Pnma6e (PNMA family member 6E) - Rat Genome Database

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Gene: Pnma6e (PNMA family member 6E) Mus musculus
Analyze
Symbol: Pnma6e
Name: PNMA family member 6E
RGD ID: 5143222
MGI Page MGI
Description: Orthologous to human PNMA6E (PNMA family member 6E) and PNMA6F (PNMA family member 6F); INTERACTS WITH aflatoxin B1 (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Gm18336; paraneoplastic antigen MA3; predicted gene, 18336
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X72,438,793 - 72,442,418 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX72,440,045 - 72,442,342 (-)EnsemblGRCm39 Ensembl
GRCm38X73,396,889 - 73,398,712 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX73,396,439 - 73,398,736 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X70,642,228 - 70,644,051 (-)NCBIGRCm37MGSCv37mm9NCBIm37
CeleraX64,650,732 - 64,652,555 (-)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
aflatoxin B1  (ISO)

References

Genomics

Comparative Map Data
Pnma6e
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X72,438,793 - 72,442,418 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX72,440,045 - 72,442,342 (-)EnsemblGRCm39 Ensembl
GRCm38X73,396,889 - 73,398,712 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX73,396,439 - 73,398,736 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X70,642,228 - 70,644,051 (-)NCBIGRCm37MGSCv37mm9NCBIm37
CeleraX64,650,732 - 64,652,555 (-)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.3NCBI
PNMA6E
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X153,395,639 - 153,414,004 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX153,395,639 - 153,401,392 (-)EnsemblGRCh38hg38GRCh38
GRCh37X152,661,097 - 152,666,808 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X152,315,381 - 152,317,501 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX152,896,085 - 152,896,990 (-)NCBICelera
Cytogenetic MapXq28NCBI
CHM1_1X152,529,920 - 152,533,884 (-)NCBICHM1_1
T2T-CHM13v2.0X151,669,233 - 151,687,464 (-)NCBIT2T-CHM13v2.0
Pnma6e
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X156,254,009 - 156,259,971 (-)NCBIGRCr8
mRatBN7.2X151,103,531 - 151,108,630 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX151,103,755 - 151,106,037 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X157,423,258 - 157,426,356 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Cytogenetic MapXq37NCBI
PNMA6F
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X153,357,052 - 153,361,265 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X153,360,656 - 153,364,868 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X142,867,200 - 142,871,408 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X152,755,328 - 152,759,438 (-)NCBIpanpan1.1PanPan1.1panPan2
PNMA6E
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X121,218,147 - 121,220,896 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX106,551,366 - 106,558,265 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X124,360,147 - 124,367,124 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X120,132,775 - 120,139,877 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X122,646,715 - 122,653,711 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X122,410,291 - 122,417,050 (-)NCBIUU_Cfam_GSD_1.0
Pnma6e
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X118,527,248 - 118,556,701 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936809266,367 - 269,248 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC110257703
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X124,203,040 - 124,204,023 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PNMA6F
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606565,611,394 - 65,615,482 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Pnma6e
103 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:229
Count of miRNA genes:211
Interacting mature miRNAs:223
Transcripts:ENSMUST00000180787
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse
13208567Bmiq12_mbody mass index QTL 12 (mouse)X3526365377043606Mouse
1301009Pbwg7_mpostnatal body weight growth 7 (mouse)Not determinedX3911371473113814Mouse
4141565Pbwg21_mpostnatal body weight growth 21 (mouse)Not determinedX3911371473113814Mouse
1300794Spha2_msperm head anomaly 2 (mouse)Not determinedX3992149886260137Mouse
4142200Rtwq1_mreduced testis weight QTL 1 (mouse)Not determined4147706075477203Mouse
1301278Bdln1_mbody length 1 (mouse)Not determinedX4170210675702218Mouse
1300702Fcsa4_mfemoral cross-sectional area 4 (mouse)Not determinedX4602744480027567Mouse
4141630Gct6_mgranulosa cell tumorigenesis 6 (mouse)Not determined47179121129764756Mouse
25314311Syncl3_msynaptonemal complex length 3 (mouse)X5198887789743606Mouse
13824980Ferq1_mgenetic fertility QTL 1 (mouse)X54045360148782996Mouse
10412108Desp5_mdespair 5 (mouse)Not determinedX5472235188722351Mouse
13464140Hdlq108_mHDL QTL 108 (mouse)X5777196091771960Mouse
25314316Mlh1fc3_mMLH1 foci count 3 (mouse)X6134360689843606Mouse
25314318Sccor2_msynaptonemal complex length to mean MLH1 count ratio 2 (mouse)X7054360696543606Mouse
1357730Hstx1_mhybrid sterility, X chromosome 1 (mouse)Not determinedX7145385277600812Mouse
4141665Mhysq2_mmale hybrid sterility QTL 2 (mouse)Not determined71453852139203212Mouse
12879918Shm4_msperm head morphology 4 (mouse)X72072050102062720Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001419142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AL732461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000180787   ⟹   ENSMUSP00000146964
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX72,440,045 - 72,442,342 (-)Ensembl
GRCm38.p6 EnsemblX73,396,439 - 73,398,736 (-)Ensembl
RefSeq Acc Id: NM_001419142   ⟹   NP_001406071
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X72,438,793 - 72,442,418 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001406071 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000146964
  ENSMUSP00000146964.2
Reference Protein Sequences
RefSeq Acc Id: ENSMUSP00000146964   ⟸   ENSMUST00000180787
RefSeq Acc Id: NP_001406071   ⟸   NM_001419142
- UniProtKB: A0A140LIU8 (UniProtKB/TrEMBL)
Protein Domains
Paraneoplastic antigen Ma-like C-terminal   Paraneoplastic antigen Ma-like N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A140LIU8-F1-model_v2 AlphaFold A0A140LIU8 1-765 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:5010521 AgrOrtholog
Ensembl Genes ENSMUSG00000096966 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000180787 ENTREZGENE
  ENSMUST00000180787.3 UniProtKB/TrEMBL
InterPro PNMA UniProtKB/TrEMBL
  PNMA_C UniProtKB/TrEMBL
  PNMA_N UniProtKB/TrEMBL
MGD MGI:5010521 ENTREZGENE
NCBI Gene 100416956 ENTREZGENE
PANTHER PARANEOPLASTIC ANTIGEN MA6E UniProtKB/TrEMBL
  PTHR23095 UniProtKB/TrEMBL
Pfam PNMA UniProtKB/TrEMBL
  PNMA_N UniProtKB/TrEMBL
PhenoGen Pnma6e PhenoGen
UniProt A0A140LIU8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-04-10 Pnma6e  PNMA family member 6E  Gm18336  predicted gene, 18336  Symbol and/or name updated 27372883 PROVISIONAL