Mir3474 (microRNA 3474) - Rat Genome Database

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Gene: Mir3474 (microRNA 3474) Mus musculus
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Symbol: Mir3474
Name: microRNA 3474
RGD ID: 4888707
MGI Page MGI
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: mir-3474; mmu-mir-3474
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392158,480,503 - 158,480,560 (+)NCBIGRCm39mm39
GRCm39 Ensembl2158,480,503 - 158,480,560 (+)Ensembl
GRCm382158,638,583 - 158,638,640 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2158,638,583 - 158,638,640 (+)EnsemblGRCm38mm10GRCm38
Celera2164,572,070 - 164,572,127 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map278.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:16381832   PMID:20215419   PMID:21037258  


Genomics


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301865Hdlq19_mHDL QTL 19 (mouse)Not determined2145676855179677006Mouse
1301588Hrec_mhemotopoietic response to early cytokines (mouse)Not determined2154711297159586530Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2118112449174483070Mouse
1301961Bts1_mbladder tumor susceptibility 1 (mouse)Not determined2132182239166182410Mouse
1302143Bwq5_mbody weight (mouse)Not determined2127822099161822198Mouse
1558842Tailq2_mtail length QTL 2 (mouse)Not determined2151799021162895154Mouse
1558852Gnf2_mgrowth and fatness 2 (mouse)Not determined2152857301162355165Mouse
1558867Gnf3_mgrowth and fatness 3 (mouse)Not determined2152857301169276004Mouse
1302013Tbbmd3_mtotal body bone mineral density 3 (mouse)Not determined2145355029179355165Mouse
4141033Wg2d_mweight gain in high growth mice 2d (mouse)Not determined143931525160461088Mouse
1301783Bhr1_mbronchial hyperresponsiveness 1 (mouse)Not determined2142751556178800659Mouse
1300806Aod4_mautoimmune ovarian dysgenesis 4 (mouse)Not determined2145386799179386921Mouse
1301907Rends_mrenal disease susceptibility (mouse)Not determined2135857301169857441Mouse
1300846Pbwg11_mpostnatal body weight growth 11 (mouse)Not determined2139124680173124809Mouse
1300867Lore2_mloss of righting induced by ethanol 2 (mouse)Not determined2144673941181254801Mouse
1300622Cfld1_mcystic fibrosis lung disease 1 (mouse)Not determined2155982127182113224Mouse
1357537Lith12_mlithogenic gene 12 (mouse)Not determined2156354671182113224Mouse
1300688Nidd2k_mNidd2 on KK-A (mouse)Not determined2158236417178800659Mouse
1300751Bdt1_mbone density traits 1 (mouse)Not determined2150146982182113224Mouse
1301019Bmd6_mbone mineral density 6 (mouse)Not determined2151936377182113224Mouse
1301031Bdln3_mbody length 3 (mouse)Not determined2127822099161822198Mouse
1357772Scfq1_msubcutaneous fat pad weight QTL 1 (mouse)Not determined2151799021162895154Mouse
1301085Lrnx10_mlearning-contextual 10 (mouse)Not determined2150370301182113224Mouse
1357862Epfq1_mepididymal fat pad weight QTL 1 (mouse)Not determined2151799021162895154Mouse
1357484Bsbob_mBSB obesity (mouse)Not determined2143931525165823099Mouse
1558917Gct8_mgranulosa cell tumorigenesis 8 (mouse)Not determined2149394987182113224Mouse
1558939Gnf1_mgrowth and fatness 1 (mouse)Not determined2143931525169276004Mouse
4142211Nilac3_mnicotine induced locomotor activity 3 (mouse)Not determined2148822973182113224Mouse
4141703Chlq13_mcirculating hormone level QTL 13 (mouse)Not determined2135857301169857441Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285893925181254801Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265439402162677006Mouse
10054066Bwq9_mbody weight QTL 9 (mouse)Not determined2135857301169857441Mouse
10043956Gnf5_mgrowth and fatness 5 (mouse)Not determined2135857301169857441Mouse
10412080Hylaq2_mHyperlocomotor activity related QTL 2 (mouse)Not determined2151799021164277226Mouse
4142450Lmr16_mleishmaniasis resistance 16 (mouse)Not determined2150370301182113224Mouse
12910799Pwgrq2_mpre-weaning growth rate QTL 2 (mouse)2118758772160769245Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102800000160100000Mouse
11049567Lmr28f_mleishmaniasis resistance 28f (mouse)2133302991167303138Mouse
11049566Lmr28e_mleishmaniasis resistance 28e (mouse)2133302991167303138Mouse
12910795Pwbwq5_mpost-weaning body weight QTL 5 (mouse)2118758772160769245Mouse
14747002Mancz3_mmandible centroid size 3 (mouse)2152487900182113224Mouse
12801461Intim1_mintima modifier 1 (mouse)2142586427176586530Mouse
11353826Bdln10_mbody length 10 (mouse)2140599562174599562Mouse
11341717Rvfs1_mRift Valley fever susceptibility 1 (mouse)2135590624173607823Mouse
12801456Intmrm1_mintima/media ratio modifier 1 (mouse)2142586427176586530Mouse
11038701Ltpr2e_mLeishmania tropica response 2e (mouse)2150370301182113224Mouse
12790983Bwq12_mbody weight QTL 12 (mouse)2148396284182113224Mouse
12910814Pwbwq1_mpre-weaning body weight QTL 1 (mouse)2118758772160769245Mouse
12910812Pwgrq1_mpre-weaning growth rate QTL 1 (mouse)2118758772160769245Mouse
12880427V25Dq3_mvitamin D inactive form serum level QTL 3 (mouse)2129500000163500000Mouse
12910520Scgq3_mspontaneous crescentic glomerulonephritis QTL 3 (mouse)2151867353174547331Mouse
27226749Femd10_mfemur midshaft diameter 10, 16 week (mouse)2124600000168400000Mouse
13825247Agoc2_magouti coat color QTL 2 (mouse)2152000000160000000Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103265371167370436Mouse

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:25728
Count of gene targets:11421
Count of transcripts:19440
Interacting mature miRNAs:mmu-miR-3474
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000175379
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl2158,638,583 - 158,638,640 (+)Ensembl
RefSeq Acc Id: NR_037312
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392158,480,503 - 158,480,560 (+)NCBI
GRCm382158,638,583 - 158,638,640 (+)ENTREZGENE
Celera2164,572,070 - 164,572,127 (+)ENTREZGENE
cM Map2 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000093120 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000175379 ENTREZGENE
MGD MGI:4441441 ENTREZGENE
miRBase MI0014707 ENTREZGENE
NCBI Gene 100499529 ENTREZGENE
PhenoGen Mir3474 PhenoGen
RNAcentral URS00003256E0 RNACentral
  URS000075ED44 RNACentral