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Gene: MIR4497 (microRNA 4497) Homo sapiens
Analyze
Symbol: MIR4497
Name: microRNA 4497
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: mir-4497
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812109,833,348 - 109,833,436 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712110,271,153 - 110,271,241 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map12q24.11NCBI
HuRef12107,287,088 - 107,287,176 (+)NCBIHuRef
CHM1_112110,238,961 - 110,239,049 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
Gene-Chemical Interaction Annotations
References - uncurated

Genomics

miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Clinical Variants

Additional Information

External Database Links
  
More on MIR4497
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 5133895
Created: 2011-06-28
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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