Mir669p-2 (microRNA 669p-2) - Rat Genome Database

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Gene: Mir669p-2 (microRNA 669p-2) Mus musculus
Analyze
Symbol: Mir669p-2
Name: microRNA 669p-2
RGD ID: 4888631
MGI Page MGI
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: mmu-mir-669p-2
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39210,501,308 - 10,501,394 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl210,501,308 - 10,501,394 (+)EnsemblGRCm39 Ensembl
GRCm38210,496,497 - 10,496,583 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl210,496,497 - 10,496,583 (+)EnsemblGRCm38mm10GRCm38
Celera210,422,268 - 10,422,352 (+)NCBICelera
Cytogenetic Map2A1NCBI
cM Map28.22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:16381832   PMID:20413612  


Genomics

Variants

.
Variants in Mir669p-2
1 total Variants
miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:23668
Count of gene targets:9373
Count of transcripts:15162
Interacting mature miRNAs:mmu-miR-669p-3p, mmu-miR-669p-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10045633Heal15_mwound healing/regeneration 15 (mouse)Not determined2121989642Mouse
4141836Tgq11_mtriglyceride QTL 11 (mouse)Not determined125324559Mouse
4142333Tgq10_mtriglyceride QTL 10 (mouse)Not determined125324559Mouse
1301838Sluc16_msusceptibility to lung cancer 16 (mouse)Not determined2126529589Mouse
12904743Carcdq3_mcardiac collagen deposition QTL 3 (mouse)2323494028179150Mouse
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1301980Fcsa5_mfemoral cross-sectional area 5 (mouse)Not determined2767911541679261Mouse
1301790Pcfm1_mperiosteal circumference and femur length 1 (mouse)Not determined2823629642236396Mouse
10043876Adip22_madiposity 22 (mouse)Not determined2830805142308240Mouse
1300624Insq7_minsulin QTL 7 (mouse)Not determined2938444643384575Mouse
10755513Amzn4_manatomical modifier of Zfp423 4 (mouse)2938444643384575Mouse
12903993Opfaq1_mopen field activity QTL 1 (mouse)2967669127022642Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NR_037262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AL772216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000103868
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl210,496,497 - 10,496,583 (+)Ensembl
RefSeq Acc Id: ENSMUST00000103884
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl210,501,308 - 10,501,394 (+)Ensembl
RefSeq Acc Id: NR_037262
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39210,501,308 - 10,501,394 (+)NCBI
GRCm38210,496,497 - 10,496,583 (+)ENTREZGENE
Celera210,422,268 - 10,422,352 (+)ENTREZGENE
cM Map2 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000093900 Ensembl
  ENSMUSG00000119195 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000103884 ENTREZGENE
MGD MGI:4834292 ENTREZGENE
miRBase MI0014071 ENTREZGENE
NCBI Gene 100526538 ENTREZGENE
PhenoGen Mir669p-2 PhenoGen
RNAcentral URS00002AA0E2 RNACentral
  URS00005FA00A RNACentral
  URS000075A33D RNACentral