,446 - 99,215,723 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X99,287,906 - 99,289,156 (+)NCBI
CeleraX77,112,524 - 77,113,801 (+)NCBICelera
Cytogenetic MapXq31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The molecular basis of X-linked deafness type 3 (DFN3) in two sporadic cases: identification of a somatic mosaicism for a POU3F4 missense mutation. de Kok YJ, etal., Hum Mutat. 1997;10(3):207-11.
2. Association between X-linked mixed deafness and mutations in the POU domain gene POU3F4. de Kok YJ, etal., Science. 1995 Feb 3;267(5198):685-8.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. POU domain transcription factor brain 4 confers pancreatic alpha-cell-specific expression of the proglucagon gene through interaction with a novel proximal promoter G1 element. Hussain MA, etal., Mol Cell Biol. 1997 Dec;17(12):7186-94.
6. RHS2, a POU domain-containing gene, and its expression in developing and adult rat. Le Moine C and Young WS 3rd, Proc Natl Acad Sci U S A 1992 Apr 15;89(8):3285-9.
7. Brain 4: a novel mammalian POU domain transcription factor exhibiting restricted brain-specific expression. Mathis JM, etal., EMBO J 1992 Jul;11(7):2551-61.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9105675   PMID:9889200   PMID:10587581   PMID:10868931   PMID:14681019   PMID:15574296   PMID:15655183   PMID:17141158   PMID:18231833   PMID:18831054   PMID:20105446   PMID:21663595  
PMID:26060893   PMID:31518606  


Genomics

Comparative Map Data
Pou3f4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X75,858,646 - 75,859,923 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX75,858,646 - 75,859,923 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX77,428,273 - 77,429,550 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0X80,870,563 - 80,871,840 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0X78,451,380 - 78,452,657 (+)NCBIRnor_WKY
Rnor_6.0X82,143,789 - 82,145,066 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX82,143,789 - 82,145,066 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X82,301,578 - 82,302,855 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X99,214,446 - 99,215,723 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X99,287,906 - 99,289,156 (+)NCBI
CeleraX77,112,524 - 77,113,801 (+)NCBICelera
Cytogenetic MapXq31NCBI
POU3F4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X83,508,290 - 83,512,127 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 EnsemblX83,508,290 - 83,512,127 (+)EnsemblGRCh38hg38GRCh38
GRCh37X82,763,298 - 82,767,135 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X82,649,941 - 82,651,431 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X82,569,445 - 82,570,920NCBI
CeleraX83,000,650 - 83,002,156 (+)NCBICelera
Cytogenetic MapXq21.1NCBI
HuRefX76,337,125 - 76,338,589 (+)NCBIHuRef
CHM1_1X82,657,165 - 82,658,671 (+)NCBICHM1_1
T2T-CHM13v2.0X81,941,865 - 81,945,703 (+)NCBIT2T-CHM13v2.0
Pou3f4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X109,857,985 - 109,862,714 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX109,857,886 - 109,860,813 (+)EnsemblGRCm39 Ensembl
GRCm38X110,814,379 - 110,819,108 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX110,814,280 - 110,817,207 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X108,009,804 - 108,010,889 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X107,017,184 - 107,018,269 (+)NCBIMGSCv36mm8
CeleraX97,632,784 - 97,633,869 (+)NCBICelera
Cytogenetic MapXE1NCBI
cM MapX48.2NCBI
Pou3f4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555292,726,133 - 2,727,218 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555292,726,121 - 2,727,311 (+)NCBIChiLan1.0ChiLan1.0
POU3F4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X82,666,699 - 82,668,337 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX82,666,757 - 82,667,842 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X72,563,887 - 72,568,233 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
POU3F4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X64,427,161 - 64,428,825 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX64,427,325 - 64,428,410 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX55,185,767 - 55,187,326 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X65,745,624 - 65,747,183 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX65,745,693 - 65,746,778 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X63,406,449 - 63,408,008 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X65,024,007 - 65,025,564 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X64,613,109 - 64,614,668 (+)NCBIUU_Cfam_GSD_1.0
Pou3f4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X58,133,789 - 58,135,350 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365474,454,239 - 4,455,460 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POU3F4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX66,765,105 - 66,766,190 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X66,765,044 - 66,766,642 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X76,477,799 - 76,479,225 (+)NCBISscrofa10.2Sscrofa10.2susScr3
POU3F4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X72,379,656 - 72,381,186 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX72,379,979 - 72,381,064 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660678,524,912 - 8,526,260 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pou3f4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248525,037,373 - 5,040,139 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248525,036,585 - 5,040,160 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
AU049792  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X75,859,919 - 75,860,082 (+)MAPPERmRatBN7.2
Rnor_6.0X82,145,063 - 82,145,225NCBIRnor6.0
Rnor_5.0X82,302,852 - 82,303,014UniSTSRnor5.0
RGSC_v3.4X99,215,720 - 99,215,882UniSTSRGSC3.4
CeleraX77,113,798 - 77,113,960UniSTS
Cytogenetic MapXq31UniSTS
Pou3f4  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X75,858,711 - 75,859,140 (+)MAPPERmRatBN7.2
Rnor_6.0X82,143,855 - 82,144,283NCBIRnor6.0
Rnor_5.0X82,301,644 - 82,302,072UniSTSRnor5.0
RGSC_v3.4X99,214,512 - 99,214,940UniSTSRGSC3.4
CeleraX77,112,590 - 77,113,018UniSTS
Cytogenetic MapXq31UniSTS
Pou3f4  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X75,858,764 - 75,859,739 (+)MAPPERmRatBN7.2
Rnor_6.0X82,143,908 - 82,144,882NCBIRnor6.0
Rnor_5.0X82,301,697 - 82,302,671UniSTSRnor5.0
RGSC_v3.4X99,214,565 - 99,215,539UniSTSRGSC3.4
CeleraX77,112,643 - 77,113,617UniSTS
Cytogenetic MapXq31UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X75294106120294106Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:38
Count of miRNA genes:33
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000003724
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hepatobiliary system nervous system renal system reproductive system
High
Medium 45
Low 2 2 2 29 10 6
Below cutoff 1 16 5 4 4 21 19

