MIR3664 (microRNA 3664) - Rat Genome Database
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Gene: MIR3664 (microRNA 3664) Homo sapiens
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Symbol: MIR3664
Name: microRNA 3664
RGD ID: 4888822
HGNC Page HGNC
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: mir-3664
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1170,872,270 - 70,872,368 (-)EnsemblGRCh38hg38GRCh38
GRCh381170,872,270 - 70,872,368 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371170,718,375 - 70,718,473 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map11q13.4NCBI
HuRef1166,980,207 - 66,980,305 (-)NCBIHuRef
CHM1_11170,601,794 - 70,601,892 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:16381832   PMID:20532037   PMID:21037258   PMID:21199797   PMID:30628643   PMID:31235820  


Genomics

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:44579
Count of gene targets:14863
Count of transcripts:30853
Interacting mature miRNAs:hsa-miR-3664-3p, hsa-miR-3664-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium
Low 5 6 18 8 10 7 23 2 7 9 13 30 2 4 6 1
Below cutoff 31 11 27 10 10 7 41 16 34 21 23 23 5 10 26 2

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000579074
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1170,872,270 - 70,872,368 (-)Ensembl
RefSeq Acc Id: NR_037437
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381170,872,270 - 70,872,368 (-)NCBI
GRCh371170,718,375 - 70,718,473 (-)ENTREZGENE
HuRef1166,980,207 - 66,980,305 (-)ENTREZGENE
CHM1_11170,601,794 - 70,601,892 (-)NCBI
Sequence:

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11q13.4(chr11:70575193-70893208)x1 copy number loss See cases [RCV000141941] Chr11:70575193..70893208 [GRCh38]
Chr11:70421298..70739313 [GRCh37]
Chr11:70098946..70416961 [NCBI36]
Chr11:11q13.4
uncertain significance
GRCh38/hg38 11q13.2-13.4(chr11:68031693-71593495)x1 copy number loss See cases [RCV000142138] Chr11:68031693..71593495 [GRCh38]
Chr11:67799160..71304541 [GRCh37]
Chr11:67555736..70982189 [NCBI36]
Chr11:11q13.2-13.4
likely pathogenic

Additional Information

Database Acc Id Source(s)
COSMIC MIR3664 COSMIC
Ensembl Genes ENSG00000263744 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000579074 ENTREZGENE
GTEx ENSG00000263744 GTEx
HGNC ID HGNC:38899 ENTREZGENE
Human Proteome Map MIR3664 Human Proteome Map
miRBase MI0016065 ENTREZGENE
NCBI Gene 100500844 ENTREZGENE
RNAcentral URS000043C1C3 RNACentral
  URS000075991E RNACentral
  URS000075CCEC RNACentral