Mir5126 (microRNA 5126) - Rat Genome Database

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Gene: Mir5126 (microRNA 5126) Mus musculus
Analyze
Symbol: Mir5126
Name: microRNA 5126
RGD ID: 5134324
MGI Page MGI
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: mir-5126; mmu-mir-5126; mu-mir-5126
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39184,673,560 - 84,673,636 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl184,673,560 - 84,673,636 (+)EnsemblGRCm39 Ensembl
GRCm38184,695,839 - 84,695,915 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl184,695,839 - 84,695,915 (+)EnsemblGRCm38mm10GRCm38
Celera184,755,665 - 84,755,741 (+)NCBICelera
Cytogenetic Map1C5NCBI
cM Map143.42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:16381832   PMID:21037258   PMID:21403133  


Genomics

Variants

.
Variants in Mir5126
4 total Variants
miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:18306
Count of gene targets:9792
Count of transcripts:16906
Interacting mature miRNAs:mmu-miR-5126
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134760138150193871Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134760138150193871Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134760138150193871Mouse
1357721Sle17_msystematic lupus erythematosus susceptibility 17 (mouse)Not determined139132808126445310Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
10043965Obq24_mobesity QTL 24 (mouse)Not determined15089021684890216Mouse
4141305Tgq9_mtriglyceride QTL 9 (mouse)Not determined5142160585421605Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
1357741Nidd5k_mNidd5 on KK-A<y> (mouse)Not determined15597494889975057Mouse
4142467Wbcq1_mwhite blood cell quantitative locus 1 (mouse)Not determined15626621490266360Mouse
1357505Vtbt1_mvertebral trabecular bone trait 1 (mouse)Not determined15626621490266360Mouse
1558717Ses1a_msalmonella enteritidis susceptibility 1a (mouse)Not determined15672692290727077Mouse
1301933Insq6_minsulin QTL 6 (mouse)Not determined15672692290727077Mouse
14746998Mancz1_mmandible centroid size 1 (mouse)15794135191941351Mouse
14747009Manh49_mmandible shape 49 (mouse)15794135191941351Mouse
1300746Skl1_mskeletal size (tail length) 1 (mouse)Not determined15799197791992080Mouse
1357679Egrm1_mearly growth rate, maternal effect 1 (mouse)Not determined15799197791992080Mouse
1301162Skull1_mskull morphology 1 (mouse)Not determined15799197791992080Mouse
1301667Lxw5_mlupus BXSB x NZW 5 (mouse)Not determined15854919192549443Mouse
1301444Alcw5_malcohol withdrawal 5 (mouse)Not determined15854919192549443Mouse
1301748Abbp1_mA/J and C57BL/6 blood pressure 1 (mouse)Not determined162946755120529678Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163920002153557562Mouse
1302119Cia15_mcollagen induced arthritis 15 (mouse)Not determined16588900688496101Mouse
27095918Ulnl1_mulna length 1, 5 week (mouse)167339159129727737Mouse
4141625Emo4_memotionality 4 (mouse)Not determined6807134586235027Mouse
1302146Cocrb1_mcocaine related behavior 1 (mouse)Not determined170133533104139557Mouse
1300976Bmd19_mbone mineral density 19 (mouse)Not determined173266214108838414Mouse
4142394Mssq1_mmandible size and shape QTL 1 (mouse)Not determined73615692107615830Mouse
1301304Hrq3_mheart rate quantitative locus 3 (mouse)Not determined173615692107615830Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173755175147125370Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74516235148715579Mouse
1357847Jckm2_mjuvenile cystic kidney modifier 2 (mouse)Not determined174991977133290937Mouse
1300821Lore1_mloss of righting induced by ethanol 1 (mouse)Not determined17554919192941077Mouse
27095931Pglq1_mpelvic girdle length QTL 1, 5 week (mouse)175976637128527737Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)175976637148775742Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)175976637181327565Mouse
1558928Mord2_mmodifier of retinal degeneration 2 (mouse)Not determined177123115110536075Mouse
14697706Stsl3a_mSalmonella typhimurium susceptibility locus 3a (mouse)17747663795827725Mouse
14696691Malq1_mmean attack latency QTL 1 (mouse)17797663787927722Mouse
14696693Avd2q1_mattack value day 2 QTL 1 (mouse)17897771790927722Mouse
4141725Wbcq4_mwhite blood cell quantitative locus 4 (mouse)Not determined179858683113858791Mouse
12050069Nabq1_mnasal bone morphology QTL 1 (mouse)179858683113858791Mouse
13452395Leusq2_mleucocytosis susceptibility QTL 2 (mouse)180245593126386517Mouse
1302029Sst1_msusceptibility to tuberculosis 1 (mouse)Not determined18165211487130822Mouse
14696692Tavq1_mtotal attack value QTL 1 (mouse)18197771588427722Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782291982147125370Mouse
1357439Popoa_mpremature ovulation and primary oocyte arrest (mouse)Not determined182643189135615379Mouse
10412238Alpq5_malcohol preference QTL 5 (mouse)Not determined182832635116832635Mouse
12791004Aath7_maortic arch atherosclerosis 7 (mouse)182832635116832635Mouse
25394564Skmw49_mskeletal muscle weight 49, TA (mouse)18342011988552630Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000175513
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl184,673,560 - 84,673,636 (+)Ensembl
GRCm38.p6 Ensembl184,695,839 - 84,695,915 (+)Ensembl
RefSeq Acc Id: NR_039588
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39184,673,560 - 84,673,636 (+)NCBI
GRCm38184,695,839 - 84,695,915 (+)ENTREZGENE
Celera184,755,665 - 84,755,741 (+)ENTREZGENE
cM Map1 ENTREZGENE
Sequence:
Promoters
RGD ID:6874262
Promoter ID:EPDNEW_M581
Type:initiation region
Name:Mir5126_1
Description:Mus musculus microRNA 5126 , microRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38184,695,779 - 84,695,839EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000093254 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000175513 ENTREZGENE
MGD MGI:4950451 ENTREZGENE
miRBase MI0018038 ENTREZGENE
NCBI Gene 100628595 ENTREZGENE
PhenoGen Mir5126 PhenoGen
RNAcentral URS000016B496 RNACentral
  URS0000759AEF RNACentral