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000003724   ⟹   ENSRNOP00000003724
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX75,858,646 - 75,859,923 (+)Ensembl
Rnor_6.0 EnsemblX82,143,789 - 82,145,066 (+)Ensembl
RefSeq Acc Id: NM_017252   ⟹   NP_058948
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X75,858,646 - 75,859,923 (+)NCBI
Rnor_6.0X82,143,789 - 82,145,066 (+)NCBI
Rnor_5.0X82,301,578 - 82,302,855 (+)NCBI
RGSC_v3.4X99,214,446 - 99,215,723 (+)RGD
CeleraX77,112,524 - 77,113,801 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_058948 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA42042 (Get FASTA)   NCBI Sequence Viewer  
  CAA77855 (Get FASTA)   NCBI Sequence Viewer  
  EDM07095 (Get FASTA)   NCBI Sequence Viewer  
  P62516 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_058948   ⟸   NM_017252
- UniProtKB: P62516 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000003724   ⟸   ENSRNOT00000003724
Protein Domains
POU-specific

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P62516-F1-model_v2 AlphaFold P62516 1-361 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61947 AgrOrtholog
BioCyc Gene G2FUF-1848 BioCyc
Ensembl Genes ENSRNOG00000002784 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000003724 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000003724 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.260.40 UniProtKB/Swiss-Prot
InterPro Homeobox-like_sf UniProtKB/Swiss-Prot
  Homeobox_CS UniProtKB/Swiss-Prot
  Homeobox_dom UniProtKB/Swiss-Prot
  Lambda_DNA-bd_dom_sf UniProtKB/Swiss-Prot
  POU UniProtKB/Swiss-Prot
  POU_dom UniProtKB/Swiss-Prot
  TF_POU_3 UniProtKB/Swiss-Prot
KEGG Report rno:29589 UniProtKB/Swiss-Prot
NCBI Gene 29589 ENTREZGENE
Pfam Homeodomain UniProtKB/Swiss-Prot
  Pou UniProtKB/Swiss-Prot
PhenoGen Pou3f4 PhenoGen
PIRSF Transcription_factor_POU UniProtKB/Swiss-Prot
PRINTS POUDOMAIN UniProtKB/Swiss-Prot
PROSITE HOMEOBOX_1 UniProtKB/Swiss-Prot
  HOMEOBOX_2 UniProtKB/Swiss-Prot
  POU_1 UniProtKB/Swiss-Prot
  POU_2 UniProtKB/Swiss-Prot
  POU_3 UniProtKB/Swiss-Prot
SMART HOX UniProtKB/Swiss-Prot
  POU UniProtKB/Swiss-Prot
Superfamily-SCOP SSF46689 UniProtKB/Swiss-Prot
  SSF47413 UniProtKB/Swiss-Prot
UniProt P62516 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary P25216 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-24 Pou3f4  POU class 3 homeobox 4  Pou3f4  POU domain, class 3, transcription factor 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Pou3f4  POU domain, class 3, transcription factor 4      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference