Plekha7<sup>em4Mcwi</sup> (pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin) - Rat Genome Database

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Gene: Plekha7em4Mcwi (pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin) Rattus norvegicus
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Symbol: Plekha7em4Mcwi
Name: pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin
RGD ID: 5143979
Description: This allele was made by ZFN mutagenesis. The resulting mutation is a 19-bp frameshift deletion in exon 8 (del 638-656)
ASSOCIATED WITH decreased susceptibility to hypertension; decreased systemic vascular resistance; decreased urine albumin level; ASSOCIATED WITH Cardiac Fibrosis; glomerulosclerosis; hypertension
Type: allele  of Plekha7  
Also known as: Plekha7em4Mcwi
Is Marker For: Strains:   SS-Plekha7em4Mcwi   SS-Plekha7em4Mcwi-/-  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Cytogenetic Map1 RGD


Disease Annotations     Click to see Annotation Detail View

References


Genomics


Related Rat Strains
The following Strains have been annotated to Plekha7em4Mcwi


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001144861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Rat Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type
Plekha7em4Mcwi-var1 chr1 185483638 185483656 GTCATCTCCCCGGTGGCCC - deletion

Additional Information