Mir5130 (microRNA 5130) - Rat Genome Database

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Gene: Mir5130 (microRNA 5130) Mus musculus
Analyze
Symbol: Mir5130
Name: microRNA 5130
RGD ID: 5134317
MGI Page MGI
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: mir-5130; mmu-mir-5130; mu-mir-5130
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914103,219,985 - 103,220,068 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14103,219,985 - 103,220,068 (-)EnsemblGRCm39 Ensembl
GRCm3814102,982,549 - 102,982,632 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14102,982,549 - 102,982,632 (-)EnsemblGRCm38mm10GRCm38
Celera14101,615,237 - 101,615,320 (-)NCBICelera
Cytogenetic Map14E2.3NCBI
cM Map1451.55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:16381832   PMID:21037258   PMID:21403133   PMID:30578296  


Genomics

Variants

.
Variants in Mir5130
2 total Variants
miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:9130
Count of gene targets:5334
Count of transcripts:8086
Interacting mature miRNAs:mmu-miR-5130
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
14747006Mancz12_mmandible centroid size 12 (mouse)1470071977104071977Mouse
10054475Ossc3_mosteosarcoma susceptibility 3 (mouse)Not determined1470863768104863926Mouse
1300551Lprm3_mlymphoproliferation modifier 3 (mouse)Not determined1471221224105221344Mouse
1301844Pgia29_mproteoglycan induced arthritis 29 (mouse)Not determined1474352296108352384Mouse
1558819Ossc2_mosteosarcoma susceptibility 2 (mouse)Not determined1474394976108395093Mouse
14928314Manh77_mmandible shape 77 (mouse)1476767790110767790Mouse
1558823Tbbmd6_mtotal body bone mineral density 6 (mouse)Not determined1477073696111073787Mouse
4142508Tgq25_mtriglyceride QTL 25 (mouse)Not determined85134068119134068Mouse
12792981Fbmd5_mfemoral bone mineral density 5, females only (mouse)1499838217125033054Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000175160
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl14103,219,985 - 103,220,068 (-)Ensembl
GRCm38.p6 Ensembl14102,982,549 - 102,982,632 (-)Ensembl
RefSeq Acc Id: NR_039592
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914103,219,985 - 103,220,068 (-)NCBI
GRCm3814102,982,549 - 102,982,632 (-)ENTREZGENE
Celera14101,615,237 - 101,615,320 (-)ENTREZGENE
cM Map14 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000092901 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000175160 ENTREZGENE
MGD MGI:4950455 ENTREZGENE
miRBase MI0018042 ENTREZGENE
NCBI Gene 100628599 ENTREZGENE
PhenoGen Mir5130 PhenoGen
RNAcentral URS0000353CC6 RNACentral
  URS000075D71E RNACentral