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Gene: Ncf2em1Mcwi (neutrophil cytosolic factor 2; zinc finger nuclease induced mutant 1, Medical College of Wisconsin) Rattus norvegicus
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Symbol: Ncf2em1Mcwi
Name: neutrophil cytosolic factor 2; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
Description: This allele was made by ZFN mutagenesis. The resulting mutation is a 5-bp frameshift deletion in exon 2 (del 253-257)
ASSOCIATED WITH decreased NAD(P)H oxidase activity; decreased susceptibility to hypertension; ASSOCIATED WITH proteinuria; renal fibrosis
Type: allele  of Ncf2  
Also known as: Ncf2em1Mcwi
Is Marker For: Strains:   SS-Ncf2em1Mcwi   SS-Ncf2em1Mcwi-/-   SS-Nox4em2Ncf2em1Mcwi   SS-Tg(Slc12a1-Ncf2-2A-Luc)-Ncf2em1Mcwi  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Cytogenetic Map13 RGD


Disease Annotations
Phenotype Annotations
References - curated

Genomics

Related Rat Strains

Expression


Sequence

Nucleotide Sequences

Additional Information

 
More on Ncf2em1Mcwi
Alliance Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 5144089
Created: 2011-07-29
Species: Rattus norvegicus
Last Modified: 2011-07-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.